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Operators Handbook DCU3 – System

14., Supplement

BAEDCU3 - Rev. 4.6 - 0504

14 - 6

14.4 Abbreviations

All entries in the operation display depend on the individual configuration of the DCU-
system. The standard configurations use the following terms :

14.4.1 Process

Values

Abbreviation Meaning

TEMP

Temperature culture vessel

JTEMP Temperature

double

wall

STIRR stirrer

speed

MOTCR motor

currency

pH pH-value

pO2

partial pressure of oxygen

ACID

dosing counter acid pump (delivered volume)

BASE

dosing counter alkali pump (delivered volume)

AFOAM

dosing counter antifoam agent pump (delivered volume)

SUBS

process value nutrient solution pump

AIRFL

process value delivery air inlet

REDOX

measured Redox, signal from probe

PRESS

measured pressure, signal from sensor

WEIGH

weight measured by balance system (PHILIPS-type)

HARV

dosing counter harvest pump

FEEDP

dosing counter substrate pump

GAS1

process value delivery volume gas 1

GAS2

process value delivery volume gas 2

FLOW actual

massflow

FWEIG

weight measured by balanced connected via 1. serial interface (SARTO-
RIUS-type balance)

Содержание DCU 3

Страница 1: ...Operators Handbook BAEDCU3 Rev 4 6 0504 D C U 3 S y s t e m Digital Measurement and Control System for Fermentors...

Страница 2: ......

Страница 3: ...or can be combined into a project specific document Design installation start up and use of the fermentor system are shown in the extra operating manual of this unit More detailed technical informati...

Страница 4: ...Operators Handbook DCU3 System Introduction BAEDCU3 Rev 4 6 0504...

Страница 5: ...ed by the Main Menu 4 1 5 Main Function Calibration 5 1 General Note 5 1 5 2 pH Calibration 5 2 5 3 pO2 Calibration 5 4 5 4 Redox Calibration 5 5 5 5 Calibration of Turbidimetry Measurement 5 6 5 6 To...

Страница 6: ...29 6 19 Pressure Controller 6 30 6 20 Gravimetric Dosing Controller 6 31 6 21 Setpoint Profiles 6 33 6 22 Timers 6 35 6 23 Alarm Limits of Process Values 6 37 6 24 Alarms of Digital Inputs 6 39 7 Main...

Страница 7: ...tion Menu 10 1 10 2 Report Printer 10 1 10 3 Recorder Configuration 10 3 11 Main Function Password 11 1 12 Main Function INFO 12 1 13 Alarms 13 1 Alarm Messages 13 1 13 2 Alarm Menu 13 2 14 Supplement...

Страница 8: ...Operators Handbook DCU3 System Contents BAEDCU3 Rev 4 6 0504...

Страница 9: ...stem will always depend on the specifications of the customer as agreed prior to ordering of the fermentor system Therefore even specific customized configurations are possible Standard functions are...

Страница 10: ...Operators Handbook DCU3 System 1 Design and Function BAEDCU3 Rev 4 6 0504 1 2...

Страница 11: ...ing switched on again the DCU3 will start at return to a defined state of operation All controllers are off actuators are in rest position All timers are off stopped No recipe loaded no program steril...

Страница 12: ...tes the shut down function Then all outputs of the DCU are reactivated 2 4 Interlocking Functions Interlocking functions trigger the outputs for functions which are important for operational safety i...

Страница 13: ...able to provide an optimum angle of vision DCU Tower BIOSTAT B DCU 1 Unscrew the locating screw of the support at the rear of the terminal a little 2 Push the terminal backward at its upper edge or pu...

Страница 14: ...mate dd mm yyyy hh mm ss 2 line Alarm line display of alarms showing the latest alarm 3 line name of active function in the working area Working area display of schematic setup of fermentor system and...

Страница 15: ...ailable in the working area of the oper ating displays Selection key Function Exit Closes the actual display PARAM Request for display of related parameters PV Alarm Request for display of related pro...

