16
Phaser 3400 Personal Laser Printer
Material Safety Data Sheet
Section III - Toxicology and Health Information
This toner material has been evaluated by Xerox Corporation. The toxicity data noted
below is based on test results of similar reprographic toner material
s
Additional Information:
The results obtained from a Xerox-sponsored Chronic Toner
Inhalation Study demonstrated no lung change in rats for the lowest (1 mg/m
3
)
exposure level (i.e. the level most relevant to potential human exposure). A very
slight degree of fibrosis was noted in 25 percent of the animals at the middle
(4 mg/m
3
) exposure level, while a slight degree of fibrosis was noted in all the
animals at the highest (16 mg/m
3
) exposure level. These findings are attributed to
"lung overloading," a generic response to excessive amounts of any dust retained in
the lungs for a prolonged period. This study was conducted using a special test toner
to comply with EPA testing protocol. The test toner was ten times more respirable
than commercially available Xerox toner, and would not be functionally suitable for
Xerox equipment.
1
XEL - Xerox Exposure Limit
N.A. - Not Applicable
N.E. - None Established
N.D. - Not Determined
Oral LD
50
:
>5 g/kg (rats) practically non-toxic.
Dermal LD
50
:
>5 g/kg (rabbits) practically non-toxic.
Inhalation LC
50
:
>5 mg/l (rats, 4 hr exposure) practically non-toxic.
>20 mg/l (rats, calculated 1 hr exposure) non-poisonous,
Eye Irritation:
Not an irritant.
Skin Sensitization:
Not a sensitizer.
Skin Irritation:
Not an irritant.
Human Patch:
Non-irritating/non-sensitizing.
Mutagenicity:
No evidence of mutagenicity detected in Ames Assay.
Carcinogens:
None present
Aquatic LC
50
:
>1000 mg/l (fathead minnows/rainbow trout) non-toxic.
TLV:
10mg/m
3
(total dust)
PEL:
15 mg/m
3
(total dust)
5 mg/m
3
(respirable dust)
STEL
N.E.
Ceiling:
N.E.
XEL
1
2.5 mg/m
3
(total dust)
0.4 mg/m
3
(respirable dust)
