Column heater
Sample manager
Binary solvent manager
The ACQUITY UPLC I-Class Series core system includes a binary solvent manager, a sample
manager - flow through needle or sample manager - fixed loop (SM-FTN or SM-FL), a column
heater (CH-A), detectors (tunable ultraviolet, photodiode array, eλ photodiode array, or mass
spectrometry), and an ACQUITY UPLC column.
Waters Empower chromatography data software, MassLynx mass spectrometry software, stand-
alone ACQUITY UPLC Console software, or Analyst software controls the system.
1.7.1 Binary solvent manager (BSM)
The Waters ACQUITY UPLC I-Class Series binary solvent manager (BSM) delivers solvent
compositions for isocratic and binary gradient methods at flow rates of 0.01 to 2.0 mL per minute.
Its features include in-line filters upstream of a primary check valve, the Waters Intelligent Intake
Valve (i2Valve), automated priming functions, and daily system-setup routines.
The design of the binary solvent manager is optimized for sub-2-μm particle liquid
chromatography. The upper pressure limit is set at 124,106 kPa (1241 bar, 18,000 psi) per pump.
A maximum flow rate of 1 mL/min is permitted at system backpressures to 124,106 kPa (1241
bar, 18,000 psi), which falls within the range of optimal linear velocity for sub-2-μm particle
columns of ID 1.0 mm to 3.0 mm.
See also:
ACQUITY UPLC Binary Solvent Manager PLUS Overview and Maintenance Guide
on
your documentation media, or at
, for more details.
Note:
An optional degasser vent line extension exists for applications requiring longer tubing
lengths. For more information, contact your local Waters distributor.
1.7.2 Sample manager-FTN (SM-FTN)
The ACQUITY UPLC I-Class Series sample manager - flow through needle (SM-FTN) differs
from a loop-based injector. The mechanism aspirates a sample from plates and vials and holds it
in the sample needle in preparation for injecting the sample onto the column. The needle serves
as part of the injection flow path when the sample is pushed onto the column.
Optional extension loops (installed between the sample needle and the injection valve) can
increase the injection volume beyond that of the sample needle. The SM-FTN can also dilute
samples using the auto-dilution option.
Using the flow through needle (FTN) mechanism, the system operates similarly to most traditional
HPLC systems, which facilitate the transfer of HPLC methods. The FTN mechanism also does
not require you to learn new injection modes. Also, it achieves injection accuracy and decreases
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