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2.1

Safety precautions

Introduction

The safety precautions in this section are grouped in the following categories:

General precautions, on page 10

Flammable liquids and explosive environment, on page 11

Personal protection, on page 11

Installing and moving, on page 12

System operation, on page 13

Maintenance, on page 14

General precautions

WARNING

Only properly trained personnel may operate and maintain the
product.

WARNING

Do not operate the product in any other way than described in the
user documentation.

WARNING

Use only approved parts. Only spare parts and accessories that
are approved or supplied by Cytiva may be used for maintaining or
servicing the product.

2 Safety instructions

2.1 Safety precautions

10

 Chromaflow Packing Station 50, 100, 200, and 400 Operating Instructions 29046228 AD

Содержание Chromaflow 100

Страница 1: ...Chromaflow Packing Station 50 100 200 and 400 Operating Instructions Original instructions cytiva com...

Страница 2: ...Connectcompressedairsupply 48 4 5 3 Guidelinesforconnections 49 4 5 4 Groundingconnection 50 4 5 5 Connectacolumn 51 5 Operation 56 5 1 Prepareyour ChromaflowPackingStation 58 5 1 1 Finalactionsbefor...

Страница 3: ...5 1 Contactinformation 89 8 5 2 EuropeanUnionandEuropeanEconomic Area 90 8 5 3 Otherregulationsandstandards 91 8 6 HealthandSafetyDeclarationForm 92 8 7 Furtherinformation 94 Index 95 TableofContents...

Страница 4: ...s regu latoryinformation intendeduseofChromaflow PackingStation andalistofassoci ateddocumentation Inthischapter Section Seepage 1 1 Aboutthismanual 5 1 2 Importantuserinformation 6 1 3 Associateddocu...

Страница 5: ...ndividual ChromaflowPackingStation referto therelevantinformationinthedocumentationpackageprovidedwitheachproduct Contactyourlocal Cytiva representativeformoreinformation ifneeded Typographicalconvent...

Страница 6: ...urposes ChromaflowPackingStation isnotsuitableforoperationinapotentiallyexplosive atmosphereorforhandlingliquidsunderconditionsatwhichtheycouldbeflammable Prerequisites Inordertooperateyour Chromaflow...

Страница 7: ...otto proceeduntilallstatedconditionsaremetandclearlyunderstood NOTICE NOTICEindicatesinstructionsthatmustbefollowedtoavoid damagetotheproductorotherequipment Notesandtips Note A note is used to indica...

Страница 8: ...ChromaflowPackingStation are Document Abbrevia tion Contents PipingandInstrumenta tionDiagram P ID Schematicoverviewoftheentire processflow includingallcomponents andinstruments GeneralSpecification G...

Страница 9: ...resfor your ChromaflowPackingStation Thelabelsontheinstrumentandinformation regardingrecyclingarealsodescribed Inthischapter Section Seepage 2 1 Safetyprecautions 10 2 2 Labels 16 2 3 Emergencyprocedu...

Страница 10: ...ation on page 13 Maintenance on page 14 Generalprecautions WARNING Onlyproperlytrainedpersonnelmayoperateandmaintainthe product WARNING Donotoperatetheproductinanyotherwaythandescribedinthe userdocume...

Страница 11: ...alandbiologicalagents takeallsuitableprotec tivemeasures suchaswearingprotectiveclothing glassesand glovesresistanttothesubstancesused Followlocaland or nationalregulationsforsafeoperationandmaintenan...

Страница 12: ...sarefollowed itisthecustomers responsibilitytoguar anteethesafetyofthepersonnelworkingwiththeproduct CAUTION Lockwheels Thewheelsof ChromaflowPackingStation should belockedduringnormaluse Thewheelssho...

Страница 13: ...ecified columnmaximumpressure WARNING Operatinglimits Neverexceedtheoperatinglimitsstatedinthis documentandontheproductlabel WARNING Powerfailureofconnectedsystems Duringapowerfailureofa connectedsyst...

Страница 14: ...itisreactivated Asuddenpressureincreasemaycause ruptureofpipingconnectionsandconsequentleakage CAUTION Alwaysturnoffthecompressedairsupplybeforedisconnecting ChromaflowPackingStation fromthecolumn Mai...

