1.
Introduction
The 7000smz and 5000mz Tissue Slicers by Campden Instruments are oscillating
blade microtomes and are the result of more than 25 years experience in the design
and manufacture of tissue slicers.
The 7000smz is a programmable unit that allows the instrument to ‘learn’ a cutting
cycle input by the operator and then repeat that cycle a desired number of times. The
cycle may have a varying speed/distance profile so that particular areas of tissue can
be sliced at different speeds.
The 5000mz is similar in most respects to the 7000smz except that it is not
programmable and does not have the superior accuracy specification.
A number of researchers have found that certain combinations of oscillation
frequency; oscillation amplitude and tissue advance rate can give superior slice
quality for a given tissue. The 7000smz and 5000mz allow these combinations to be
developed solely by input from the keypad.
For machine stability and long life the amplitude of cut is related to the frequency of
oscillation – the larger the amplitude, the lower the maximum frequency available and
vice versa.
Experienced users of oscillating microtomes will no doubt be aware that large
amplitudes and/or high oscillation frequencies can lead to excessive vibration and
unstable tissue fluid. The 7000smz and 5000mz instruments benefit in this area by
being built on a heavy, rigid cast base giving exceptional immunity to secondary
vibration transmission.
The purpose of this manual is to allow the user to achieve expertise in the use of the
7000smz and 5000mz instruments. Please read and understand the information
contained in this manual before using the instrument. Only competent and capable
personnel should use the instrument.
This document should be retained for future reference as it contains the name and
address of the manufacturer within the EC.
PACKAGING
Please retain the original packaging for future use.
Instruments will not be accepted for service or repair
unless the unit has been
adequately and properly packaged. Additionally instruments will not be accepted
without prior authorisation and have been certified as being uncontaminated with any
material that may be hazardous to the health of service personnel. A Returns
Authorisation and Decontamination Certificate blank form is included in Section 9 of
this manual and may be photocopied as required. Blank forms can also be obtained
by contacting Campden Instruments.
Campden Instruments Limited
PO Box 4148
Loughborough
Leicestershire
LE12 7XT
UK
Telephone: (+44)
0150
9814790
Fax:
(+44)
0150
9817701
E-Mail:
www.campdeninstruments.com