24
RotaChrom rCPC Operation Manual
All Rights Reserved by RotaChrom Technology LLC
©
After removing the nuts, the PEEK plugs can be removed with a 14mm pipe wrench. Do not use
standard wrench, and make sure pipe wrench covers all of the plug to prolong plug lifetime. To remove
the filling use a clean plastic or metal rod to push it out. Alternatively, forceps can be used to pull filling
out.
Stainless steel mesh can be cleaned in solvent in an ultrasonic bath. However, if it is found to contain
risk, it is possible to exchange them easily. The empty cell can be cleaned with a standard test-tube
brush.
Validation of cleaning usually utilizes the swab-probing method, where a swab soaked in a solvent
(good solvent of materiel under study) is rubbed on to the surface of the item under validation. The
swab is then put to solvent to make a reference solution which is then measured by a sufficient
analytical technique for remaining of material under study.
When cell disassembly is carried out only for swab probing, we recommend choosing a few number of
cells on a random basis. Then it is only necessary to remove front nut and tubing, then remove only
one plug per cell. Using a forceps filling can be pulled out, and cell can be swab-probed for remaining.
Cell assembly after cleaning
During the assembly of the cell (1) be sure to wear gloves. Assembly of the cells is described on 29.
figure, as cells should be filled in with the filling material (5). Using a cigar-making movement roll the
filler into the tube then push on both ends with fingers or a plastic rod. Cover the NPT thread of the
plugs (2) with 3-4 layer of standard PTFE tape (A-A-
58092 standard, „white” or „yellow” coded). Screw
on the two plugs with a 14 mm pipe wrench and fix with a torque of 11 Nm. Do not use standard
wrench and make sure pipe wrench firmly covers all of the plug.
