1000DF00741 Issue 5
49/52
Alaris™ PK Plus Syringe Pump
Profiles from TCI Mode
Predicted vs Ideal Concentration
Diprivan 1% Marsh Model BD 50ml Syringe
Diprivan 2% Marsh Model BD 50ml Syringe
• Patient Age: 40 Years
• Patient Weight: 60kg
• Drug Concentration: 10mg/ml
• Plasma Concentration Accuracy: +0.2%
• Patient Age: 40 Years
• Patient Weight: 60kg
• Drug Concentration: 20mg/ml
• Plasma Concentration Accuracy: -0.3%
Pr
edic
ted P
lasma C
onc
en
tr
ation (ng/ml)
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
0
5
10
15
20
25
30
35
40
45
50
55
60
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
Ideal P
lasma C
onc
en
tr
ation (µg/ml)
Pr
edic
ted P
lasma C
onc
en
tr
ation (ng/ml)
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
0
5
10
15
20
25
30
35
40
45
50
55
60
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
Ideal P
lasma C
onc
en
tr
ation (µg/ml)
Time Interval (mins)
Time Interval (mins)
Remifentanil Minto Model BD 5ml Syringe
Remifentanil Minto Model BD 50ml Syringe
• Patient Age: 75 Years
• Patient Weight: 65kg
• Patient Height: 175cm
• Patient Gender: Male
• Drug Concentration: 50µg/ml
• Plasma Concentration Accuracy: +0.2%
• Patient Age: 75 Years
• Patient Weight: 65kg
• Patient Height: 175cm
• Patient Gender: Male
• Drug Concentration: 50µg/ml
• Plasma Concentration Accuracy: +0.5%
Pr
edic
ted P
lasma C
onc
en
tr
ation (ng/ml)
0.0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
4.0
0
5
10
15
20
25
30
35
40
45
50
55
60
0.0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
4.0
Ideal P
lasma C
onc
en
tr
ation (ng/ml)
Pr
edic
ted P
lasma C
onc
en
tr
ation (ng/ml)
0.0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
4.0
0
5
10
15
20
25
30
35
40
45
50
55
60
0.0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
4.0
Ideal P
lasma C
onc
en
tr
ation (ng/ml)
Time Interval (mins)
Time Interval (mins)
Sufentanil Gepts Model BD 50ml Syringe
• Drug Concentration: 5.0µg/ml
• Plasma Concentration Accuracy: +3.1%
Pr
edic
ted P
lasma C
onc
en
tr
ation (ng/ml)
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
0.40
0
5
10
15
20
25
30
35
40
45
50
55
60
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
0.40
Ideal P
lasma C
onc
en
tr
ation (ng/ml)
Time Interval (mins)
