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PROMETRA® II PROGRAMMABLE PUMP
Page 29 of 38
Caution: Do not force the needle. Excessive force on the needle may damage the needle
tip. Do not rock the needle sideways as this could damage the septum or cause drug to
leak from the reservoir.
3.
Inject the 5 mL of sterile preservative-free 0.9% saline solution into the drug reservoir. Allow
the saline solution to return from the pump reservoir into the empty syringe barrel. (ensure
that all air is removed, if a plunger is present it may prevent all air from being expelled)
Note: Return volume may be more or less than the infused volume. If air is noted, repeat
the priming procedure with another 5 mL of the sterile preservative-free 0.9% saline
solution.
4.
Remove the syringe from the needle.
Note: Since some sterile saline will remain in the pump reservoir, the final concentration of
drug varies based on the fill method. See the below table for the expected reduction in
concentration.
Expected concentration of drug in pump reservoir based on fill
method
Filling without
rinsing
Rinsing with 20 mL of
drug
86%
97%
5.
If rinsing the pump before filling, rinse and discard the returned volume based on the fill
method shown above.
6.
Verify that the volume of infusate in the syringe does not exceed 20 mL, the maximum volume
of the pump reservoir. Attach the syringe filled with the infusate to the 22G non-coring needle
provided with the pump.
Caution: When first filled, the Prometra II Pump has a small amount (2-3ml) of sterile
water in the pump. As a result, there is an approximate 13% dilution of drug in the initial
filling of the 20mL drug reservoir.
7.
Inject the infusate into the pump reservoir. Remove the needle and syringe assembly from the
refill septum.
8.
Remove and discard the knotted silicone rubber tubing from the pump stem.
9.
Attach a syringe filled with 5 mL of sterile preservative free 0.9% saline to the 20G Catheter
Access Port needle. Advance needle through the Catheter Access septum until needle tip
resides completely inside the Catheter Access chamber.