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1 Description

1.4

Design

The Pharma-line S is in hygienic design in line with ASME BPE, USP and cGMP requirements.

The Pharma-line S has no dead-legs and is fully drainable on the product side. All product wetted parts in the Pharma-line S are
mechanically polished to Ra <0.5 µm or electropolished to Ra >0.4 µm.

The tubes are seamless and polished prior to bending. The Pharma-line S U-tubes are bent to a larger radius than required in
ASME BPE. The Pharma-line S is easy to clean and can be steam sterilised. The gaskets are FDA approved and USP class VI.

Main components

5300-0005

A

C

D      

D

F

E

G

G

J

K

B

H

A
B
C
D
E
F
G
H
J

NAC plate connection
Fronthead
Tubesheet
Lifting lug
Vent
Flange connection
Leg
Shell
Flange connection

Tube sheet

Tubes are expanded into first sheet, welded and expanded into second sheet. Double tube
sheet minimises the risk of contamination

Shell

Utility media flow on the shell side

Tube bundle

Product flows through a number of tubes which are bundled together

Vent

Vent connection on shell side for venting of air

Drain

Drain connection on shell side for draining

NAC plate connection on
product side

Tri-clamp ferrule to be connected to the heat exchanger by an NAC plate. Tri-clamp ferrules
and gaskets are not supplied

Flange connection on shell side Inlet flange is at the back of the heat exchanger. Outlet flange is placed at the side of the shell
Lifting lug
Legs

To be used when lifting the unit, fixed with bolts and movable, allowing for flexible positioning.

6

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Summary of Contents for Pharma-line S 1

Page 1: ...5300 0001 ESE02599 EN3 2016 07 Original manual Instruction Manual Alfa Laval Pharma line S www sks online com www sks webshop com...

Page 2: ...www sks online com www sks webshop com...

Page 3: ...2 5 Cleanliness provisions 9 2 6 Connecting the heat exchanger to the piping system 9 2 7 Fitting and piping 10 3 Operation 11 3 1 Design and operating conditions 11 3 2 Operating procedures 11 3 2 1...

Page 4: ...in this manual 1 2 Recycling information Packing Packing materials consist of wood plastics and metal Wood can be reused recycled or used for energy recovery Plastics should be recycled or burnt at a...

Page 5: ...nology industries The Pharma line S is used in pharmaceutical water systems Water For Injection WFI Purified Water PW and for heating or cooling of pharmaceutical products It is available in a number...

Page 6: ...g lug Vent Flange connection Leg Shell Flange connection Tube sheet Tubes are expanded into first sheet welded and expanded into second sheet Double tube sheet minimises the risk of contamination Shel...

Page 7: ...For Pharma line S s in category I and II EC type examination and product verification from Zetterstr ms Rostfria AB Zetterstr ms Rostfria AB is certified to issue EC type examination and product veri...

Page 8: ...racies 2 3 Positioning and slope The legs can be fixed in 4 different positions 0 90 180 and 270 which allows for a flexible installation depending on where the unit is to be installed Once the positi...

Page 9: ...otective plugs should not be removed until just prior to installation Dirt removal The entire system should be clean before starting operation 2 6 Connecting the heat exchanger to the piping system Co...

Page 10: ...ger The shell side is equipped with the option to vent and drain Vent and drain valves should be provided so the unit can be purged to prevent air vapour or gas binding Before use of the vent and or d...

Page 11: ...rt up operation During start up all vent valves should be opened and left open until all passages have been purged of air and are completely filled with fluid At start up or after the unit not been in...

Page 12: ...educe water retention after drainage the tube side of the heat exchanger should be blown out with air Temperature shocks The heat exchanger should not be subjected to sudden temperature fluctuations H...

Page 13: ...e heat exchanger has double tube sheets and a leakage in the joint in the inner tube sheet will show as a leakage between the double tube sheets A leakage in the joint in the outer tube plate will als...

Page 14: ...ange A B C Pharma line S 1 mm Pharma line S 1 0 1 76 1 DN50 1150 225 195 Pharma line S 1 0 3 89 1 DN50 1150 225 195 Pharma line S 1 0 4 101 1 DN50 1150 225 195 Pharma line S 1 0 6 104 1 1 2 DN50 1150...

Page 15: ...ension T1 Tube inlet NAC plate for Tri clamp Suitable for ASME BPE T2 Tube outlet NAC plate for Tri clamp Suitable for ASME BPE M1 Shell inlet Weld neck flange DIN2635 EN1092 1 M2 Shell outlet Weld ne...

Page 16: ...nt gaskets should be purchased in the material originally provided with your heat exchanger When ordering replacement gaskets or plate flange please refer to the item No in the spare part list for Pha...

Page 17: ...should be purchased in the material originally provided with your heat exchanger When ordering replacement gaskets or plate flange please refer to the item No in the spare part list for Pharma line S...

Page 18: ...of the user of this document to comply with all applicable intellectual property laws Without limiting any rights related to this document no part of this document may be copied reproduced or transmi...

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