REPLIGEN TangenX SIUS PD страница 1 Скачать руководство пользователя | Manualshive

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12

Identification

IF.PUG.019

Revision

R2

Approved

20-DEC-2018

TangenX™ SIUS™ PD Filter Plate

and 2-Bolt Clamp Assembly

USER GUIDE

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2
3
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Содержание TangenX SIUS PD

Страница 1: ...Page 1 of 12 Identification IF PUG 019 Revision R2 Approved 20 DEC 2018 TangenX SIUS PD Filter Plate and 2 Bolt Clamp Assembly USER GUIDE ...

Страница 2: ...ed herein or for incidental or consequential damages in connection with the furnishing performance or use of this material No part of this document may be photocopied reproduced or translated to another language without the prior written consent of Repligen Corporation For further information please contact Repligen Corporation at www repligen com 2017 Repligen Corporation All rights reserved The ...

Страница 3: ...ilibration 8 9 Cassette System Cleaning 8 10 Used TangenX SIUS PD Cassette Disposal 10 11 Unused TangenX SIUS PD Cassette Storage 10 12 Membrane Operating Characteristics 10 13 Chemical Restrictions 11 14 Repligen TangenX Standard Warranty 12 List of Tables Table 9 1 Recommended cleaning solutions 9 Table 12 1 Recommended crossflow rates 10 Table 12 2 Maximum operating pressures 10 Table 12 3 Air ...

Страница 4: ...Stainless Steel Compatibility c TangenX SIUS Packet Cassette Torque Range b 120 180 in lbs 14 20 N m Hydraulic Option No Hex Socket 11 16 CONSUMABLES 8 Filter Plate TFPLS LVFL d TFPLS SA08 c Polypropylene 9 Isolation Plate Polypropylene 10 TangenX SIUS PD LP1L J or K e LP2L J or K e L01L J or K 11 Gasket EPDM a Not Shown b Always check and re torque if necessary your holder prior to use c NOT COMP...

Страница 5: ...s Filter Plate Inserts are designed for single use Since Repligen does not recommend re use it is the responsibility of the end user to define a suitable cleaning protocol CASSETTE Product is packaged wet and must remain hydrated for optimal performance Keep bag sealed until cassette installation Section 6 Step 3 below TangenX SIUS PD cassettes are compatible with all TangenX cassette holders Cass...

Страница 6: ...into base plate If loose place a 1 8 drive pin into thru hole on threaded rod and turn clockwise 6 Filter Plate Installation 1 The steps from CLAMP SETUP are complete 2 Remove Filter Plate Insert FPI and Isolation Plate from outer carton if not already removed WARNING Wear gloves to avoid contamination 3 Using scissors carefully open the FPI bag and remove the FPI 4 Again using scissors carefully ...

Страница 7: ... Place a rinsed gasket flat against the bottom FPI ensure that the holes in the gasket line up with the holes in the manifold 3 Using scissors carefully open the cassette bag to remove cassette WARNING Each cassette is stored in 0 2M sodium hydroxide solution as a preservative Follow standard safety procedures for handling 0 2M sodium hydroxide including the use of gloves safety goggles and lab co...

Страница 8: ...o create a liquid tight seal but do not exceed the maximum torque limit for the 4BMC clamp WARNING The hex nuts should be checked for adequate torque PRIOR to every run using the procedure described herein In addition torque may change during processing as the cassettes may expand or contract with temperature changes Periodically check the torque of each nut and adjust as needed 8 Repligen highly ...

Страница 9: ... all valves open Cassettes are left in place during the system cleaning procedure to provide a flow path for the cleaning solution Alternatively the cassettes may be removed and replaced with a CIP spacer gasket see Figure 1 1 Upon completion of the cleaning cycle flush the system with WFI or DI water prior draining and discarding the cassettes Table 9 1 lists possible recommended cleaning solutio...

Страница 10: ...egrity and prevent microbial growth Below are critical factors to remember when storing unused TangenX SIUS PD cassettes Recommended storage temperature 4 C to 25 C longer than 7 days long term 50 C less than 7 days short term Do not freeze cassettes 12 Membrane Operating Characteristics Take care to use the membrane at the lowest pressure possible while still producing consistent permeate flow Al...

Страница 11: ... the following Pure aromatic and chlorinated hydrocarbons Ketones Polar aromatics Aliphatic esters CAUTION In the event that the cassette is subjected to any of the conditions listed below it is recommended that you perform both cassette integrity and water flux tests to ensure your cassette is not damaged Damage may occur as a result of the following Dropping on hard surfaces or other mechanical ...

Страница 12: ...shed catalogues and product literature may not be altered except by express written agreement signed by an officer of Repligen Representations oral or written which are inconsistent with this warranty or such publications are not authorized and if given should not be relied upon In the event of a breach of the foregoing warranty Repligen s sole obligation shall be to repair or replace at its optio...

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