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IDEXX 

Catalyst One

Chemistry Analyzer

Operator’s Guide

Summary of Contents for Catalyst One

Page 1: ...IDEXX Catalyst One Chemistry Analyzer Operator s Guide...

Page 2: ...yrights or other intellectual or industrial property rights covering this document or subject matter in this document The furnishing of this document does not give a license to these property rights e...

Page 3: ...ing 14 Diluting Samples 14 Viewing and Printing Test Results 16 Outside of Reportable Range Samples 17 Modifying the Settings on the Analyzer 18 Modifying the Sound Settings 18 Entering Standby Mode 1...

Page 4: ...nalyzer 28 Cleaning the Outside of the Analyzer and the Sample Drawer 29 Emptying the Waste Drawer 29 Appendices 30 Chemistry Descriptions 30 Medical Protocol Descriptions 51 Profile Selection 56 Diff...

Page 5: ...ter or other liquids Performance Precaution Do not use certain liquids aerosols such as canned air solvents ammonia and other substances on or near the analyzer which could influence results Care of t...

Page 6: ...er la notice d utilisation Gebrauchsanweisung beachten Consultare le istruzioni per l uso Consultar las instrucciones de uso Catalog number Num ro catalogue Bestellnummer Numero di catalogo N mero de...

Page 7: ...el auf elektrostatische Ladung Dispositivo sensibile alle scariche elettrostatiche Keep dry Conserver dans un endroit sec Mantener seco Vor N sse sch tzen Tenere al riparo dall umidit Fragile Fragile...

Page 8: ...sease progression with parameter trending capabilities and more By connecting the Catalyst One analyzer to the IDEXX VetLab Station you can Automatically review patients prior results on every printou...

Page 9: ...er measures the color development of the slide and then all used materials are removed from the analyzer Catalyst One Components Front of the Analyzer Side door Sample drawer Waste drawer Inside of th...

Page 10: ...ts icon on the IDEXX VetLab Station Home screen LED Color Description Green steady READY analyzer is ready to process samples or perform maintenance tasks Green pulse STANDBY MODE Yellow steady IN PRO...

Page 11: ...bvious sources of heat direct sunlight cold humidity or vibrations For optimum results room temperature should be at 15 C 30 C 59 F 86 F and relative humidity at 15 75 IMPORTANT Ensure proper ventilat...

Page 12: ...Alanine Aminotransferase ALT Amylase AMYL Aspartate Aminotransferase AST Blood Urea Nitrogen BUN Calcium Ca Cholesterol CHOL Creatine Kinase CK Creatinine CREA Chloride Cl Fructosamine FRU Gamma glut...

Page 13: ...ep Avian budgerigar cockatoos grey cheek Moluccan umbrella cockatiel canary conure macaw blue and gold hyacinth scarlet parrots Amazon blue Amazon yellow eclectus African grey Monkey Snake Mouse Torto...

Page 14: ...loaded within 5 minutes of opening their foil packaging The Lyte 4 CLIP should be loaded within 2 minutes of opening its foil packaging If you are running a Lyte 4 CLIP be sure to load it in the sampl...

Page 15: ...concentration the sample should be diluted manually An automated dilution run will be canceled if There is insufficient diluent sample volume There are too many slides in the run Minimum Sample Volum...

Page 16: ...6 1 100 L 6 600 L 7 1 100 L 7 700 L 8 1 100 L 8 800 L 9 1 100 L 9 900 L 10 1 100 L 10 1 000 L 11 Viewing and Printing Test Results Analyzer results are automatically returned to the IDEXX VetLab Stati...

Page 17: ...mmol L 50 160 mmol L 50 160 mmol L CREA 0 1 13 6 mg dL 9 1202 mol L 1 0 136 0 mg L FRU 100 1 000 mol L 100 1 000 mol L 100 1 000 mol L GGT 0 952 U L 0 952 U L 0 952 U L GLU 10 686 mg dL 0 56 38 11 mmo...

Page 18: ...etLab Station Home screen 2 Tap the Catalyst One side tab 3 If you do not want the analyzer to ever enter Standby mode tap Never in the Standby area OR 4 If you want the analyzer to enter Standby mode...