Страница 16: ...larm parameters Maintenance Manual access to inputs and outputs measurement ranges of process values parameters of remote systems such as host computers balance systems and to the maintenance service...

Страница 17: ...ls At multible vessel fermentor systems the main menus of the subunits can be accessed as follows Via the touch key integrated in the overview display showing the vessel no of the subunit only for DCU...

Страница 18: ...tors Handbook DCU3 System 3 Function Selection and Inputs BAEDCU3 Rev 4 6 0504 3 6 Switching over the main menu dis plays for 2 4 culture vessels via direct function key CHANGE UNIT CHANGE UNIT CHANGE...

Страница 19: ...rating terminal Applicable for DCU3 system which are prepared for controlling several fermentors culture vessels 3 2 Inputs 3 2 1 Numerical and Non numerical Inputs Example for entering numerical inpu...

Страница 20: ...accessed Special Notes What do touch keys indicate whose label appears in black white dithered light letters If a controller s mode is set to auto for instance the data entry for the controller output...

Страница 21: ...s parameters Above this it is the starting point for easy access to the submenus and subfunctions for inputs and selections 4 2 Process Information Provided by the Main Menu The main menu displays the...

Страница 22: ...n this laser printed manual shown light grey see example for the entry of foam measurement 4 2 2 Invalid Process Values If a process value is invalid the display changes to see example flow 4 2 3 Dire...

Страница 23: ...ion agent pumps for dosing counters Balance the functions required for pre setting of balance systems such as zero taring and tare correction You will enter all inputs at the touch terminal Context ba...

Страница 24: ...mpact of heat during the sterilization can cause a zero drift of the electrode To compensate for such effects the DCU3 system allows to recalibrate the pH electrode during the process You can measure...

Страница 25: ...h the culture medium for instance 1 Measure the actual pH value in a sample taken from the running fermentation using con ventional pH measuring techniques 2 Start the calibration by pressing the Star...

Страница 26: ...O2 the actually measured electrode current the actual temperature and the zero and slope current together with the calibration conditions This in addition allows a simple function control of the pO2 e...

Страница 27: ...eys values and functions available in this display REFBU mV Enter reference voltage of redox buffer 5 4 2 Functional Check The electrode function is checked before it is mounted into the culture vesse...

Страница 28: ...and the zero deviation against 0 AU This allows for an easy func tional check of the sensor The lamp contained in the turbidimetry sensor can be switched on and off via the Sensor Calibration menu se...

Страница 29: ...sensor proceed as follows 1 Start the calibration via Start Calibration 2 Follow the instructions of the calibration menu 5 5 3 Special Notes 1 If the lamp1 is switched on it will be kept in on state...

Страница 30: ...calibration process from the measured running time and the entered delivery volume The standard configurations of the DCU system include calibration routines and dosing counters for acid base antifoam...

Страница 31: ...he pump 2 Start the calibration of the pump via Start Calibration 3 Follow the instructions shown at in the DCU3 display The DCU system automatically calculates the flowrate considering the internally...

Страница 32: ...rrection is possible after changing the equipment of the culture vessel during a running process For this the net weight is stored and the tare weight will be adapted to the changing gross weight 5 7...

Страница 33: ...to the DCU3 without hardware extensions One extension allows for up to 12 measurements The system calculates the volume delivered per time the massflow considering the actual weight measured with the...

Страница 34: ...is calculated from the shortest interval This is also true when a new setpoint is defined for the dosing controller The same is true for presetting a new setpoint of the dosing controller 3 For manua...

Страница 35: ...mputer The extent of implemented controllers depend on the fermentor system and or the individual customized configuration The controllers shown below can be implemented at present Temperature control...

Страница 36: ...ending on process value SETP PV input of setpoint entry physical unit depending on process value MODE input of controller mode off master controller and servo controller switched off auto master contr...

Страница 37: ...egC for TEMP rpm for STIRR pH for pH value sat for O2 saturation etc SETP PV Input of setpoint in the physical unit of the process value such as degC for TEMP rpm for STIRR pH for pH value etc MODE In...

