Quattroflow Installation, Operation & Troubleshooting Guide
Rev. 0
Page 5 of 25
www.quattroflow.com
2
BASICS
2.1
General description of Quattroflow Pumps & Functioning
Quattroflow™ develops and manufactures single-use and multiple-use Quaternary (Four-Piston) Diaphragm
Pumps for critical applications in the biopharmaceutical industry. This technology is CIP/SIP capable and
offers disposable solutions that increase flexibility, reduce down-time, eliminate costs of cleaning validation,
and risks of cross-contamination. Quattroflow pumps can be found in all areas of biologic manufacturing such
as cross-flow filtration systems, chromatography, and centrifuges. Quattroflow ensures safety, efficiency and
reliability for handling biologics such as plasma products, therapeutic proteins, monoclonal antibodies,
vaccines, and other high value products.
Technical definition:
Reciprocating positive displacement pumps
Diaphragm pump (membrane pump)
The Quattroflow displacement pump is based on this principle. The 4-piston (quaternary) diaphragm
technology enables a gentle pumping. Each stroke of the four diaphragms is generated by an eccentric shaft,
which is connected to the electric motor.
The four segments of the pump diaphragm oscillate back and forth. This alternate movement is created by a
connector plate (nutating disc) that is arranged on a ball bearing. The ball bearing sits on an eccentric shaft.
The connector plate does not turn.
The inlet and outlet check valves restrict fluid motion to the desired direction from the inlet connection port
to the outlet connection port.
Figure 1 Sectional drawing of the Quattroflow pump head
Figure 2 Sectional drawing of the Quattroflow pump head