Страница 15: ...resabovethespecifiedlimits WARNING Pressuremayremaininthecolumnandtubingforanextended periodaftershutdown Makesurethesystemisdepressurized beforeopeningordisconnecting WARNING Forcontinuedprotectionag...

Страница 16: ...ves Codeno Codenumberidentifyingtheproductsizeandtype Serialno Serialnumberoftheindividualproduct Yearofmanufacture Manufacturingyear Operatingtemperature TS Allowedfluidtemperaturerange Supplyairpres...

Страница 17: ...on page 18for furtherinformationregardingtheemergencystop WARNING Thepumphousingisunderspringpressure CAUTION Pressurecontrolvalveshallbesetto6barg forinstrumentairsupply Earprotectionmustbewornwhenev...

Страница 18: ...maflowPackingStation followinganemergencyshutdown Precautions WARNING Pressuremayremaininthecolumnandtubingforanextended periodaftershutdown Makesurethesystemisdepressurized beforeopeningordisconnecti...

Страница 19: ...vesselsthatareunderpressure Thisisdoneby openingvalvesanddisconnectinghosescarefully 4 Diagnoseandremedytherootcauseoftheproblem 5 Contact Cytiva iftheproblemcannotbesolved Restartafteremergencyshutdo...

Страница 20: ...hattheconditionthatcausedtheemergencystopiscorrected 2 ResettheEMERGENCYSTOPbuttonbyturningitclockwise 2 Safetyinstructions 2 3 Emergencyprocedures 20 ChromaflowPackingStation50 100 200 and400Operatin...

Страница 21: ...ttingpriortousingtheSTART RESETbutton toavoidanimmediatehighpressure increaseinthesystemwhenitisreactivated Asudden pressureincreasemaycauseruptureofpipingconnec tionsandconsequentleakage 2 Safetyinst...

Страница 22: ...esadescriptionofthe ChromaflowPackingStation Inthischapter Section Seepage 3 1 ChromaflowPackingStation maincomponents 23 3 2 Controlpanels 27 3 3 Flowchart 33 3 Systemdescription 22 ChromaflowPacking...

Страница 23: ...The ChromaflowPackingStation isfittedonaskidequippedwithlockablewheels Each ChromaflowPackingStation iscomprisedoftwopumpsandfourdiaphragm valvesthatarelocatedunderneathacabinetwithoperatingcontrolpa...

Страница 24: ...3 Systemdescription 3 1 ChromaflowPackingStation maincomponents 24 ChromaflowPackingStation50 100 200 and400OperatingInstructions29046228AD...

Страница 25: ...naboutairpressureandflowofbufferand slurry 2 Nozzlecontrol connectioninter face Panelforconnectingtocolumnautomaticnozzlesto allowthesetobecontrolledfroma Chromaflow PackingStation 3 Slurryinlettop SI...

Страница 26: ...y procedures on page 18 12 EMERGENCY STOP Buttontostopoperationimmediatelyinanemer gencysituation Forinformationaboutemergencyprocedures see Section 2 3 Emergency procedures on page 18 Note Please not...

Страница 27: ...sBandC andbetweencolumnSITandSIB Thelowercontrolpanelistheprimarypointforoperatingyour ChromaflowPacking Station Uppercontrolpanel 1 2 3 4 5 6 7 Theindicatorsandcontrolswitchesontheuppercontrolpanelar...

Страница 28: ...ptothebottomnozzleisopen Thetextontheuppercontrolpanelisexplainedinthefollowingtable Part Function A ConnectionfromSOTtotheCOLLECTIONtank B Inlettothe ChromaflowPackingStation that connectstothePACKIN...

Страница 29: ...2 3 4 5 6 7 8 Thetablebelowdescribesthelowercontrolpanelfunctions No Part Function 1 AIRSUPPLY PACKINGPUMP Controlstheamountofairsupplytothepacking pump Note This air supply control bypasses the FINEA...

Страница 30: ...to 0when the nozzle control function is not used 6 TOPNOZZLE Usedtomovethetopnozzletothefollowingpositions Run settheswitchtoRUN Pack settheswitchtoPACK Unpack settheswitchtoUNPACK Note Only applicab...

Страница 31: ...moreinformationseeSection 2 3 Emer gency procedures on page 18 4 FINEADJUST MENTPACKING PUMP Usedtomakefine scaleadjustmentstothepacking pumpairpressure 5 FINEADJUST MENT UNPACKING PUMP Usedtomakefine...