Страница 38: ...and PID controllers the controller outputs can be limited MIN and MAX Thus unintended high actuator changes can be avoided and for cascade controllers the setpoint for the servo controller can be limi...

Страница 39: ...e of process value MAX Input of minimum output limit representing the setpoint minimum for the servo controller 0 100 measuring range of process value DEADB PV Input of deadband physical unit dependin...

Страница 40: ...roller alle PID Parameter defined 6 4 5 PID Controller Optimization An optimum adaptation of a PID controller to its control loop requires detailed knowledge in control theory You may refer to any sta...

Страница 41: ...he set point which minimizes overshooting When the temperature controller is switched off an additional digital output switches off the circulation pump and the heating contactor in the fermentor The...

Страница 42: ...JTEMP 6 5 4 Special Notes When the master controller is in auto or profile mode the servo controller is automatically switched over into cascade mode When the master controller is in off mode the ser...

Страница 43: ...peed controller can be switched as a servo controller in the pO2 cascade control loop 6 6 1 Operating Display For a description of the tags the physical units or entries the displayed value or functio...

Страница 44: ...neral 6 7 2 Special Notes In manual mode when entering the MIN MAX output limits and entering data into OUT allways observe the permissible measuring range of the corresponding airflow rate BIOSTAT ED...

Страница 45: ...ption of the tags the physical units or entries the displayed value or function and of the required inputs see the table in section 6 3 Controller Operation in General 6 8 2 Operating Information For...

Страница 46: ...ic MIN MAX range for the setpoint signal transmitted to each servo controller When the pO2 control is switched on at first the output of the pO2 controller operates the setpoint input of the priority...

Страница 47: ...in section 6 3 Controller Operation in General Additional functions of this Operating Display are the following Tag Entry Displayed value or function required input CASCADE Input of servo controller f...

Страница 48: ...maximum setpoint for servo controller 0 100 measuring range process value XP Input of proportional range for servo controller PARAM in rela tion to measuring range TI sec Input of reset time ifor ser...

Страница 49: ...erned is out of its range for the delay time set in HTIME After this delay period the switch over condition will be checked again and the controllers then be switched over only if the condition is sti...

Страница 50: ...iption of the tags the physical units or entries the displayed value or function and of the required inputs see the table in section 6 3 Controller Operation in General Additional functions of this Op...

Страница 51: ...Input of minimum output limit considering the minimum setpoint for servo controller 0 100 measuring range process value Maximum Input of maximum output limit i e the maximum setpoint for servo contro...

Страница 52: ...ble in section 6 3 Controller Operation in General 6 12 2 Special Notes Depending on the process requirements the control can be based on the following gases alternate supply of N2 and air at low O2 c...

Страница 53: ...ntroller and can be used in two modes Control of the total gas flow TOTAL The setpoint for the total flow is manually adjusted The pO2 gasflow controller provides a setpoint for the portion of Gas 1 R...

Страница 54: ...GAS2 slpm Flowrate Gas2 e g air RATIO Input of ratio of Gas 1 to total flowrate external setpoint in mode cascade master controller Contr has access to RATIO TOTAL slpm Input of total flowrate of Gas1...

Страница 55: ...e defined only once Afterwards only setpoint and controller mode of the master controller pO2GF need be set 6 13 5 Special Notes In the operating modes auto and profile of the master controller the se...

Страница 56: ...tem reduces the flow rate of the massflow controller for air supply and triggers a second massflow controller to add oxygen to the air inlet The increase of oxygen input is propertional to the decreas...

Страница 57: ...e or function and of the required inputs see the table in section 6 3 Controller Operation in General Additional functions of this Operating Display are the following Tag Entry Displayed value or func...

Страница 58: ...agent to the culture The pump or dosing valve is switched on and off periodically The dosing times and cycle time for intermittent operation can be entered into the control display 6 15 1 Operating D...

Страница 59: ...foam sensor should be set as low as possible 1 Reduce the sensitivity down from position high until only foam is just detected 2 Adjust the cycle time CYCLE and the dosing time according to your proc...

