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Valve INV-907 Instructions 56-8101-01 Edition AE

Содержание AKTA Valve INV-907

Страница 1: ...Valve INV 907 Instructions GE Healthcare ÄKTA ...

Страница 2: ......

Страница 3: ... copy of the corresponding Declaration of Conformity is available on request The CE symbol and corresponding declaration of conformity is valid for the instrument when it is used as a stand alone unit or connected to other CE marked GE Healthcare instruments or connected to other products recommended or described in this manual and used in the same state as it was delivered from GE Healthcare exce...

Страница 4: ...4 Valve INV 907 Instructions 56 8101 01 Edition AE ...

Страница 5: ...Valve INV 907 Instructions 56 8101 01 Edition AE Contents 1 Introduction 7 2 Installation 9 3 Operation 11 4 Maintenance 15 5 Trouble shooting 17 6 Reference information 19 5 ...

Страница 6: ...6 Valve INV 907 Instructions 56 8101 01 Edition AE ...

Страница 7: ...mple loop injecting the sample onto the column washing the system pump The valve can also be used to switch between upflow and downflow in a column Features Completely swept flow path minimises eluent or sample memory effect Flow rates up to 100 ml min All wetted parts are plastic PEEK Safety WARNING When using hazardous chemicals take all suitable protective measures such as wearing protective gl...

Страница 8: ...8 Valve INV 907 Instructions 56 8101 01 Edition AE 1 Introduction ...

Страница 9: ... with two UniNet cables as a part of the UniNet 2 chain 2 Set the ID switch at the bottom to the required valve number 0 9 The number should correspond to that used in UNICORN Note All valves must have different numbers 3 Mount the valve vertically in the way it is shown in the user documentation of your ÄKTAdesign chromatography system 4 Apply an identification number from the labels supplied The...

Страница 10: ...g as follows Port Connect to 1 Column inlet 2 Sample loop or bottom tubing of Superloop 3 Injection port 4 Waste 5 Waste 6 Sample loop or top tubing of Superloop 7 Outlet of the pump 7 When used as an upflow downflow valve connect the valve as indicated in the user documentation of your ÄKTAdesign chromatography system ...

Страница 11: ...in System Control Manual Flowpath The valve can be set in 3 positions LOAD position 1 home position INJECT position 2 WASTE position 3 If the valve has not been activated it is in position 1 3 Operation 1 2 3 4 5 6 7 1 2 3 4 5 6 7 1 2 3 4 5 6 7 LOAD position 1 INJECT position 2 WASTE position 3 Column Sample syringe Pump Waste Column Pump Waste Column Pump Waste Waste ...

Страница 12: ...e injection fill port as described below Check the fill port nozzle is screwed into the fill port Note The thread is left handed 1 Loosely thread the fill port screw into valve port 3 2 Insert the injection needle 0 7 mm o d into the injection fill port 3 Tighten the fill port until the nozzle has formed a seal around the needle tip When the seal is adjusted correctly it feels as if you are penetr...

Страница 13: ...ge volume of buffer 5 the loop volume 3 Fill the sample loop carefully with buffer 4 Set the injection valve to position INJECT before taking out the syringe Note If the syringe is taken out when the injection valve is in position LOAD self drainage will occur and air will enter the sample loop 5 Load the syringe with the required volume of sample No more than half 50 a loop volume of sample shoul...

Страница 14: ...1 Set valve to position LOAD 2 Load the syringe with sample 2 5 times the loop volume 3 Gently load the syringe contents into the loop 4 Leave the syringe in position The sample will be injected onto the column when the valve is switched to INJECT in the method Note If the syringe is taken out before the sample is injected onto the column self drainage will occur and the loop will be emptied Empty...

Страница 15: ... plate and or when required distribution plate Cleaning in place Pump a cleaning or sanitizing agent through the valve The standard recommendation is to pump 1 M NaOH for 30 minutes and then wash out with buffer Changing channel plate and distribution plate WARNING NaOH is injurious to health Avoid spillage A replacement kit Valve Kit INV 907 is available see ordering information in Reference Info...

Страница 16: ...tal and to the right of the central tubing connection Using the Allen key tighten the 4 screws in turn a little at a time until the distribution plate is fixed to the valve body This symbol indicates that the waste of electrical and electronic equipment must not be disposed as unsorted municipal waste and must be collected separately Please contact an authorized representative of the manufacturer ...

Страница 17: ... horizontal External leakage 1 Check the tubing connections Tighten or replace if required Internal leakage Internal leakage are easy to detect at the small hole on the underside of the valve body 1 Internal valve parts may be worn Change channel plate and distribution plate according to section 4 High back pressure clogging 1 Do cleaning in place according to the instructions in section 4 2 Chang...

Страница 18: ...18 Valve INV 907 Instructions 56 8101 01 Edition AE 5 Troubleshooting ...

Страница 19: ...on existing The valve rotates the shortest way to the next position max 180 The material used in the switching parts ensures both long mechanical and chemical lifetime The valve housing contains no user replaceable items Technical specifications Operating data Max Flow rate 100 ml min Max Pressure 25 MPa 250 bar 3600 psi Back pressure 50 kPa at 100 ml min with water Leakage 0 1 μl min at 25 MPa pH...

Страница 20: ...of biomolecules except 100 ethylacetate 100 hexane and 100 tetrahydrofuran THF Power requirement 32 V DC 10 from the system pump Power consumption Up to 9 W UniNet 2 address 0 9 Inlet and outlet tubing UNF 10 32 2B Fingertights for capillary tubing 1 16 outer diameter Dimensions H W D 135 80 120 mm Weight 1 2 kg EMC Standards This device meets the requirement of the EMC Directive 89 336 EEC throug...

Страница 21: ...01 2 ml 1 18 1114 02 Superloop 10 ml 1 18 1113 81 Superloop 50 ml 1 18 1113 82 Superloop 150 ml 1 18 1023 85 Cable UniNet 0 7 m 1 18 1109 74 Mounting bracket 1 18 1109 11 Teflon tubing i d 1 8 o d 3 16 3 m 18 1112 47 Tubing connector for 3 16 o d tubing 10 18 1112 49 Ferrule for 3 16 o d tubing 10 18 1112 48 Stop plug 5 16 5 18 1112 50 Stop plug 1 16 5 18 1112 52 Union Luer female 1 16 male 2 18 1...

Страница 22: ...22 Valve INV 907 Instructions 56 8101 01 Edition AE ...

Страница 23: ...23 Valve INV 907 Instructions 56 8101 01 Edition AE ...

Страница 24: ...re Bio Sciences Corp 800 Centennial Avenue P O Box 1327 Piscataway NJ 08855 1327 USA GE Healthcare Bio Sciences KK Sanken Bldg 3 25 1 Hyakunincho Shinjuku ku Tokyo 169 0073 Japan Asia Pacific Tel 852 2811 8693 Fax 852 2811 5251 Australasia Tel 61 2 2899 0999 Fax 61 2 9899 7511 Austria Tel 01 576 0616 25 Fax 01 576 0616 27 Belgium Tel 0800 73 888 Fax 03 272 1637 Canada Tel 1 800 463 5800 Fax 1 800 5...

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