Labconco FreeZone 794801 Series, Руководство пользователя

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Chapter 4: Using Your Stoppering Tray Dryer
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Original instructions
Freeze Drying
Turn on the FreeZone Freeze Dryer. See Freeze Dryer User’s Manual for
complete instructions on operating the Freeze Dryer.Following the instructions for
the unit, this may be accomplished in either the auto or manual mode.
When the Freeze Dryer collector temperature is less than –40°C and the vacuum
has reached the desired level, the MANUAL mode set point temperature may be
adjusted or PROGRAM mode may be initiated. At no time during the primary
drying phase should the product temperature be allowed to rise higher than the
eutectic temperature.
The ice collecting coil temperature and the vacuum level should be monitored.
Higher than desired collector coil temperature or vacuum levels will inhibit or
ruin the freeze dry process.
Stoppering
The stoppering operation (when desired) is performed after the freeze dry process
is complete. To stopper, move the Stoppering control toward the “RAISE”
position. This action allows the bladder beneath the bottom shelf to inflate
causing the bottom shelf to rise. The vials on the shelf will then contact the
middle shelf causing it to rise and the top shelf will eventually be contacted and
rise. When all three shelves have raised and made contact with each other,
stoppers will be pressed into the vials. Monitor the stoppering process by looking
through the chamber door.
When all of the vials appear to be stoppered, move the Stoppering control to the
“LOWER” position. This opens the bladder to the vacuum pump, which will
cause it to deflate. Opening the vacuum release valve also deflates the stoppering
bladder. The Stoppering control should be left in the “LOWER” position when
not stoppering.
Vacuum Break/Backfilling
To open the chamber door, the vacuum must be released. To release the vacuum,
move the Vacuum Release valve to the “OPEN” position and turn off the vacuum
from the Home screen on the Freeze Dryer.
Air enters the vacuum chamber through the Back Fill port. When the sound of air
through the Back Fill port is no longer audible, the chamber door is ready to open.
To backfill the chamber with a gas, connect a cylinder of the desired gas to the
Back Fill port. The port will accept 1/8" tubing. The bottle must be equipped
with a regulator set to 15 psi maximum. The gas can be metered with the
Vacuum Release valve and chamber pressure monitored on the Freeze Dryer
control panel. Allow the vacuum pump to run for a few minutes while the gas
enters to permit the back fill gas to surround the freeze dried sample. When the