Страница 60: ...equipped with an output for measured signal Above this the extended functions of the DCU3 system allow the specification of time profiles for set points as well as recipe dependent setpoints for the...

Страница 61: ...the DCU3 system offers several control strategies that can be selected the operator according to the requirements of the process 6 17 1 1 Single Sensor Control with Harvest Pump Control This control m...

Страница 62: ...e on active inputs only in mode manual PULSE m s Input of reset time for the pump in minutes seconds SENSI low high Setting of the sensitivity for the amplifier DI ALARM Enabling the display of digita...

Страница 63: ...via pulse width modulated outputs 6 18 1 Operating Display For a description of the tags the physical units or entries the displayed value or function and of the required inputs see the table in sect...

Страница 64: ...a an I P converter The pressure controller can operate as a servo controller in the pO2 cascade control circuit 6 19 1 Operating Display For a description of the tags the physical units or entries the...

Страница 65: ...ered volume considering the weight change It can ensure a constant flow by continuous control of the external pump This control function directly acts upon the input weight signal delivered from the b...

Страница 66: ...ing range of the controller output OUT must be within 15 90 For this the delivery of the pump can be preselected by use of a tubing of the appropriate size or a pump head with an appropriate membrane...

Страница 67: ...Temperature Control Profile Tag Entry Displayed value or function required input MODE Input of status of the profile stop profile inactive after loading of recipe start setpoint profile automatically...

Страница 68: ...etpoint profile is started the controller mode in the main menu CONTROL LOOPS is automatically switched over to profile If the time for the first breakpoint is not set to 00 00 h m the system uses the...

Страница 69: ...be processed The timers can be started and stopped at any time For running timers the display shows the passed time ELAPT 6 22 1 Operator Display Tag Entry Displayed value or function required input...

Страница 70: ...le for timer operation in profile mode 6 22 3 Special Notes If the timer runs in the MODE profile the program must start at the time 00 00 h m In the profile mode the last condition programmed for the...

Страница 71: ...m can be confirmed via the ACK key and the next alarm is displayed An alarm buffer stores up to 20 alarm messages not being confirmed The latest alarm is displayed on the alarm line on the screen Curr...

Страница 72: ...e ACK nowledge key to confirm This also deletes this alarm message 2 The display of the process value changes its colour to red The DCU System displays an alarm as long as the process value exceeds th...

Страница 73: ...d in customized DCU configurations 6 24 1 Operating Display Tag Entry Displayed value or function required input ALARM MODE Input for selection of the alarm monitoring disab Alarm monitoring of digita...

Страница 74: ...Operators Handbook DCU3 System 6 Main function Control Loops BAEDCU3 Rev 4 6 0504 6 40...

Страница 75: ...i zation medium sterilization sterilization of transfer installations intermediate sterilization for air inlet filter and for exhaust filter etc The structure of sterilization programs such as step ch...

Страница 76: ...the sterilization such as opening or closing manual valves a corresponding message appears on the display The automatic sterilization will only continue after the required step is done and you have co...

Страница 77: ...ossible since another sequence or recipe is active inactive sterilization program inactive ACK Request for Acknowledgement display see alarm messages in the supplement PHASE Display of the sterilizati...

Страница 78: ...program the top line displays the process status STATE active If the process time has not yet been activated it will automatically start when the sterilization program is started Running sterilization...

Страница 79: ...ss time clock at zero or at a predefined time If no process time is active the clock starts automatically with the sterilization program or when a recipe is loaded for the first time 7 3 1 Operating D...

Страница 80: ...Operators Handbook DCU3 System 7 Main function Batch Control BAEDCU3 Rev 4 6 0504 7 6...

Страница 81: ...cesses You can create up to four different recipes from the following sets of parameters Setpoints and operating modes of controllers Setpoint profiles for controllers Timer parameters Alarm limits an...

Страница 82: ...Operators Handbook DCU3 System 8 Main Function Recipes BAEDCU3 Rev 4 6 0504 8 2 After selecting a recipe you can select the recipe parameter sets via the following menu...