Страница 32: ...TTOM NOZZLE Usedtomovethebottomnozzletothefollowingposi tions Run settheswitchtoRUN Pack settheswitchtoPACK Unpack settheswitchtoUNPACK Note Only applicable for automatic nozzles 9 AIRSUPPLY UNPACKING...

Страница 33: ...ER SLURRY COLLECTION UNPACKING PUMP P 202 XV 021A XV 021C XV 022A XV 022C SOT SOB MPB MPT COLUMN SIT SIB A B C D EXTENT OF PACKING STATION PSV PSV Note Pressure safety equipment red must be installed...

Страница 34: ...SOTtotheCOLLECTIONtank B InletthatconnectstothePACKINGBUFFERtank C InletthatconnectstotheSLURRYtank COLLECTION Collectiontank canbeusedforwasteorrecirculation COLUMN Connectedcolumn D Outletfromtheunp...

Страница 35: ...MP P 202 Pumpsfluidsfromthecolumn XV 021A PACKINGBUFFERvalve XV 021C SLURRYvalve XV 022A SITvalve XV 022C SIBvalve 3 Systemdescription 3 3 Flowchart ChromaflowPackingStation50 100 200 and400OperatingI...

Страница 36: ...orpersonalsafetyduringthetransportation installation opera tion maintenanceandserviceofcolumns useprotectiveglasses andotherpersonalprotectiveequipmentappropriateforthe currentapplicationatalltimes Th...

Страница 37: ...ustbe performedinadherencewithlocalregulations Eveniftheinstructionsintheuserdocumentationandinstruction manualsarefollowed itisthecustomers responsibilitytoguar anteethesafetyofthepersonnelworkingwit...

Страница 38: ...evelandwithoutirregularities Inordertoallowconvenientworkingconditionsfortheoperator sufficientspace shouldbeprovidedonallsidesofthe ChromaflowPackingStation whenitis installedattheintendedproductionl...

Страница 39: ...Useapalletjackorforkliftwithaminimumcapacitytomatchtheemptyweightof theequipmentplusthetransportbox SeeSection 8 1 Specifications on page 81 regardingweightsanddimensions Makesurethatintendedopeningsa...

Страница 40: ...otheintendedprocesscontext Visualinspection Checkthefollowing Checkthatallequipmentisenclosedinthecrateaccordingtothepackinglist Checkthattheequipmentforanyapparentdamage Documentanyfounddamage carefu...

Страница 41: ...emarkedbolts fasteningthebeamsontheoutsideofthecrate indicatedbyarrowsinthe image 4 Carefullyremovethetopsupportbeamsfromthecrate Tip When removing the screws on the outside panel of the crate a secon...

Страница 42: ...rkedboltsfromthebottomfrontsupportbeam indicated byarrowsintheimage holdingthe ChromaflowPackingStation inplace 4 Installation 4 3 Unpackfromthecrate 42 ChromaflowPackingStation50 100 200 and400Operat...

Страница 43: ...owingillustration NOTICE Placeasoftmaterialbetweentheforksoftheforkliftand the ChromaflowPackingStation frameduringlifting operationstohelppreventdamagetothesurfaces This willminimizetheriskofrusting...

Страница 44: ...pmentforliftingwithtelphersorsimilarequipment Liftbyplacingliftingequipmentunderthelowerpartof theframe 7 Placethe ChromaflowPackingStation onalevelsurface 4 Installation 4 3 Unpackfromthecrate 44 Chr...

Страница 45: ...hewheelbrakesreleased Afterpositioningthesystematitsdesignatedlocation lockthewheelsbypressing downtheflapasshowninthefigurebelow Unlockthewheelsbypressingupthe flap Ifthefloorqualitydoesnotallowrolli...

Страница 46: ...9 4 5 4 Groundingconnection 50 4 5 5 Connectacolumn 51 Precautions CAUTION Theproductmaybepartlyfilledwithdenaturedalcohol 18 C2H5OH ethanol 2 C3H7OH isopropanol and80 H2O water atdelivery Thedenature...

Страница 47: ...llyassembled The Chromaflow PackingStation isequippedwithwheelsthatallowittobeeasilyrolledtoitsdesig natedlocationofuse Afterthe ChromaflowPackingStation isinpositionandthewheelsarelocked the pneumati...

