27 400-12355-000 Rev. 03
KR2
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/ KMP
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TFF Systems
Setup and Operation
5.
Hardware Setup
Settings for the Automation Modes and general system parameters are entered into the
Hardware Setup window.
NOTE:
All hardware settings and other options can be entered in the system console under the
wrench icon. Please refer to section 7.10.5. The Feed and Permeate Status and Hold-up
Volumes can be entered in the Pump Mode screen on the console.
Feed and Permeate Status and Hold-up: volumes not currently measured on the scale are back-
calculated into the formula for endpoint control based on Concentration Factor and Diafiltration
Volumes.
Feed Status: Select ‘Empty’ if recirculation loop is empty upon start of automated process.
Select ‘Full’ if recirculation loop is full of liquid.
Permeate Status: Select ‘Empty’ if permeate side of the filter and permeate tubing is empty upon
start of automated process. Select ‘Full’ if permeate side of the filter and permeate tubing is full of
liquid.
Feed Hold-up: measure the amount of liquid in the feed holdup and enter the amount. Volume can
be measure by starting with an empty flowpath, closing the permeate line and measuring the
amount of liquid in the reservoir before and after running the system. The difference in the amount
of liquid is the recirculation holdup volume.
Permeate Hold-up: measure the amount of liquid in the permeate side of the filter plus the
permeate tubing and enter the amount.
Permeate Stop First: Permeate pump drive stops before main drive stops
Check Weight: Automated pump mode will not start if Feed Scale Weight is less than Initial
Concentration Weight, or if the Permeate Scale Weight is more than the Initial Diafiltration Weight.
