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QF4400SU; edition 2018-11; page 4 of 19  

 

2. Description of the QF4400SU pump 

 

2.1. Appropriate use 

 
The Quattroflow  4400SU is a 4-piston Diaphragm pump, which is mainly used to pump water-like fluids 
that are typically handled in research-, pilot plant- or production facilities of the pharmaceutical, biotech, 
food or cosmetic research centers or plants.  
Examples: 

 

Solutions containing proteins (albumin, IgG, Clotting factors, monoclonal antibodies, enzymes, 
vaccines.) 

 

Solutions of polymers or suspensions (silicon, latex, chromatography media) 

 

Cell suspensions  (bacteria, yeast, algae, fungi, mammalian cells) 

 

Colloidal solutions 

 

Suspensions of viruses or phage 

 

Dairy products 

 

Gelatine 

 

Supplements and ingredients for cosmetic and food 

 

 
Typical applications for the QF4400SU 

 
- Filtration technology: 

 

To  recirculate  feed/retentate  (e.g.  membrane  cassettes,  hollow  fibre,  spiral  wound,  ceramic 
elements)  

 

Feed pump for filter cartridges or plate and frame depth filters 

 
- Chromatography: 

 

Packing of chromatography columns 

 

Feed pump to mix gradients 

 
- Feed pump for centrifuges or separators 
 
- Feed pump for homogenizers 
 
- Feed pump for filling machines 
 
 

2.2. General description of the machine  

 
The  Quattroflow  4400SU  pump  is  a  4-piston  diaphragm  pump.  The  four  segments  of  the  pump 
diaphragm  oscillate  back  and  forth.  This  alternate  movement  is  created  by  a  connector  plate  that  is 
arranged on a ball bearing. The ball bearing sits on an eccentric shaft. The connector plate does not 
turn! 
 
The stroke of the pistons is determined by the angle of the eccenter. There are eccentric shafts with 6° 
available.  
 
Range of flow rate: 150-5000 L/h (40-1321 gph). For the compact model QF 4400 HT with integrated 
controller please see chapter 2.4. 
 

Please note: 

The orientation of in- and outlets can be adjusted by turning the pump chamber in 90° steps.  
 
The Quattroflow 4400SU is self-priming and can run dry. Inside the pump chamber there are no rotating 
parts that might cause heating up of the product or shed particles.  
 

Summary of Contents for 4400SU Series

Page 1: ...e left hand and with separate control box no image or with integrated controller HT model image right hand other versions are possible Please read this manual carefully before start up of the pump and...

Page 2: ...with the safety instructions 8 3 5 Safety hints for the operator 8 3 6 Safety instructions for maintenance inspection and mounting operations 9 3 7 Unauthorized reconstruction and spare part usage 9 3...

Page 3: ...echanical influences The following storage conditions are recommended Steady ventilated dust and vibration free storage room Ambient temperature between 15 C 59 F and 25 C 77 F with a relative humidit...

Page 4: ...p for filter cartridges or plate and frame depth filters Chromatography Packing of chromatography columns Feed pump to mix gradients Feed pump for centrifuges or separators Feed pump for homogenizers...

Page 5: ...h appropriate analytical methods the success of the flushing procedure Recommendation Test run prior first use Before using your pump in your process perform a test run to get used to the specific pro...

Page 6: ...internal supply voltage too low err4 internal supply voltage too high Attention The optimal motor parameter are set by the factory Only authorized and qualified personnel should change the parameter o...

Page 7: ...p chamber in a vacuum autoclave at max 130 C 266 F for max 30 min Follow instructions of the autoclave manufacturer 4 After cooling down the screws of the membrane housing cover and the connectors sho...

Page 8: ...ease follow strictly the safety guidelines of this manual as well as all national and possible internal regulations e g the handling of chemicals like caustic or acid the handling of biological materi...

Page 9: ...tart up and check the tightness of the pump o Please respect the relevant additional security advices if the pump has been used for aggressive dangerous or toxic liquids e g suitable protective equipm...

Page 10: ...tool for the specific application The user operator is responsible to perform a proper method of testing if the pump should be applied for his specific application The chemical and thermal compatibili...

Page 11: ...led personnel Check the electrical cables before connecting to mains supply During all maintenance work it has to be ensured that no explosive atmosphere can arise Appropriate protection equipment is...

Page 12: ...haft should be verified For corrosion reasons or a clearly audible operating noise the parts of the bearing service kit should be also replaced PSKITWLC44 Please follow the general guidelines and safe...

Page 13: ...dation is inapplicable The replacement of the pump chamber can be conducted by the operator Please follow the drawings for the disassembly and assembly Before starting the disassembly ensure that the...

Page 14: ...sider the following tightening torques during the installation of the pump chamber Picture 1 Step 3 Fastening screws 25 Nm 18 4 lb ft Picture 3 Step 1 Clamp ring screw 5 Nm 3 7 lb ft 1 Pull SU pump ch...

Page 15: ...e operator The following drawings describe it step by step 3 Mounting in reverse order with the new shaft bearing unit Pay attention that between both coupling halves has to be a gap of 2 3 mm 4 For m...

Page 16: ...d open valve in discharge line completely remove obstruction in discharge line 9 X Pressure line completely or partly clogged diaphragm maybe broken change diaphragm 10 X The diameter of the pipes in...

Page 17: ...rpm x reduction ratio Depending on the selected motor frequency drive combination the motor frequency and the resulting pump speed might differ 6 2 Performance charts of the QF4400SU HT The flow rates...

Page 18: ...eed range pump rpm 20 1200 10 1200 Connection specification inlet standard Connector 1 5 TC 1 5 TC Flange diameter mm inch 50 5 1 99 50 5 1 99 Internal diameter mm inch 34 8 1 37 34 8 1 37 Connection...

Page 19: ...d Motor QF4400SU HT Integrated controller Motor Gear Manufacturer standard Siemens SEW Type 1LE1003 CMP80M Rated speed min 1 1435 50 Hz 1200 Voltage V 230 400 400 Ampacity A 7 7 4 4 13 4 Power KW 2 2...

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