Страница 48: ...e ChromaflowPackingStation airinlet AIRINLET Chromaflow sizes50 100 and200 Chromaflow size400 2 Makesurethatthepressureregulatorforthecompressedairthatisinside thecabinetissettothecorrectbargpressuref...

Страница 49: ...ersshallbelocatedasclosetothepackingstationas possible onthesamefloorofthebuilding andarrangedsothatbackpressureand suctionheightremainswithinsystemspecificationlimits Keepthetubinglengthsasshortaspos...

Страница 50: ...ndingpointislocatedononeoutercornerof theskid asshowninthefollowingillustration Thelocationofthegroundingpointis alsoindicatedontheskidbyagroundinglabel Agroundingkitisincludedwiththedeliveryofyour Ch...

Страница 51: ...mentsinthecolumnandsystemOperating Instructions NOTICE Thesuggestedconnectionschemesareofageneralnature Users maywishtoaltertheconfiguration dependingonspecificneeds If thereisanyquestionaboutsafetyco...

Страница 52: ...t on page 33 NOTICE Thepressuresafetyequipmentindicatedinredinthediagram aboveisnotprovidedaspartofthe ChromaflowPackingStation delivery Thediagramindicatestherecommendedplacementof suitablepressuresa...

Страница 53: ...n addi tion for a smooth transition from one diameter to another always use conical reducers Connecttanks Makethefollowingconnectionsbetweenthetanksandthe ChromaflowPacking Station Step Action 1 Conne...

Страница 54: ...on 1 Installpressuresafetyvalves PSV ontheMPTandMPBports Thevalves shouldhavethesameinnerdiameterasthecolumninlet outlet 2 Connectapressuregauge P recommendedrange0to6bar toMPTafter thepressuresafetyv...

Страница 55: ...ablepressuresafetyequipmenttoprotectthecolumnfrom exposuretooverpressureorvacuum Step Action 1 Installpressuresafetyvalves PSV ontheMPTandMPBports Thevalves shouldhavethesameinnerdiameterasthecolumnin...

Страница 56: ...steps in the following sections refer to the use of a pressure gauge These particular steps are part of a general procedure suggested by Cytiva although modifications can be made to these instruction...

Страница 57: ...onsintheuserdocumentationandinstruction manualsarefollowed itisthecustomers responsibilitytoguar anteethesafetyofthepersonnelworkingwiththeproduct WARNING Forcontinuedprotectionagainstinjuryrisksdueto...

Страница 58: ...ation istakenintooperation makesurethatall proceduresinthefollowingchaptersandsectionshavebeenperformed Chapter 4 Installation on page 36and Section 6 1 User maintenance schedule on page 66 Inthissect...

Страница 59: ...ChromaflowPackingStation totheinletandoutlet tanks andfromyour ChromaflowPackingStation tothecolumn isproperly connectedinaccordancewiththerespectiveinstructions Checkthatalltubingisingoodconditionand...

Страница 60: ...rprimingyour ChromaflowPackingStation andthe connectedcolumn Formoreinformationaboutcolumnpriming refertotheuser documentationforyourcolumn Iffurtherinstructionsareneeded pleasecontactyourlocal Cytiva...

Страница 61: ...recautions WARNING Usecolumnsthatwithstandexpectedpressures Alwaysuse appropriatepressurealarms pressureventsorrupturediscs and safetyequipment Ifnot thecolumnsmightrupture resultingin injury NOTICE W...

Страница 62: ...reneeded please contactyourlocal Cytiva representative Emptythecolumn Whenemptyingacolumn theconnectionfromtheCOLLECTIONtanktothecolumn mustenableafreeflowofairtoavoidunder pressureinthecolumn Toempty...

Страница 63: ...raphyresincanpreventthe membranesfrommovinginsidethepump Disconnect ChromaflowPacking Station Followtheprocedurebelowtodisconnectyour ChromaflowPackingStation fromthe column Step Action 1 Cleanyour Ch...

Страница 64: ...informationaboutorderingspareparts contactyourlocal Cytiva representative Inthischapter Section Seepage 6 1 Usermaintenanceschedule 66 6 2 Cleaning 68 6 3 Storage 76 Precautions WARNING Pressuremayrem...

