8
* The polymerase chain reaction (PCR) process is covered by patents issued to Hoffman
La Roche.
1. If the display does not light:
a. Make certain that the power cord is properly plugged into the wall
outlet and the back of the unit.
b. Check the fuse inside the line-filter housing. The fuse can be accessed
from the back of the unit. If blown, unplug the unit and replace with a 2A
F fuse in the XL-1000 models and a 5A F fuse in the XL-1500 model.
See ELECTRICAL SPECIFICATIONS.
2. If the display does not count after ‘‘START’’ is pressed:
Mode (ENERGY, TIME or INTENSITY) and/or value have not been
selected. OPTIMAL CROSSLINK, however,
automatically
selects the
ENERGY mode.
3. If the countdown is slower than normal:
a. Be sure that the UV sensor is not blocked during operation.
b. Look through the window in the chamber door during unit operation to
TROUBLESHOOTING
Immediately clean all spilled materials from the Spectrolinker and wipe dry. If
necessary, moisten a cloth with soap and water and clean the unit. Do not use
any harsh chemical cleaners. Do not attempt to clean the unit while it is
plugged into a power source.
CLEANING PROCEDURE
TESTING AND SCREENING RecA
The Spectrolinker can be used for testing and screening RecA mutation which
can prevent repair of UV-induced damage on cells, thereby retarding their
growth [6].
UV STERILIZATION
When the Spectrolinker is equipped with short wave (254nm) tubes, various
sterilization processes can be undertaken for laboratory purposes [7,8,9].
ELIMINATING PCR* CONTAMINANTS
The Spectrolinker can be used to eliminate contaminants that may occur
during PCR tests [10,11,12].
MISCELLANEOUS USES
The Spectrolinker can also be used whenever a metered UV dosage is
required. Either short wave (254nm), medium wave (312nm), or long wave
(365nm) UV tubes may be used for such applications. In the INTENSITY
mode, the unit may also be used to monitor intensity inside the chamber. In
this mode, however, the lamps remain on until either the ‘‘RESET’’ button is
pressed or the power is turned off.
