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P.A.M.

PRESSURE APPLICATION MEASUREMENT

Cat. No.

3 8 5 0 0

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Summary of Contents for PAM

Page 1: ...P A M PRESSURE APPLICATION MEASUREMENT Cat No 3 8 5 0 0...

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Page 3: ...WARNINGS WHICH MUST BE FOLLOWED TO ENSURE SAFE OPERATION AND TO RETAIN THE INSTRUMENT IN SAFE CONDITIONS SERVICE AND ADJUSTMENTS SHOULD BE CARRIED OUT BY QUALIFIED PERSONNEL AUTHORIZED BY UGO BASILE...

Page 4: ...r measuring mechanical pain threshold in experimental joint hypersensitivity models in rodents The PAM device has been designed and validated specifically for the mechanical stimulation and assessment...

Page 5: ...R small TRASDUTTORE small 38500 1 SOFTWARE SOFTWARE 38500 323 1 EXTERNAL TRIGGER SWITCH TRIGGER ESTERNO 52010 325 1 USB LEAD CAVO USB OPTIONAL 38500 006 0 PAW TRANSDUCER TRASDUTTORE DA ZAMPA DATE Seri...

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Page 7: ...T TIME OPERATION 7 4 2 ROUTINE OPERATION OF THE INSTRUMENT 10 4 2 1 TURNING THE INSTRUMENT ON 10 4 2 2 AUTOMATIC DIMMING OF THE DISPLAY 10 4 2 3 MENU OPERATION 10 4 2 4 TURNING THE INSTRUMENT OFF 11 4...

Page 8: ...NLOADED DATA 24 6 5 EXCEL FILES 26 7 MAINTENANCE 26 7 1 LONG INACTIVITY 26 7 2 CUSTOMER SUPPORT 27 8 ORDERING INFORMATION 27 9 BIBLIOGRAPHY 28 9 1 METHOD PAPER 28 9 2 OTHER PAPERS MENTIONING UB PAM 28...

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Page 10: ...UGO BASILE ITALY Page iv CONTENTS...

Page 11: ...transducer is mounted on the operator s thumb so that routine procedures may be employed to examine and test the joint concerned The completion of each test may be indicated by the operator either by...

Page 12: ...ce applicator is also available to measure pain threshold in paws and muscles see also paragraph 2 3 Figure 2 Paw Transducer 2 INSTRUMENT DESCRIPTION The 38500 is composed of 1 Handheld Electronic Uni...

Page 13: ...ree buttons below the display as soft buttons whose functions change at different stages of the PAM program The lower line of PAM s 4 by 20 character display is normally used to indicate the current f...

Page 14: ...y including muscles and paws or for other joints such as the ankle Each transducer contains a memory chip which identifies the type of transducer and its specific characteristics including all relevan...

Page 15: ...ing list to hand and visually inspect the instrument as soon you take it out of the packaging Use the Check List supplied If the instrument is damaged or after having tested it fails to meet rated per...

Page 16: ...the PAM Software The software provided with PAM should be installed on a suitable Windows PC running Windows Vista or XP First install the software by double clicking on the Set up exe file follow the...

Page 17: ...rantee a consistent performance of the test When using the PAM we can envisage two main potential sources of experimental variability the first is the animal emotional state which can be overcome by p...

Page 18: ...and then displays Apply gentle1 force to the transducer The display changes to typically For as long as the force is applied steadily the Force value will indicate the applied force in gf and the Time...

Page 19: ...each measurement Date Time Progressive number of the measurement Automatic or Foot Pedal measurement mode Peak Force Peak Time are shown and the measurements can be browsed by simply pressing Next Pr...

Page 20: ...4 2 2 Automatic dimming of the display The display backlight may be configured to dim automatically in most menus if no soft button is pressed during a preset period which may be set between 2s and 29...

Page 21: ...ault setting is never PAM will also switch itself OFF automatically if the battery voltage falls below a critical level 4 3 Main Menu The Main Menu is the first menu which appears when PAM is switched...

Page 22: ...ically by releasing the pressure on the transducer at the end of the test Auto Measurement 2 The transducer is the Large transducer with a full scale force measurement of 1500gf The warning sound abov...

Page 23: ...dicates the total length of the measurement The user must choose whether to Reject or Accept the results of the test If the result is rejected the user is given the option to finish making measurement...

Page 24: ...on the assumption that future measurements will be similar in length to those already stored The number of tests that can be stored strongly depends on the duration of each test Press Return to return...

Page 25: ...PAM These include options related to the measurement process such as whether the measurement is ended automatically by removing the applied force or manually by pressing the foot trigger switch but al...

Page 26: ...rm or only the peak value store waveform Ask whether the test is on Left or Right Do not Use Subject Numbers Do not only use Test number Use the applied force rate meter during tests Do not only use T...

Page 27: ...will be retained but PAM may not be used until it is connected to an active PC or a USB power adapter using the USB lead provided Clearly it is not advisable to allow the battery to drop to this criti...

Page 28: ...ustment ranges and default values Configuration flags which may be set or cleared Whether each measurement is ended automatically on the force level default or by pressing the foot pedal Whether every...

Page 29: ...om 1s to 29s in steps of 1s or never with a default value of never The target force rate which is the ideal rate at which the stimulus force should be applied The date and time settings of PAM s inter...

Page 30: ...ncludes changing the slope of the PAM target rate which is in fact from control unit see paragraph 4 5 Connect the PAM device to the PC using the supplied USB cord then run the Ugo Basile PAM Software...

Page 31: ...ft side is a visual guide during the experiments The operator should practice trying to match the applied force yellow line with this blue line of the display As you can see the yellow is the actual f...

Page 32: ...nge the slope on the visual display graphic side of the software one must return to the PAM controller toggle through the selected menus to reach the proper instructions When the rate of application o...

Page 33: ...ry make some new measurements and Accept them Next one the PAM controller select Transfer Data to PC from the PAM Measure menu of the PAM device The traffic lights on the PAM Software will show green...

Page 34: ...009 will be found in the folder C PAM Data 090723 Individual files containing the downloaded data are named automatically according to the date as above followed by two letters which progress from AA...

Page 35: ...s until the software shows the required test If the left or the right mouse button is clicked in the display area of the graph the vertical white cursor line is displayed and the force and time relati...

Page 36: ...me as the corresponding PAM data file and is stored in the same folder The data in the Excel file consists of columns for measurement number peak force and peak position filled with the values for eac...

Page 37: ...t to our factory for repair we recommend you to contact our service department to obtain a return authorization number R A N and shipping packing instructions We may not be held responsible for damage...

Page 38: ...or Detection of Primary Mechanical Hyperalgesia in Rat and Mouse Antigen Induced Knee Joint Arthritis Methods Findings in Exp Clinical Pharmacol 32 8 581 589 2010 T Schwagarus et al A New Method for M...

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