Страница 65: ...T LOTO Beforeanymaintenanceor decommissioningworkisperformedonthesystem makesure that thesystemisemptyanddepressurized thesystemisdisconnectedfromprocessfeed electricalpower andpneumaticsupply thesyst...

Страница 66: ...k PleasecompletethechecklistintheOn Site Service Health and Safety Declaration FormortheHealth and Safety Declaration Form for Product Return or Servicing dependingonwhethertheinstrumentisgoingtobeser...

Страница 67: ...ressure Maintenanceannuallyorasneeded Thetablebelowlistsmaintenanceactionsthatarerequiredannuallyorasneeded Component Action Pump Replaceallwearandtearparts Refertothesystemdocumenta tionfordetails 6...

Страница 68: ...aths Thisresultsinapressureincrease orpreventsthe pumpfromstartingduetothatsettledchromatographyresinpreventsthe membranesfrommovinginsidethepump Formoreinformationaboutcleaningtheconnectedcolumn refe...

Страница 69: ...columnisproperlydecontaminatedandsanitizedbeforemainte nanceorservice WARNING Flammableliquids Thisproductisnotapprovedforhandling liquidsunderflammableconditions Makesuretouseliquidsonly undercondit...

Страница 70: ...pper control panel on page 27 Connections Step Action 1 Connectapieceofflexibletubing A fromSITtotheCOLLECTIONtank or directittowaste 2 ConnectapieceofflexibletubingfromSIBtoSOB 3 Connectapieceofflexi...

Страница 71: ...esselC 2 OpeninletCandoutletSIT 3 Startthepumpatmax50 speedandflushtheSITline removingany residualresinparticles Useabout25to50liters 4 OpenoutletSIBtoflushtheSIBline Useabout25to50liters Result Rinsi...

Страница 72: ...ndoutletSIT 3 Startthepumpatmax50 speedandflushtheSITlinewithCIPbuffer Use about25to50liters 4 OpenoutletSIBtoflushtheSIBlinewithCIPbuffer Useabout25to50 liters Result CIPbufferwillflushtheSIBlineincl...

Страница 73: ...SIT 3 Startthepumpatmax50 speedandflushtheSITlinewithrinsingbuffer Useabout25to50liters 4 OpenoutletSIBtoflushtheSIBlinewithrinsingbuffer Useabout25to50 liters Result RinsingbufferwillflushtheSIBlinei...

Страница 74: ...liters 4 OpenoutletSIBtoflushtheSIBlinewithstoragebuffer Useabout10to20 liters Result StoragebufferwillflushtheSIBlineincludingtheunpackingpump 5 OpeninletBandstopthepumpwhenvesselBisempty 6 Closepack...

Страница 75: ...ackingStation togetherwiththeconnectedcolumn OpeninletCand outletSITtocleantherestofthepackingstationtogetherwiththeconnectedcolumn Note For explanation of the image text see Upper control panel on pa...

Страница 76: ...g andlowenoughto preventevaporation Short termstorage Theprocedureforshorttermstorageisdescribedbelow Thisprocedureisapplicable forstoragedurationsuptoonemonth Step Action 1 Performcleaningasdescribed...

Страница 77: ...beintherange4 Cto30 Candstable Theairhumidityandairtemperaturedifferencesshouldbekeptaslowas possibletopreventcondensationandcorrosion Note To prevent microbial growth and evaporation of the storage s...

Страница 78: ...oinletoroutletvalveopen Checkvalves Impropercleaningleavingresintosedimentinthepump Ifnoneoftheabove contact Cytiva servicepersonnel Littleorno flow Checkthatconnectedinletisactuallyused Inletcontaine...

Страница 79: ...ectionoutlinestroubleshootingforvalverelatedissues Problem Possiblecause correctiveaction ChromaflowPacking Station doesnotfunc tionatstart Valvesmightnotbeworking Checkthat compressedairsupplyissuffi...

Страница 80: ...n abouthowtoobtainsupporttraining serviceandsparepartsisalsodescribed Inthischapter Section Seepage 8 1 Specifications 81 8 2 Chemicalresistance 85 8 3 Noiselevel 86 8 4 Recyclinginformation 87 8 5 Re...

Страница 81: ...to7barg 6to7barg 6to7barg 6to7barg Airconsumption Airflow500 NL min Airflow1000 NL min Airflow1250 NL min Airflow2000 NL min Ingressprotec tionEN60529 IP55 IP55 IP55 IP55 Operating temperature 4 Cto30...