Страница 83: ...pe you can switch over the mode for this controller to no change during input of the recipe parameters 8 3 1 Operating Display Example for Temperature Controller Tag Entry Displayed value or function...

Страница 84: ...Temperature Controller Tag Entry Displayed value or function required input MODE Additional input of state of profile for recipe Setpoint profile will not be effected by the recipe 8 4 2 Special Notes...

Страница 85: ...ut MODE Additional state of timer for recipe no change recipe does not effect the timer 8 5 2 Special Notes Detailed information about the timers is included in section 6 22 Timers Timers that should...

Страница 86: ...e recipes should not influence the alarm monitoring for certain process variables the alarm state must be set to no change while entering the corresponding recipe 8 6 1 Operating Display Tag Entry Dis...

Страница 87: ...f a digital input should not be influenced by a recipe the alarm state of this digital input must be set to no change when entering the recipe 8 7 1 Operating Display Tag Entry Displayed value or func...

Страница 88: ...Operators Handbook DCU3 System 8 Main Function Recipes BAEDCU3 Rev 4 6 0504 8 8...

Страница 89: ...a a selection menu 9 1 1 Selection Menu Maintenance Note Most of the functions for system maintenance and trouble shooting are password pro tected to prevent unauthorized access Access to maintenance...

Страница 90: ...into their corresponding menu to simulate a process Settings entered in manual mode have top priority they will override all other settings and functions of inputs and outputs of the DCU system 9 3 Ma...

Страница 91: ...cal channel assignment DIMnn Digital Input Measurements internal digital inputs of measurement amplifiers DIPnn Digital Input Process digital input from process 9 3 3 Special Notes The following signa...

Страница 92: ...outputs you can enter the pulse control factor in terms of Internally several functions are able to trigger one digital output The active function will be displayed in the Mode section The following...

Страница 93: ...ed on nn pulse control factorfor pwm digital outputs in the range of 0 100 9 4 2 Abbreviations TAGs for Digital Outputs For a complete listing of the abbreviations TAGs for digital outputs refer to th...

Страница 94: ...tag of analog input manual setting of operating mode and input signal MODE auto normal operation external input triggers function of the DCU3 system manual manual operation input of input signal in ha...

Страница 95: ...evel can configured within 0 10 V 0 100 0 20 mA 0 100 4 20 mA 0 100 In the manual operating mode only the relative signal level 0 100 for the analog in puts is displayed or must be entered The assignm...

Страница 96: ...l operation locking Lowest priority controllers etc 9 6 1 Operating Display Column Entry Meaning I O Addr Tag Name AO 01 STIRR AO 02 AIRFL etc Display of tag of analog output manual input of operating...

Страница 97: ...nt Unassigned spare outputs have their physical channel assignment as TAG Example AOPnn Analog Output Process analog output for process 9 6 3 Special Notes The physical signal level of the analog outp...

Страница 98: ...ery correspond with the fermentor system to which the DCU3 system is assigned to Only authorized service personnel is allowed to change the settings of this menu 9 7 1 Operating Display Tag Entry Disp...

Страница 99: ...ce for connection of peripheral units such as pro tocol printers or a laboratory balance system The parameters for connection of a protocol printer to the DCU3 system can be entered via the func tion...

Страница 100: ...In addition a host computer can be connected via a se rial interface RS 232 available via the peripheral interface PERI You must enable the data transmission between DCU and host system via the REMOT...

Страница 101: ...letely which may occur after a software reset of the system Plug assignment plans of the host computer interface are described in details in the Techni cal Manual DCU system A detailed description of...

Страница 102: ...umber of stop bit PARITY even no Input of type of parity check ALARM Input of state of alarm function enable alarms are transmitted disable alarms will not be transmitted 9 10 2 Default Settings for P...

Страница 103: ...layed value or function required input PROTOCOL Selection of balance protocol Sartorius Protocol SARTORIUS all actual new balance systems Mettler Protocol METTLER MT SICS LEVEL 0 and previously suppli...

Страница 104: ...r on disable beeper off FAILTIME h m Input of power failure time FAILTIME in hours minutes for system behavior after restart The system will behave as follows power failure FAILTIME system continuous...