Page 19: ...15 CLIP N A NSAID 6 CLIP N A UPC Panel N A Lyte 4 CLIP N A Albumin ALB Alkaline Phosphatase ALKP Alanine Aminotransferase ALT Amylase AMYL Aspartate Aminotransferase AST Blood Urea Nitrogen BUN UREA C...

Page 20: ...parator except when running feline AST LDH or CK Double dosing may elevate the results for these assays in feline samples 3 Gently swirl do not invert or shake the whole blood separator at least 5 tim...

Page 21: ...eing used in the run for more information see Proper Sample Cup Volume on page 22 To Prepare a Urine Sample 1 Obtain the sample through cystocentesis recommended catheter or free catch method 2 Transf...

Page 22: ...rim the serum plasma with a wooden stick respin the sample and proceed Various conditions such as hemolysis may affect results You might also want to modify your test panel based on the following visu...

Page 23: ...Notes For additional information on the effects of delays in removing serum or plasma from the cells see the Chemistry Descriptions section on pages 30 51 See the calcium Ca total bilirubin TBIL lact...

Page 24: ...rol vials within 24 hours Expired or unwanted material should be discarded with other clinical waste Note Do not store in the freezer door only in the main freezer compartment Stability and Handling F...

Page 25: ...uality Control CLIPs and Slides IDEXX recommends that you perform monthly quality control testing after you have cleaned the internal components of your analyzer The convenient Catalyst QC CLIP contai...

Page 26: ...uent to the control vial using a clean dry Class A volumetric pipette or an equivalent automatic pipette Discard the remaining diluent IMPORTANT Measurement must be precise or results will be incorrec...

Page 27: ...e cup Note You will need one PHBR slide wash and one PHBR slide for the quality control procedure 4 Run quality control on the analyzer Running Quality Control To Run General Quality Control on the Ca...

Page 28: ...eaning the Internal Components of the Analyzer To ensure optimal performance of your analyzer it is important that you clean the internal components incubator ring optics window and carousel monthly a...

Page 29: ...ing near the analyzer organic solvents ammonia based cleaning products ink markers sprays containing volatile liquids insecticides disinfectant polish or room freshener Care should be taken not to spi...

Page 30: ...therapy However many individual chemistry tests give information about different organ systems and should be used in combination with other tests panels or profiles to help characterize disease Alanin...

Page 31: ...Sample Type and Precautions Remove plasma or serum promptly from the cells or clot Hemolysis may occur if the sample is not handled properly Although dry slide technology minimizes the interfering eff...

Page 32: ...be used because ALKP contamination from red blood cells will increase results while hemoglobin decreases results Above normal total bilirubin levels may reduce ALKP results Complementary Tests Alkalin...

Page 33: ...zed samples Blood samples should be taken within one day of the onset of symptoms that suggest acute pancreatitis Complementary Tests Amylase and lipase are usually determined in conjunction with one...

Page 34: ...ther tests of liver cardiac or skeletal muscle function or damage Reaction Sequence Blood Urea Nitrogen BUN The catabolism of proteins results in the production of ammonia which is extremely toxic Amm...

Page 35: ...ith resultant hyperphosphatemia dietary spurious Sample Type and Precautions Remove plasma or serum promptly from the cells or clot If plasma is being collected use only lithium heparinized samples Ce...

Page 36: ...ium potassium chloride and bicarbonate are measured together accurate assessment of metabolic acid base physiology is possible Reaction Sequence Cholesterol CHOL Serum cholesterol occurs predominantly...

Page 37: ...and centrifuged immediately after drawing blood Blood samples should be taken within 6 hours of a suspect lesion It is important to determine that the patient has not been exercised vigorously during...

Page 38: ...s essential for proper interpretation of increases in creatinine Creatinine determinations should usually be performed in conjunction with measurements of BUN inorganic phosphate total protein and alb...

Page 39: ...rked hemolysis will lower the reported value on the Catalyst analyzers Reaction Sequence Gamma glutamyltransferase GGT The enzyme gamma glutamyltransferase is membrane bound It is present in large qua...