Страница 82: ...cribesthematerialsusedinconstructionof ChromaflowPacking Station Parameter ChromaflowPackingStation Valvebodies Material 316L Wettedpart Yes Valvediaphragms Material EPDM Wettedpart Yes Pumphousings M...

Страница 83: ...1mm 1 5 34 8 mm 1 5 34 8 mm 2 5 60 2 mm Flangetypeandsize 1 5 TC50 1 5 TC50 1 5 TC50 2 5 TC78 InletSOB Dimension o d i d 1 22 1mm 1 22 1mm 1 5 34 8 mm 2 47 5mm Flangetypeandsize 1 5 TC50 1 5 TC50 1 5...

Страница 84: ...50 Volume 100 Volume 200 Volume 400 InletBtoSIT Includingpacking pump 0 72L 1 7L 3 7L 10 8L InletBtoSIB Includingpacking pump 0 86L 1 8L 4 3L 12 1L SOBtoInletD Includingunpacking pump 0 72L 1 5L 3 7L...

Страница 85: ...ighconcentrationsofstrongacids Listofallowedchemicals WARNING Non flammableconditions Someofthechemicalsusedwiththe productmaybeflammableundercertainconditions Makesureto usechemicalsonlyunderconditio...

Страница 86: ...imummeasurednoiselevelfor ChromaflowPackingStation is85dB A Note The maximum noise level of individual units may vary slightly CAUTION Useearprotectionwheneverworkingclosetothesysteminopera tion 8 Ref...

Страница 87: ...ommissioningandall localregulationsshallbefollowedwithregardtoscrappingoftheequipment Disposal generalinstructions Whentakinga ChromaflowPackingStation outofservice thedifferentmaterialsmust beseparat...

Страница 88: ...tapplytotheproduct Inthissection Section Seepage 8 5 1 Contactinformation 89 8 5 2 EuropeanUnionandEuropeanEconomicArea 90 8 5 3 Otherregulationsandstandards 91 8 Referenceinformation 8 5 Regulatoryin...

Страница 89: ...information Thetablebelowsummarizestherequiredmanufacturinginformation Requirement Information Nameandaddressofmanufacturer CytivaSwedenAB Bj rkgatan30 SE75184Uppsala Sweden Telephonenumberofmanufactu...

Страница 90: ...ththeproduct acopyoftheEUDeclarationofConformityisavailable onrequest CEmarking TheCEmarkingandthecorrespondingEUDeclarationofConformityisvalidforthe instrumentwhenitis usedaccordingtotheOperating Ins...

Страница 91: ...irementsfromUnitedStatesPharmacopeia BiologicalReactivityTests InVivo 21CFR177 Indirectfoodadditives Polymers Additionaldesignconsiderations Foradditionaldesignconsiderations suchasASME BPE GMPandcGMP...

Страница 92: ...is may require customer to move equipment from normal operating location prior to Cytiva arrival Consumables such as columns or gels have been removed or isolated from the instrument and from any area...

Страница 93: ...taminatedprior to service return Provide a telephone number where Cytiva can contact you for additional information concerning the system equipment Telephone No Liquid and or gas in equipment is Water...

Страница 94: ...Sparepartsandaccessories Yourlocal Cytiva representativewillbeabletosuggestrecommendedsparepartsand accessories Remainingaspects Contactyourlocal Cytiva representativeforadviceregarding Training Serv...

Страница 95: ...turinginformation 89 Methodoptimization 94 MPB 28 34 MPT 28 34 N Notesandtips 7 Nozzlecontrol 26 O Onsiteservice 92 Operation 56 Orderinginformation 94 P Prerequisites 6 Pressuregauge 54 Pressuresafet...

Страница 96: ...7 long term 77 short term 76 Systemdescription 22 T Training 94 Transport 39 45 inthecrate 39 unpacked 45 Troubleshooting 78 Typographicalconventions 5 U Uppercontrolpanel 27 W Wettedmaterials 94 Inde...

Страница 97: ...Pageintentionallyleftblank...

Страница 98: ...Cytiva Allotherthird partytrademarksarethepropertyoftheirrespectiveowners 2020 Cytiva AllgoodsandservicesaresoldsubjecttothetermsandconditionsofsaleofthesupplyingcompanyoperatingwithintheCytiva busin...

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