CAMAG TLC-MS INTERFACE 2, Instruction Manual

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Content
1 Introduction ................................................................................................................................................... 2
1.1 Precaution ............................................................................................................................................... 2
1.2 Parts supplied .......................................................................................................................................... 3
2 Unpacking/Installation .................................................................................................................................. 4
2.1 Unpacking ............................................................................................................................................... 4
2.2 Installation environment .......................................................................................................................... 4
2.3 Installation .............................................................................................................................................. 4
2.4 Connection of the valve ........................................................................................................................... 5
3 Getting started .............................................................................................................................................. 6
3.1 Intended use ........................................................................................................................................... 6
3.2 Instrument .............................................................................................................................................. 6
3.3 Functional principle ................................................................................................................................. 7
3.4 Elution process ........................................................................................................................................ 9
3.5 Operation advice ................................................................................................................................... 10
4 Maintenance and Service ............................................................................................................................ 10
4.1 Cleaning ................................................................................................................................................ 10
4.2 Decontamination ................................................................................................................................... 10
4.3 User maintenance.................................................................................................................................. 11
4.4 Maintenance Data Sheet ....................................................................................................................... 11
4.5 Replacing of elution head ...................................................................................................................... 12
5 Technical data .............................................................................................................................................. 12
6 Application hints ......................................................................................................................................... 13
6.1 Practical procedure for elution ............................................................................................................... 13
6.2 Fittings .................................................................................................................................................. 15
6.3 Dead volumes ....................................................................................................................................... 17
6.4 System leaks .......................................................................................................................................... 18
Telltale signs of system leaks .......................................................................................................................... 18
6.5 Application example .............................................................................................................................. 19
Sample: diclofenac in methanol at a concentration of 0.113 mg/mL ............................................................... 19
Separation of Caffeine, Paracetamol, Acetylsalicylic Acid................................................................................. 20
Results ........................................................................................................................................................... 22
EC Declaration of Conformity