Page 40: ...te Samples must be centrifuged completely Remove serum promptly from the clot to avoid metabolism of glucose by the cells A maximum of 30 minutes between drawing and separation from the clot is recomm...

Page 41: ...found in the cell cytoplasm and is released into the blood during reversible and irreversible necrosis cell injury The test is not a specific or sensitive indicator of damage to any organ or tissue No...

Page 42: ...red cells within 5 minutes of collection Complementary Tests CBC biochemical panel complete urinalysis and blood gas Reaction Sequence Lipase LIPA Lipase is secreted by the pancreas and to a lesser e...

Page 43: ...nce of measuring serum magnesium concentration in dogs and cats has not been fully investigated However there have been reports of hypomagnesemia in dogs following the removal of the parathyroid gland...

Page 44: ...y state is achieved timing of sample collection is not important in more than 90 of patients However there can be variability of the phenobarbital half life in a small percentage of patients Therefore...

Page 45: ...icism Reaction Sequence Sodium Na Sodium is the major cation of extracellular fluid where it maintains osmotic pressure acid base balance and transmits nerve impulses The body maintains total sodium c...

Page 46: ...d cats the concentration of total bilirubin in the serum is very low Visual inspection of the sample will frequently indicate whether bilirubin determination is necessary serum and plasma only Most Co...

Page 47: ...If plasma is collected use only lithium heparinized samples Moderate to marked hemolysis can result in false high total protein concentration Results obtained from the analysis of plasma may be slight...

Page 48: ...in confirming hypothyroidism Cats with consistent clinical signs and total T4 TT4 values in the borderline high range gray zone may have early hyperthyroidism or a concurrent nonthyroidal illness NTI...

Page 49: ...id prerenal postrenal and renal azotemia associated with decreased glomerular filtration rate Sample Type and Precautions Remove plasma or serum promptly from the cells or clot If plasma is collected...

Page 50: ...rs to avoid evaporation and contamination Samples may be stored at room temperature for up to 3 days refrigeration preferred Frozen samples can be stored indefinitely Reaction Sequence Urine Protein U...

Page 51: ...ach tube or gelatin capsules A second sample is drawn 30 minutes after ammonium chloride administration Note Vomiting during the procedure will invalidate results Sample Requirements 1 mL heparinized...

Page 52: ...igation and management for the underlying cause Renal proteinuria evaluate in the face of azotemia Nonazotemic persistent renal proteinuria dogs and cats UPC 0 5 within reference range UPC 0 5 1 0 que...

Page 53: ...53 Appendices...

Page 54: ...ysis Low T4 1 0 g dL 13 0 nmol L Low T4 with NTI 1 0 g dL 13 0 nmol L Normal T4 2 0 4 0 g dL 26 0 51 0 nmol L Hypothyroidism unlikely fT4 TSH TgAA Low fT4 high TSH positive TgAA Hypothyroidism likely...

Page 55: ...ous Feline hyperthyroidism suspected Normal T4 0 8 4 7 g dL 10 0 30 0 nmol L Low T4 0 8 g dL 10 0 nmol L High T4 4 7 g dL 60 0 nmol L Hyperthyroidism likely Hyperthyroidism unlikely Euthyroid sick or...

Page 56: ...amples Acute pancreatitis is suspected Renal disease is suspected Chem 17 CLIP Chem 15 CLIP Chem 10 CLIP Gastrointestinal profile Cardiac profile Endocrine profile Hepatic profile Lipid profile Pancre...

Page 57: ...commercial laboratory as appropriate Each result should have the same relationship to its method s reference range For instance a sample giving a Catalyst One result that is slightly below the Catalys...

Page 58: ...Free Technical Support 00800 1234 3399 Telephone 34 932 672 660 Fax 00800 1234 3333 idexx es United Kingdom IDEXX Laboratories Ltd Riverside House Riverside Walk Windsor Berkshire SL4 1NA United King...

Page 59: ...ntie 16 A 3 00100 Helsinki Finland Telephone 0800 98458 idexx fi Norway IDEXX Laboratories Norge AS c o Corpnordic Norway AS v Sunde Bryggetorvet 1 0250 Oslo Norway Telephone 80031026 idexx no Sweden...

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