Biotage TurboVap 96 Dual User Manual Download Page 11

11

Prepare the System

Prepare the System

Replace the Manifold

Warning

 

»

The nozzles may have come into contact with hazardous 

samples. Avoid contact. 

 

»

Ensure not to bend any of the nozzles. If a nozzle is bent, it is 

recommended that the manifold is replaced.

 

»

Do not touch the inside of the gas heater. Touching may leave 

residues that can contaminate the following runs.

 

»

Always turn off the system, disconnect the power cord, and let 

the system cool down before performing maintenance.

Figure 15.

 Potential biohazard. Use appropriate PPE if the system has 

processed biohazardous samples.

There are three different manifolds available. The manifold 
is selected according to the well plate or rack to be used. 
For further information, see "Manifolds" on page 5.

1.  Remove the fume shield. Loosen the fume shield set screw, 

slide out the fume shield and remove it. See Figure 16.

Figure 16.

 Remove the fume shield.

2.  Use the Torx T20 key (P/N 411886) supplied with the system 

to remove the two screws that secure the manifold to the 
gas heater, see Figure 17. Ensure that the manifold is held in 
position while the last screw is removed. 

3.  With a steady grip, remove the manifold.

Note: 

Do not hold the manifold by the nozzles as this might bend 

the nozzles.

4.  Examine the new manifold and the gasket for debris. If there 

is debris between the manifold and the gas heater, gas 
leaks can occur.

Note: 

Do not touch the inside of the gas heater. Touching may 

leave residues that can contaminate the following runs.

5.  Use the 2 pins on the gas heater to guide the new manifold 

in position. See Figure 17.

6.  Secure the new manifold with the

 

screws. 

Note:

 Ensure that the screws are tightened by hand using the 

Torx T20 key.

7.  Install the fume shield.
8.  Finger tighten the fume shield set screw. 
9.  Clean the removed manifold and let it dry (see "Clean the 

Manifolds" on page 20). Store the replaced manifold in a 
dust free environment.

10. Check that the user interface is set to the correct manifold, 

see "Common Settings" on page 8.

Figure 17.

 Remove the 2 screws and the the manifold. 

Set the Pressure

Warning

 

»

To avoid injury to person or damage to the system, do not 

exceed the maximum inlet pressure of 6.5 bar (0.65 MPa, 

94 PSI).

To set the appropriate pressure, see TurboVap

®

 96 Dual 

Installation and Safety.

Summary of Contents for TurboVap 96 Dual

Page 1: ...Patent Pending Biotage 2021 Title Truncated if Neccessary Page 1 TurboVap 96 Dual User Manual...

Page 2: ...8 Define System Settings 8 Common Settings 9 Evaporation Settings 10 Network and Firmware 10 System Information 10 Warnings in the Software 11 Prepare the System 11 Replace the Manifold 11 Set the Pr...

Page 3: ...s manifolds with 24 48 or 96 nozzles to allow for processing of up to 96 samples in each cabinet The left and right cabinet can perform simultaneous evaporation runs with varying size well plates vary...

Page 4: ...he door is closed the evaporation run will resume To determine the correct plate height for an evaporation run see Determine Optimal Evaporation Conditions on page 6 Evaporation To provide consistency...

Page 5: ...the Manifold on page 11 according to the chosen well plate Available manifolds TurboVap manifold with 24 gas nozzles TurboVap manifold with 48 gas nozzles TurboVap manifold with 96 gas nozzles Differe...

Page 6: ...radation of analytes may be observed Do not allow samples or solvents to boil The evaporation time of samples decreases with increasing sample cleanliness The presence of sample detritus or particulat...

Page 7: ...plate Usually setting the temperature of the plate heater 0 20 C above the gas temperature allows for enhanced evaporation uniformity Use of the plate heater minimizes cross contamination of samples w...

Page 8: ...ifying and calibrating the touch screen 1 Mode Mode selection Press to select mode 2 Common Settings Press to change common settings 3 Evaporation Settings Press to change evaporation settings 4 Netwo...

Page 9: ...as temperature Tick the box to wait for the gas temperature to reach the set value before starting an evaporation Wait for plate temperature Tick the box to wait for the plate temperature to reach the...

Page 10: ...ress the Reset Settings button to reset all settings in Common settings Evaporation Settings and Network and Firmware to their default values Calibrate Touch Press the Calibrate Touch button to calibr...

Page 11: ...ure 17 Ensure that the manifold is held in position while the last screw is removed 3 With a steady grip remove the manifold Note Do not hold the manifold by the nozzles as this might bend the nozzles...

Page 12: ...Time Mode Evaporate for a set period of time 4 Method Mode Evaporate using a predefined method 5 Split to left and right OR Join left and right The left and right cabinets operate independently OR The...

Page 13: ...splay shows that the left side is ready to start the orange Start button is active and the right side is running an evaporation the blue Pause button and the red Stop button are active To perform a Ti...

Page 14: ...ode In the Join left and right mode the left and right cabinets operate the same evaporation run with the same parameters see Figure 23 Figure 23 Temp Step Method 96 run in Join left and right mode Du...

Page 15: ...utton to enter the desired name see Evaporation Parameters on page 15 6 When done press Save Note Once a method has been saved its previous settings cannot be recovered 7 In the Methods view press OK...

Page 16: ...ers view where the evaporation parameters or the method name can be edited or a method can be copied Figure 29 Press and hold the Plate height button then move the lift by pressing the Up and Down arr...

Page 17: ...an alarm sounds If operating each cabinet separately then the LED lights in each cabinet will turn green independently The Evaporation Finished dialog appears on the screen see Figure 34 The alarm co...

Page 18: ...l risk for burn damage Open the cabinet door The well plate will descend Carefully remove the well plate or rack Be careful not to come in contact with the nozzles See Figure 35 Note The lift will ret...

Page 19: ...ly dampened with isopropanol or ethanol 3 When the system has been cleaned connect the power cord and turn on the system Clean the Interior of the System Warning Never clean the surface where the mani...

Page 20: ...following is recommended a For polar analytes chose solvent combinations with a high aqueous content e g an 80 20 solution of water and methanol b For lipophilic analytes chose solvent combinations wi...

Page 21: ...plied by Biotage Incorrect fuses will void the warranty of the system and creates a potential fire hazard and a risk of personal injury 1 Turn off the system and disconnect the power cord 2 Using a fl...

Page 22: ...into Storage Warning Ensure not to bend any of the nozzles If a nozzle is bent it is recommended that the manifold is replaced 1 Remove and clean the manifolds as described on page 20 2 Place the man...

Page 23: ...er Temperature on page 7 Check that the sample is not left too long on the plate heater after the evaporation is completed Check that the gas flow is not too high and causing splashing see Determine t...

Page 24: ...crew 1 Consumables Part No Description Qty 121 5201 Collection Plate 350 uL Square 50 121 5202 Collection Plate 1 mL Square 50 121 5203 Collection Plate 2 mL Square 50 121 5213 Collection Plate 2 mL R...

Page 25: ...25 Notes Notes...

Page 26: ...art Number 418001 B 2021 Biotage All rights reserved No material may be reproduced or published without the written permission of Biotage Information in this document is subject to change without noti...

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