www.bedfont.com
6
NOxBOX
®
mobile Operating Manual
English
General Description
The NOxBOXmobile is used to control the
pressure and flow of NO gas into a patient
breathing circuit. The flow of NO gas is
controlled by the user via the adjustable
flow meter (See Fig.1, item G). When used
in conjunction with a NOxBOXO
2
monitor, a
complete delivery and monitoring system is
formed that allows the user to set the patient
dose level and continuously monitor the dose
gas at patient side.
The NOxBOXmobile system is mounted to an
epoxy coated, mild steel trolley designed to be
situated close to the patient’s bedside ventilator.
The NOxBOXmobile system provides capacity
for two NO supply cylinders, up to 20L water
capacity, which when combined with the auto-
changeover system ensures uninterrupted
delivery of NO is possible. When used correctly,
this helps guard against sudden unexpected
withdrawal from INO therapy.
The system is fitted with stainless steel high-
pressure hoses that attach to the cylinders
via suitable cylinder connectors (specific to
individual region). These hoses are fitted with
a safety-cord to restrain the hose in the event
of a catastrophic pressure burst. Further safety
control measures are provided by a pressure
relief valve fitted after the first stage regulator,
with a second pressure relief valve fitted after
the second stage regulator.
INO Therapy Monitor
The system trolley is provided with a shelf that
allows a NOxBOXO
2
monitor to be fixed to the
system, providing the monitoring capability.
Refer to the NOxBOXO
2
manuals for safe use
and maintenance.
Environmental Alarms
Optional NOxAIR environmental gas detectors
can be provided to warn personnel of any
leaks in the NO supply. These portable alarms
continuously monitor the atmosphere for NO
or NO
2
levels (depending on model), capable
of measuring down to 0.1ppm. Each monitor
has a set of alarms that can be set to ensure
best-practice environmental monitoring. These
alarms can be worn by an individual, positioned
in the vicinity of the patient or left on the hooks
provided on the NOxBOXmobile. Refer to the
NOxAIR environmental gas detector manuals
for safe use and maintenance.
Note: The NOxAIR alarms are personal alarms,
designed to alert staff in the immediate vicinity
of the alarm. They are not designed to be heard
from a long distance or from a different room.
NO Gas Cylinders
The NOxBOXmobile system is designed for
use with a medical-grade gas mixture of NO
balanced in Nitrogen (N
2
). The maximum
recommended concentration for use is
1000ppm NO. Bedfont Scientific do not provide
therapeutic gas mixtures for INO therapy.
Refer to the manufacturer’s labels regarding the
concentration and precise mixture of the NO/
N
2
gas.
Please refer to the manufacturer’s instructions
on safe handling of the gas, gas cylinder and
any additional gas handling equipment provided.
All safety notices and warning should be read
and understood prior to use.
Warning: N
2
gas is an asphyxiant, and care
should be taken to understand that adding
large quantities of N
2
to the patient circuit may
cause dilution of the oxygen content of the
patient gases. It is recommended at all times
during INO therapy to use a monitor such as the
NOxBOXO
2
that provides oxygen monitoring
capability to maintain awareness of this
phenomenon possibly occurring.