Cardinal Health Alaris PK, Directions For Use Manual, Page: 40 / 46

1000DF00005 Iss. 2
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Diprivan 1% Marsh Model BD 50ml Syringe Diprivan 2% Marsh Model BD 50ml Syringe
Profiles from TCI mode - Predicted vs Ideal Concentration
Sufentanil Gepts Model BD 50ml Syringe
Remifentanil Minto Model BD 5ml Syringe Remifentanil Minto Model BD 50ml Syringe
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
0 5 10 15 20 25 30 35 40 45 50 55 60
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
Patient Age: 40 Yrs
Patient Weight: 60kg
Drug Concentration: 10mg/ml
Plasma Concentration Accuracy: +0.2%
Time Interval (mins)
P
re
d
ic
te
d P
la
sm
a
C
o
n
ce
n
tr
at
io
n (n
g
/m
l)
Id
ea
l P
la
sm
a
C
o
n
ce
n
tr
at
io
n (
µ
g
/m
l)
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
0 5 10 15 20 25 30 35 40 45 50 55 60
0.0
1.0
2.0
3.0
4.0
5.0
6.0
7.0
8.0
Patient Age: 40 Yrs
Patient Weight: 60kg
Drug Concentration: 20mg/ml
Plasma Concentration Accuracy: -0.3%
Time Interval (mins)
P
re
d
ic
te
d P
la
sm
a
C
o
n
ce
n
tr
at
io
n (n
g
/m
l)
Id
ea
l P
la
sm
a
C
o
n
ce
n
tr
at
io
n (
µ
g
/m
l)
0.0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
4.0
0 5 10 15 20 25 30 35 40 45 50 55 60
0.0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
4.0
Patient Age: 75 Yrs
Patient Weight: 65kg
Patient Height: 175cm
Patient Gender: Male
Drug Concentration: 50µg/ml
Plasma Concentration Accuracy: +0.2%
Time Interval (mins)
P
re
d
ic
te
d P
la
sm
a
C
o
n
ce
n
tr
at
io
n (n
g
/m
l)
Id
ea
l P
la
sm
a
C
o
n
ce
n
tr
at
io
n (n
g
/m
l)
0.0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
4.0
0 5 10 15 20 25 30 35 40 45 50 55 60
0.0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
4.0
Patient Age: 75 Yrs
Patient Weight: 65kg
Patient Height: 175cm
Patient Gender: Male
Drug Concentration: 50µg/ml
Plasma Concentration Accuracy: +0.5%
Time Interval (mins)
P
re
d
ic
te
d P
la
sm
a
C
o
n
ce
n
tr
at
io
n (n
g
/m
l)
Id
ea
l P
la
sm
a
C
o
n
ce
n
tr
at
io
n (n
g
/m
l)
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
0.40
0 5 10 15 20 25 30 35 40 45 50 55 60
0.00
0.05
0.10
0.15
0.20
0.25
0.30
0.35
0.40
Drug Concentration: 5.0µg/ml
Plasma Concentration Accuracy: +3.1%
Time Interval (mins)
P
re
d
ic
te
d P
la
sm
a
C
o
n
ce
n
tr
at
io
n (n
g
/m
l)
Id
ea
l P
la
sm
a
C
o
n
ce
n
tr
at
io
n (n
g
/m
l)