NeurOptics® PLR®-3000 Pupillometer System—Instructions for Use © 2018 NeurOptics, Inc.
4
Set Measurement Protocol
From the main screen (Ex. 12), select the
Settings
icon
and then the top right icon (
Define Protocol
, Ex. 15) to
navigate to the
Change Protocol Parameters
menu (Ex. 16).
Each parameter listed in the two pages of this menu (Ex. 16)
can be changed by toggling the values reported using the
left “<” and right “>” keys in the directional keyboard.
Five different experimental protocols can be saved in
memory and retrieved later when a specific protocol is needed. Press
Select
to active a protocol. Use the
left “<” and right “>” keys in the directional keyboard to change the protocol number. Use the list of parameters
below to change the settings of the selected protocol.
Use this setting to change the type of the experiment:
Positive Pulse Stimulus:
standard pupil light reflex, a bright pulse over a dimmer background triggers a pupil constriction.
Negative Pulse Stimulus:
dim pulse over a brighter background triggers a dark reflex and pupil dilation.
Static Stimulus:
no light stimulation and no pupil reflex, just a continuous and static light background.
Extended Mode:
pupil is recorded at a lower frequency for an extended period of time (maximum duration 10 minutes).
Pulse Intensity.
Use this setting to change the intensity of the light stimulus. Unit of light is radiometric and provided
in micro Watts, uW. Five different intensities are provided: 0uW, 1uW, 10uW, 50uW, 121uW, and 180uW.
Background Intensity.
Use this setting to change the background light intensity. Note that in case of a Positive Pulse
Stimulus protocol, Background Intensity must be less than Pulse Intensity whereas, for a Negative Pulse Stimulus,
protocol it is the opposite -- Background must be higher than the Pulse Intensity.
Measurement Duration.
This setting is for setting the duration of the measurement, a minimum of 3 seconds up
to a maximum of 41 seconds.
Pulse Duration.
This is the duration of the light pulse stimulation, a minimum of 0.03 sec for the Positive Pulse
and 1 sec for the Negative Pulse.
Pulse Onset.
This is the start of the Pulse stimulation.
In case there is a conflict in the settings, for example the Background Intensity is set brighter than the Pulse Intensity
in a Positive Pulse Stimulus protocol, then the corresponding icons are shown in red and the Define Protocol menu
cannot be exited until the conflict is resolved.
Measure Pupils
The PLR-3000 should not be used without the eye cup positioned correctly (Ex. 17). It is
very important that the eye cup be correctly fitted. A snug fit helps reduce the possibility
of stray light entering the eye while the scans are taking place. The eye cup has a tab in
the rim, which fits into the indentation in the lens shield of the Pupillometer. Position the
tab in the eye cup rim into the indent in the lens shield and press into place. The tabs on
either side of the lens shield should also snap into the holes on either side of the eye cup.
Position the PLR-3000 with the eye cup at a right angle
to the patient’s axis of vision, minimizing any tilting of the
device (Ex. 18).
Ex. 18
Ex. 17
Ex. 15
Ex. 16