PG13
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voltage. This is only true if you do not modify the kit in any way. Here is the
reason why, which is very interesting:
So here is the abridged answer to your question:
Sodium channels are responsible for the initiation and propagation of action
potentials. Action potentials are those electrical signals that carry
messages throughout the body whether they be neuronal or cardiac in nature.
Sodium channels go through a basic gating scheme. Upon membrane
depolarization, sodium channels open, or activate, then quickly inactivate
or close. Upon repolarization, sodium channels will go back to the resting
state at which time they are capable of opening again. Channels require a
certain amount of time to recover from inactivation or return to this
available resting state. This recovery from inactivation requires on the
order of 15 ms. The frequency at which action potentials fire is governed by
this recovery. So action potentials can fire about 60 times per second.
Stimulation at higher frequencies would for all intents and purposes drive
those sodium channels near the point of the stimulation into a long lived
inactivated state from which no action potentials could fire. So thus the
reason why lower frequency stimulation would be more deleterious than a 2
kHz frequency.
Larry E. Wagner II
Technical Associate II
Dept. of Anesthesiology
P.O. Box 604
University of Rochester Medical Center
Simply put, your nerves are not fast enough to respond! Does this mean you
are not getting electrocuted? No, but current flow is harmless at these
frequencies. The real danger comes from RF burns, and that is what you will
become aware of the most when you touch the wrong things. Burning flesh
smells awful by the way. When you feel a “tickle” from the PG13 it is either
from a lower frequency component like 60 Hz, or the “tickle” of a nice RF burn.
Yes, they HURT!
Содержание PG13
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