Страница 105: ...ring of malfunctions Prior to a system reset you should record your most important parameters and settings This will allow you to easily reconfigure your system according to your requirements This is...

Страница 106: ...Operators Handbook DCU3 System 9 Main function Maintenance BAEDCU3 Rev 4 6 0504 9 18...

Страница 107: ...terface The printer software offers the following possible protocols Trend line printout for 10 selectable process values with an adjustable printing interval and selectable statistical analysis Alarm...

Страница 108: ...onal records calib calibration data alarm limits of process value alarms MODE operation mode for record start selected records are printed stop interruption of record printout TYPE input of parameter...

Страница 109: ...ent range for the process values 10 3 1 Operating Display Tag Entry Displayed value or function required input Channel 1 6 Display of recorder channel Process Value Tag PV Input of process value Tag o...

Страница 110: ...Operators Handbook DCU3 System 10 Main Function Documentation BAEDCU3 Rev 4 6 0504 10 4...

Страница 111: ...the setting of controller parame ters PID etc the setting of interface parameters and the manual operation If a function is selected which is password protected then a numercal display for entering t...

Страница 112: ...word Field Entry Function required input PASSWORD 0 9 Enter the standard password Special Notes After a software reset the default setting for the standard password 9 is available again The multi leve...

Страница 113: ...tion Info i e such as System parameters Hotline Display Info Field Entry Function required input Software Vers Display of actual version of the implemented software Configuration Display of the instal...

Страница 114: ......

Страница 115: ...rm Messages Alarm Messages will be displayed in the second line of the touch display and if connected on a re mote terminal The messages include a short reference for the kind of alarm and in the righ...

Страница 116: ...rating Display Tag Entry Displayed value or function required input ACK Confirmation of single alarms ACK ALL MESSAGES Confirmation of all existing alarms ALARM MESSAGE OVERVIEW Display of all unackno...

Страница 117: ...perating Manual of fermentor Motor failure overheat protection of motor is acti vated let motor cool down before switch ing on fermentor again TEMP Sens failure Pt 100 in culture vessel is defective o...

Страница 118: ...lure occurred HH hours and MM minutes ago max interval of mains failure passed see Operating Behavior Confirm alarm with ACK nowl edge Printer not ready Printer protocol enabled but data transmission...

Страница 119: ...1st FIB XXX error code Check cable connection check peripheral device may be malfunctioning 2 FIB not inst 102 2nd FIB missing or installed incorrectly Check board address reset to delivery state sen...

Страница 120: ...6 175 The analog inputs AIP01 AIP17 of the 4th FIB are malfunctioning Send a claim note for the FIB 4 FIB AI17 32 175 The analog inputs AIP17 AIP32 of the 4th FIB of the analog input extension are are...

Страница 121: ...with ut most care If problems arise with the use of the DCU system malfunctions technical problems the user or the customer service should return a detailed description of the problem The operator or...

Страница 122: ...dosing counter acid pump delivered volume BASE dosing counter alkali pump delivered volume AFOAM dosing counter antifoam agent pump delivered volume SUBS process value nutrient solution pump AIRFL pr...

Страница 123: ...U switched on SUPON status signal from basic unit mains switch basic unit switched on 14 4 3 Digital Outputs Tag Displayed value or function required input HEAT status signal from culture vessel jacke...

Страница 124: ...ocuments Interface Parameters Baud rate see configuration documents Parity see configuration documents number of stop bits see configuration documents type of handshake software handshake Miscellaneou...

Страница 125: ...esentative of Sartorius BBI Systems GmbH or Sartorius AG for further support or write directly to Sartorius BBI Systems GmbH Dept FA Product engineering automation projects Schwarzenberger Weg 73 79 D...

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Страница 138: ...Operators Handbook DCU3 System 14 Supplement BAEDCU3 Rev 4 6 0504...

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Страница 150: ...Operators Handbook DCU3 System 14 Supplement BAEDCU3 Rev 4 6 0504...

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