Thermo Scientific Applied Biosystems GeneChip 645 User Manual Download Page 6

Chapter 1 

The Hybridization Oven 645

Safety information

6

GeneChip

 Hybridization Oven 645 User Guide

1

Safety information

These instructions contain important operating and safety information. You must 

carefully read and understand these instructions before using the hybridization oven.

Applied Biosystems has designed the hybridization oven to optimize function, 

reliability, safety, and ease of use. It is your responsibility to install and use the 

hybridization oven properly. 

Follow these safety instructions regarding the hybridization oven:

• This equipment is for indoor use only.
• Connect the unit to a properly grounded electrical outlet of the correct voltage 

and current handling capacity. Check the nameplate on the back of the unit for the 

voltage and current rating.

• Do not remove or modify the grounded power plug. Use only properly grounded 

outlets to avoid a shock hazard.

• If replacing fuses, note that the oven employs double pole fusing. The power 

entry module, located on the rear panel of the unit, contains two fuses, one for 

each side of the AC power circuit. Replace these only with 5x20 mm F6.3A (fast 

acting) 250V rated fuses, as marked on the rear panel of the oven. (See 

"Replacing 

the fuses" on page 22

.)

• Disconnect the unit from the power outlet before performing any cleaning, 

maintenance, or service.

• The power cord is the disconnect device. Do not position the equipment so that it 

is difficult to operate the disconnecting device.

• Always verify that the rotisserie has stopped turning before reaching into the 

oven.

• The interior of the oven and its contents can reach temperatures that can cause 

burns. Avoid immediate contact with the oven interior upon opening the door, or 

wear protective gloves. The interior of the unit will remain hot without visual 

indication for some time after the door is open or power is switched off.

• If you plan to use the unit with any procedure that will give off fumes, be sure to 

operate the unit in a fume hood or with proper ventilation.

• The hybridization oven is not intended for use with flammable materials. If used 

with flammable materials, fire or explosion hazard may result.

• If radioactive materials are used in processing, user must comply with all 

regulations regarding the acquisition, use, and disposal of such materials.

• Do not continue to use the oven if the temperature or rotisserie controllers fail, as 

evidenced by errors E01 through E12 being displayed (see the section, 

"Error 

codes and troubleshooting" on page 21

). Contact Thermo Fisher Scientific 

Technical Support.

• Use appropriate hand and eye protection when handling hazardous chemicals.

CAUTION!  

If you use this instrument in a manner not specified by the 

manufacturer, the protection provided by the equipment may be impaired and 

the warranty may be voided.

WARNING!  

The oven weight is approximately 67 pounds (30 kg). To avoid 

injury, use 2 persons when lifting the oven.

Summary of Contents for Applied Biosystems GeneChip 645

Page 1: ...For Research Use Only Not for use in diagnostic procedures GeneChip Hybridization Oven 645 USER GUIDE Catalog Numbers 00 0331 Publication Number 08 0255 Revision E...

Page 2: ...INCLUDING YOUR USE OF IT Important Licensing Information This product may be covered by one or more Limited Use Label Licenses By use of this product you accept the terms and conditions of all applic...

Page 3: ...ing the rotisserie 16 Unloading the rotisserie 19 Communicating with the oven 20 Serial communication 20 Oven maintenance 22 Cleaning 22 Replacing the fuses 22 GeneChip Hybridization Oven 645 specific...

Page 4: ...en include Programmable temperature range from 30 0 C to 70 0 C Programmable rotation rate range from 10 rpm to 80 rpm Keypad programming Excellent temperature accuracy and uniformity Ergonomic design...

Page 5: ...e motor speed pause the motor or jog the motor 1 Press the UP or DOWN button until the set point blinks to access the set point 2 Press the UP or DOWN button to set the speed rpm 3 Press PAUSE to paus...

Page 6: ...onnect device Do not position the equipment so that it is difficult to operate the disconnecting device Always verify that the rotisserie has stopped turning before reaching into the oven The interior...

Page 7: ...luded in each box Red Part No 90 0356 Green Part No 90 0357 Purple Part No 90 0358 White Part No 90 0359 Eight spring steel carrier retaining clips Part No 10 0458 RS232 communications cable 5 meters...

Page 8: ...ridge preparation loading and unloading cartridge carriers Avoid extreme ambient temperatures and locations close to heaters or air conditioning vents Keep the oven dry avoid locations close to sinks...

