ELITechGroup MACRODUCT ADVANCED 3710 SYS, Руководство пользователя

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SECTION 1: INTRODUCTION
1.6 Macroduct Advanced Sweat Collector
Advantages of the Macroduct Advanced Sweat Collector
• By preventing any exposure to air, the collected sweat is not subject to condensate error.
• Sweat evaporation can only occur at the advancing meniscus in the plastic collecting duct. This
has been found by measurement to produce a negligible loss of 0.1 µL/h.
•
The operator can gauge the amount of sweat produced at any time, a unique and
unprecedented feature that eliminates guesswork in deciding the duration of the collection
period.
•
The patient has complete mobility during the collection period. (The collector can be over-
wrapped with an elastic bandage if needed.)
•
Collects sweat passively and automatically, driven by the natural hydraulic pressure of the
sweat gland to the skin surface.
Notes Regarding Sweat Rate
Official guidelines 1 specify a minimum sweating rate of 1g/m 2 /min for a sweat test to be
considered valid in the diagnosis of cystic fibrosis. This avoids the possibility of a false negative
when a partially functional CFTR ion channel returns chloride and other ions to the body during
sweating, but at an abnormally slow rate. The established volume to meet this rate with the
Macroduct Advanced is 15 µL within 30 minutes.
1. CLSI Sweat Testing:
Sample Collection and Quantitative Chloride Analysis; Approved Guideline—Third Edition.
CLSI
document C34-A3. Wayne, PA, Clinical and Laboratory Standards Institute; 2009.