107
Manual URYXXON
®
Relax EN, V 6.03 / 08.22
Diagnostic specificity, diagnostic sensitivity, negative predictive value and positive predictive
value for parameters blood, urobilinogen, bilirubin, protein, nitrite, ketones, ascorbic acid,
glucose and leukocytes are summarized in the following table. Overall, diagnostic specificity
is 97 % and diagnostic sensitivity is 98 %. The average negative predictive value is 98 %; the
average positive predictive value is 91 %. Values for the parameters pH and density cannot be
calculated because these parameters do not allow negative/positive interpretation.
Parameter
Diagnostic
specificity
Diagnostic
sensitivity
NPV
PPV
Blood
100 %
89 %
84 %
100 %
Urobilinogen
95 %
100 %
100 %
71 %
Bilirubin
95 %
100 %
100 %
86 %
Protein
97 %
97 %
98 %
96 %
Nitrite
96 %
98 %
99 %
86 %
Ketones
100 %
98 %
100 %
100 %
Ascorbic acid
100 %
100 %
100 %
100 %
Glucose
100 %
97 %
99 %
100 %
pH
N/A
N/A
N/A
N/A
Density
N/A
N/A
N/A
N/A
Leukocytes
88 %
100 %
100 %
76 %
overall average
97 %
98 %
98 %
91 %
Likelihood ratios for parameters URO, BIL, PRO, NIT, KET, ASC and GLU were calculated
as LR+ > 10 and LR- < 0.1, which demonstrates convincing diagnostic evidence. For the
parameter LEU, likelihood ratio was calculated as LR+ 5 – 10, which demonstrates high
diagnostic evidence. LR- was < 0.1 for this parameter. For the parameter BLD, likelihood ratios
were calculates as LR- 0.1 – 0.2, which demonstrates high diagnostic evidence. LR+ was > 10
for this parameter. Calculation of LR+ and LR- is not possible for pH and SG as diagnostic
sensitivity and diagnostic specificity are not applicable for these parameters.