FagronLab PRO, Руководство пользователя

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FagronLab™ PRO – User Manual | 23
FagronLab™ PRO
Mixing programs
Pre-grinding
The pre-grinding process serves to wetten solids in the preparation of suspension with an active substance content < 2 %, allowing
a homogeneous distribution of active substances in an ointment foundation.
As an example, the incorporation of corticoids, antibiotics, fungicides or hormones in an ointment foundation. In order to ensure a
homogenous distribution, we recommend using the standard mixing blade.
First, load approximately 30 % of the foundation ground-covering in the jar and cover the micronized active substances with
foundation. The active substances have to be covered in the foundation in order to avoid powder residue sticking on the blade.
The jar bottom should be pushed up as far as possible to prevent incorporating air.
Please inspect the preparation for agglomerates or qualitative abnormalities after the pre-grinding process is completed. If
required, the pre-grinding process may be repeated.
Further processing of the compound should be prepared by using the program "Suspension < 2 %".
Suspension < 2 %
After finalising the pre-grinding process, both the remaining foundation and all active substances will be weighed in. Therefore
move the jar bottom by using a spatula all the way down to add the remaining components.
To incorporate air as little as possible push the movable jar bottom up until resistance is felt.
Suspension > 2 %
With the mixing program "Suspension > 2 %" solid substances of more than 2 % can be incorporated into foundation.
As an example, the incorporation of zinc oxide, salicylic acid or bismuth gallate in foundation. To ensure a homogeneous
distribution we recommend using the standard mixing blade.
For suspensions with ingredient content above 2 % pre-grinding process is not required.
In preparation, add 50 % of the required foundation ground-covering into the jar and the micronized solids to the middle. Add the
remainder of the base on top of the ingredients in order to avoid remaining powder sticking to the blades.
The jar bottom should be pushed up as far as possible to prevent incorporating air.
Compounds with a higher content of solids, e.g. pastes, warming of the compound during the mixing process may occur. This
temperature rise may be reduced applying cooled foundation or using a cooling cuff.