6.2 Aerosol data according to ISO 27427
The aerosol characteristics presented in these instructions for
use were determined in accordance with ISO 27427 using Sal-
butamol. If other solutions or suspensions are used for
nebulisation, the aerosol characteristics may differ from the val-
ues shown (particularly if they have greater viscosity).
The following data is based on tests according to a standard
which takes adult breathing patterns as a basis. Therefore,
these figures will probably differ from corresponding figures
that were calculated for populations of children and infants.
Nozzle insert (red)
Minimum com-
pressor flow
(3 l/min –
0.6 bar)
Nominal com-
pressor flow
(4 l/min –
1.2 bar)
6
Maximum com-
pressor flow
(6 l/min –
1.9 bar)
MMAD [µm]
7
3.3
2.7
2.0
GSD
8
2.03
2.17
2.23
Respirable fraction
[% < 5 µm]
71.8
79.2
86.3
Aerosol fraction
[% < 2 µm]
23.6
35.0
49.4
Aerosol fraction
[% > 2 µm < 5 µm]
48.2
44.2
36.9
Aerosol fraction
[% > 5 µm]
28.2
20.8
13.7
Aerosol output [ml] 0.44
0.49
0.34
Aerosol output rate
[ml/min]
0.05
0.07
0.08
Residual volume
[ml] (gravimetric)
0.99
0.94
0.99
6) Operation with PARI COMPACT2 compressor (Type 152).
7) MMAD = Mass Median Aerodynamic Diameter
8) GSD = Geometric Standard Deviation
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