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esca User’s Manual v1.2 

 

 

 

I

NTRODUCTION

 

 

I

NTRODUCTION TO 

ESCA 

 

ESCA  (Elements  Single  Channel  Amplifier)  is  a  current  measurement  system  entirely 
contained in a USB stick designed for voltage clamp experiments. 

Thanks  to  a  custom-made  microchip  for  low-noise  current  signal  acquisitions,  ESCA 
achieves  high performances in a very small size package. 

The main features of ESCA are: 

-

 

two input current ranges: ±200 pA and ±20 nA; 

-

 

4 selectable signal filters: 625 Hz, 1.25 kHz, 5 kHz and 10 kHz; 

-

 

very low noise: 

 80 fA rms at 625 Hz & < 400 fA rms at 10 kHz (open input); 

-

 

integrated voltage stimulus in the range of ±355 mV with 1mV resolution; 

-

 

SMB input coaxial connector. Several adapters available; 

-

 

small size (30x15x74mm); 

-

 

software included; 

 

H

ARDWARE 

S

ETUP

 

 

ESCA  is  designed  to  be  as  simple  as  possible  to  connect  to  your  various  different 
setups. 

In  order  to  obtain  the  best  performance,  the  main  things  to  be  careful  are  parasitic 
capacitances on the input and correct shielding of the overall hardware setup to avoid 
the 50/60Hz line interferences and other electromagnetic interferences. 

An adequate faraday cage must be used. The faraday cage should be large enough to 
contain all your sensitive equipment and must be connected to the common ground. 

Be careful to avoid ground loops by using a “star ground” connection. 

Be careful to keep the input sensitive line as far as possible from the faraday cage walls 
to limit the parasitic capacitances on the input as much as possible. 

The following paragraphs describe all the connections and how to connect them in the 
right way. 

 

Summary of Contents for esca

Page 1: ...esca Elements Single Channel Amplifier User s Manual v1 2 February 2014...

Page 2: ...esca User s Manual v1 2 CONTACTS Elements s r l via Montalti 42 47521 Cesena ITALY email info elements ic com web www elements ic com...

Page 3: ...SETUP 4 Front Connections 5 Rear Connections 5 Tipical Experimental Setup 5 SOFTWARE GUIDE 6 Requirements 7 Installation 7 Software Operating Procedure 9 Graphical User Interface 10 ESCA Setup 11 Digi...

Page 4: ...all size 30x15x74mm software included HARDWARE SETUP ESCA is designed to be as simple as possible to connect to your various different setups In order to obtain the best performance the main things to...

Page 5: ...ct is the reference voltage IMPORTANT Do NOT short the reference to the ground REAR CONNECTIONS On the rear of ESCA there are two connectors mini B female USB connector to connect to the PC through th...

Page 6: ...ssible from the Faraday cage including your Device Under Test DUT With certain PC there can be some issues with USB power supply that can introduce noise and peaks on the acquired signal In these case...

Page 7: ...ements are Dual core processor 1GHz or better 1GB of RAM A free USB 2 0 port Windows XP Vista Seven 8 INSTALLATION To start the installation procedure double click on the installation executable EDR_s...

Page 8: ...esca User s Manual v1 2 Click on Extract to prepare the installation of these drivers Then start the FTDI installation by clicking on Next button and wait until installation finishes...

Page 9: ...ree USB port The first time you connect the ESCA to your PC you must wait for the new USB device complete recognition NOTE If the blue LED in the rear of ESCA doesn t light up or if you receive an ins...

Page 10: ...with the ESCA hardware The configuration file is loaded by clicking on the Open Config button The configuration file is ESCA_xxx cfg where xxx is the firmware version of your ESCA device The configura...

Page 11: ...addition to the Open Config button already described in the previous section the following buttons Connect Starts the communication with the ESCA hardware Show Displays the data visualization window...

Page 12: ...the next section the digital compensation is described The Triangular Wave check box is used to force a 48 Hz triangular wave control voltage of peak to peak amplitude of 118 mVpp This voltage signal...

Page 13: ...software includes some statistical data analysis done in real time during the current acquisitions These estimated statistic data are Mean value Standard Deviation STD Equivalent input capacitance Equ...

Page 14: ...on the R estimation button The Saturation indicator means the input current exceeded the maximum or minimum current value for the selected Range TRACE VISUALIZATION The data visualization is based on...

Page 15: ...om level Set vertical 0 point in the middle of the window Change the grid dimensions Change the vertical offset shift Change the horizontal offset shift Search for a channel NB useless with ESCA devic...

Page 16: ...mat used by commercial pClamp software from Molecular Devices First choose which format will be used by clicking on File Preferences To start saving data click on the Save button The data are saved in...

Page 17: ...es are stored in standard 32 bit single precision format little endian The ESCAread Matlab function will ask you the location of the saved data files and the data bandwidth The function returns in thr...

Page 18: ...an array with 2 columns 1 channels vc C reshape B 1 2 fix length B 2 2 D C select sampling frequency display Select bandwidth display 1 625 Hz display 2 1 25 kHz display 3 5 kHz display 4 10 kHz sel i...

Page 19: ...esca User s Manual v1 2...

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