Page 9: ...ntact with the interior or wear protective gloves 5 To close the door swing it shut and press the door until it latches Normal operation will resume Table 2 Rear panel items Item What it does How to u...

Page 10: ...d is equipped with a rubber foot Figure 2 The other end is equipped with a gear Figure 5 3 Place the rotisserie into the oven with the rubber mounted shaft end on the left Figure 4 4 Insert the shaft...

Page 11: ...end of the axle into the right side drive socket Figure 5 Turn the rotisserie until the axle clicks into place Release the rotisserie to allow the shaft to be seated into the socket Gently rotate the...

Page 12: ...atches the electrical supply employed in your location NOTE Ovens shipped from the factory have a small label covering the power entry receptacle warning the user to select the proper voltage The oven...

Page 13: ...ical power outlet Figure 8 Operating the oven The front panel The operation of the oven is intuitive and simple The front panel contains all user controls Figure 9 Figure 8 The 3 pronged plug power re...

Page 14: ...t yet been achieved When started cold this indicator will remain illuminated while the oven is warming up typically about 30 minutes Error the red indicator illuminates if a functional error has been...

Page 15: ...followed by the actual temperature and rotation status The rotisserie may start to turn 5 Locate the rpm display and UP DOWN keys Figure 11 Press the UP and DOWN keys to change the desired rotisserie...

Page 16: ...ng PAUSE will cause the rotisserie to slowly rotate Use this jog feature to rotate the rotisserie to new positions NOTE There is no on off button for the rotisserie You can stop the rotisserie by open...

Page 17: ...ing the oven 1 6 Slide in a cartridge carrier Only one direction is possible Figure 14 7 Clip the carriage retainer over the crossbars and the carrier Figure 15 Figure 13 Installing the carrier retain...

Page 18: ...xample place carriers at opposing 180 positions that is 3 o clock and 9 o clock on one side of the rotisserie If additional carriers are loaded do the same on the other side Up to 8 carriers may be lo...

Page 19: ...otisserie motor pause button to jog the rotisserie so that a carrier faces the front of the unit The temperature warning light turns on This can be ignored Pull on the ring of the retainer clip to rel...

Page 20: ...an 32 characters Each query string starts with a ASCII hex 2E character followed by a three character query ending with a carriage return ASCII hex 0D Each reply will end with a single byte checksum i...

Page 21: ...k and 9 o clock on the rotisserie If the problem persists contact Thermo Fisher Scientific Technical Support E22 Communications error This error will only occur in case of a syntax error in a serial p...

Page 22: ...as a dish washing detergent and warm water when necessary Do not scrub any surface with steel wool or abrasive cleansers Where there is a heavy coating of residue on the stainless surfaces or where th...

Page 23: ...tenance 1 3 Using a screwdriver and fingers gently pry out and slide the fuse holder out of the module Figure 19 4 Replace the defective fuses 5 Slide the fuse holder back into the module until it sna...

Page 24: ...0 to 240VAC 2 5A max with selector switch set to 230 50 to 60Hz Input voltage selector switch is located on the rear panel Environmental requirements Operating Temperature Range 15 C to 30 C Relative...

Page 25: ...0 1 CAN CSA C22 2 No 61010 1 04 Canada UL 61010 1 USA Low Voltage Directive 2014 35 EU EN 61010 1 General requirements Electromagnetic Conformity for Industrial Scientific and Medical ISM equipment Gr...

Page 26: ...ent Applied Biosystems GeneChip Hybridization Oven 645 Component part categories Lead Pb Mercury Hg Cadmium Cd Hexavalent Chromium Cr 6 Polybrominated Biphenyls PBBs Polybrominated Diphenyl Ethers PBD...

Page 27: ...GeneChip Hybridization Oven 645 User Guide 27 Chapter 1 The Hybridization Oven 645 China RoHS Restriction of Hazardous Substances compliance 1 China RoHS Restriction of Hazardous Substances compliance...

Page 28: ...s and protocols Certificates of Analysis Safety Data Sheets SDSs also known as MSDSs Note For SDSs for reagents and chemicals from other manufacturers contact the manufacturer Limited product warranty...

Page 29: ...For support visit thermofisher com support or email techsupport lifetech com thermofisher com 6 October 2020...

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