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TangenX
TM
SIUS
TM
PD Filter Plate & 2-Bolt Clamp Assembly
User Guide
Identification
IF.PUG.019
Revision
R2
Approved
20-DEC-2018
2.
Product Contents
•
TSLDI-2BMC package includes the following:
o
Stainless steel clamp as shown in Figure 1.1 (Items 1-9)
o
Certificate of Conformance
•
TFPLS-SA08 or TFPLS-LVFL package includes the following:
o
Filter Plate Insert
o
Isolation Plate
o
Certificate of Conformance
•
Cassette package includes the following:
o
TangenX™ SIUS™ PD membrane filtration cassette available with
0.01 m², 0.02 m², or 0.1 m² area
LP screen, J or K open channel
o
EPDM gaskets
•
Certificate of Conformance
3.
Important information before you begin
•
HOLDER / CLAMP
-
TSLDI-2BMC is shipped assembled; remove the plastic shipping plate from between stainless
plates before use.
-
The clamp may be cleaned with alcohol or any other detergent solution commonly used to
clean tables and lab equipment.
-
TSLDI-2BMC weighs approximately 13 lbs, use caution when lifting.
•
FILTER PLATE INSERT
-
Filter Plate Insert kits are shipped cleaned, dry and ready for use.
-
TFPLS-SA08 and TFPLS-LVFL is compatible with all TangenX™ SIUS™ single-use cassettes and
TangenX™ PRO reusable cassettes.
-
Filter Plate Inserts are designed for single-use. Since Repligen does not recommend re-use, it
is the responsibility of the end user to define a suitable cleaning protocol.
•
CASSETTE
-
Product is packaged wet and must remain hydrated for optimal performance. Keep bag
sealed until cassette installation (Section 6, Step 3 below).
-
TangenX™ SIUS™ PD cassettes are compatible with all TangenX™ cassette holders.
-
Cassettes may be stacked to increase filtration surface area; however, use only one type of
membrane molecular weight cutoff at one time.
DO NOT install a mixture of cassettes with
different pore sizes in the hardware - one pore size only per cassette stack installation.
-
Cassettes must be equilibrated with an appropriate buffer (i.e. phosphate buffered saline) to
ensure the neutralization of the 0.2M sodium hydroxide storage agent in the membrane
filter. It is important to use pre-filtered buffer to avoid fouling the membrane or introducing
contaminants into the system that could affect membrane performance and product
recovery.
•
GASKET
-
Gaskets are intended to be single use; Repligen recommends that you replace gaskets with
each cassette changeover. Repligen supplies two gaskets per cassette. Installation of the
first cassette requires two gaskets; stacking additional cassettes requires only one gasket.
Extra gaskets should be saved to replace worn or damaged gaskets.
