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OM0291 

Page 28 of 56 

Rev 3 November2020 

6.3.6  Terminal Purging and Wipe Down 

Following completion of work, allow the cabinet to run for 2-3 minute period without personnel activity to purge 

the cabinet.  A surface disinfection of the interior surfaces (see Cleaning Procedures section) should be repeated 

after removal of all materials, cultures, apparatus, etc.  A careful check of grills and diffuser grids should be made 

for spilled or splashed nutrients which may support fungus growth and resulting spore liberation that 

contaminates the protected work environment. 

 

6.3.7  Paper Catch/Prefilter 

A permanent paper catch is installed behind the rear divider panel of the work zone.  This area forms the return air 

path to the motor/blower; and if the airflow is blocked, it could seriously affect the performance of the cabinet.  

Therefore, THE PAPER CATCH SHOULD BE CHECKED AND CLEANED ON A MINIMUM OF A WEEKLY BASIS. A daily 

basis if procedures dictate the use of paper products.  Any paper removed must be properly disposed of as 

Contaminated Hazardous Waste. 

 The above procedures also apply to all cabinets configured with a prefilter. 

 

6.3.8  Shut Down 

Turn off blowers and lights.  Do not use cabinet as a depository for excess lab equipment during periods of non-

operation.  If antineoplastic agents are being prepared in the cabinet, it is recommended to let the cabinet run 24 

hours per day.  This lessens the possibility that contaminants may escape. 

 

 

6.4  Ergonomics 

Ergonomics, the study or accommodation of work practices is extremely important for proper cabinet usage and user 

health and safety.  An evaluation of normal work practices should be performed with each user when working in a cabinet.  

Evaluation criteria should be at a minimum: 

 

a.   Proper user posture 

 

b.   Effective work zone layout for work practice 

 

c.   Vision or sightlines 

For each of the above evaluation criterion, several work aids may be supplied to accommodate the user. 

 

Ergonomic chair - A six-way articulating seat and back control for personalized adjustment to assure proper user 

posture.  Be sure feet are resting on the floor, chair foot support or foot rest.  Also be sure back is fully supported 

with proper chair adjustments. 

 

Forearm/elbow support - The cabinet is provided with a non-metallic forearm support on the work access opening.  

Periodic mini-breaks during work practice should be taken resting forearm to avoid stress and fatigue.  Elbow rests 

that can provide support for particular work practices, such as pipetting are optional.  Also available as an option, 

closed cell foam disposable forearm pads to reduce pressure points and add comfort. 

 

Effective workzone layout - Always prepare your work procedure to minimize reach to avoid neck and shoulder 

stress and fatigue.  Rotating tables used to maximum workzone and minimize reach are optional. 

 

Vision and sightline - Always prepare your work procedure to eliminate glare and bright reflections on the window.  

Keep your window clean and sightlines clear to your effective workzone. 

 

6.5  Cleaning Procedures 

 

6.5.1   General

 

Cleaning laboratory equipment is important in terms of both functionality and general good housekeeping. The 

information provided below is intended to aid the development of facility Standard Operating Procedures (SOP’s) 

for cleaning the equipment. It is strongly recommended that all cleaning materials used be tested and verified in 

terms of both effectiveness and material compatibility before they are written into the cleaning SOP 

documentation.  

 

a. The airflow blower should be operating during the cleaning process to maintain sterility and/or containment 

during the cleaning process. 

 

b. Raise window to gain additional access if desired. 

 

c. Apply appropriate cleaning material or surface disinfectant to surfaces. Most surface disinfectants require a 

specific contact time depending the materials used within the work zone. 

CONSULT APPROPRIATE DISINFECTANT 

DOCUMENTATION FOR PROPER APPLICATION AND SAFETY PRECAUTIONS

.  

 

c-1. Stainless steel (type 304) has noted material compatibility concerns with Acids, Chlorides and Halogens. 

IF 

THESE MATERIALS ARE USED AND ALLOWED TO BE LEFT ON THE STAINLESS STEEL SURFACE, OXIDATION AND 

Содержание LabGard NU-640-400

Страница 1: ...Biosafety Cabinet Models NU 640 400 500 600 Bench Console Operation and Maintenance Manual November 2020 Revision 3 NU 640 400 500 600 Series A Manufactured By NuAire Inc 2100 Fernbrook Lane Plymouth...

Страница 2: ...ction from particulate contaminants as prescribed in NSF ANSI 49 Please read this manual carefully to familiarize yourself with proper installation maintenance and operation of the cabinet Other refer...

Страница 3: ...awings are appended in the back flap of this manual along with any modifications and or additions to procedures as outlined in this manual A copy of the original factory test report is also appended t...

Страница 4: ...PA Filter Motor Replacement 7 4 Sliding Window Replacement and Manual Adjustment 7 5 Airflow Control System Setup and Calibration 7 6 HEPA Filter Leak test 7 7 Airflow Smoke Pattern Test 7 8 Site Inst...

Страница 5: ...e see Airflow Schematic and the application of environmental controls as required in the field of biological research or chemical containment The AHBSC when used with proper technique is an effective...

Страница 6: ...pply while specific agents are used o which measures are to be taken in the case of an accident Repairs to the device must be carried out only by trained and authorized expert personnel Keep these ope...

Страница 7: ...OM0291 Page 7 of 56 Rev 3 November2020...

Страница 8: ...291 Page 8 of 56 Rev 3 November2020 2 0 Models and Features The model NU 640 LabGard ES Class II Type A2 Animal Handling Biosafety Cabinet is manufactured in three sizes 4 ft 1 2m 5 ft 1 5m and 6 ft 1...

Страница 9: ...OM0291 Page 9 of 56 Rev 3 November2020...

Страница 10: ...OM0291 Page 10 of 56 Rev 3 November2020...

Страница 11: ...OM0291 Page 11 of 56 Rev 3 November2020...

Страница 12: ...d Shipments 4 1 1 Terms are factory unless stated otherwise Therefore it is important to check each shipment before acceptance 4 1 2 If there is visible damage the material can be accepted after the d...

Страница 13: ...cted should be readily accessible for maintenance purposes Do not position the cabinet to prevent access to the power cord The power cord plug serves as the disconnect and should remain readily access...

Страница 14: ...tionary warning labels that say the following Use of explosive or flammable substances in this cabinet should be evaluated by your appropriate safety personnel Once the determination has been made by...

Страница 15: ...OM0291 Page 15 of 56 Rev 3 November2020...

Страница 16: ...net size reference Electrical Environmental Requirements It is recommended that power to the cabinet whether hardwired or plug connected be on its own branch circuit protected with a circuit breaker a...

Страница 17: ...ment tests The testing methods and equipment required are specified on the factory inspection report included with this manual see insert in back cover NOTE IT IS RECOMMENDED THAT THESE TESTS BE PERFO...

Страница 18: ...987 86 1 4 2190 56 3 8 1433 33 838 78 1 4 1987 86 1 4 2190 68 3 8 1737 33 838 78 1 4 1987 86 1 4 2190 80 3 8 2042 33 838 Work Access Opening Inches mm Standard Opening Height Standard Inflow Velocity...

Страница 19: ...or with solid state DC Motor Controller that provides automatic compensation constant volume control for both filter loading and line voltage variances Monitor and display airflow system performance v...

Страница 20: ...OM0291 Page 20 of 56 Rev 3 November2020...

Страница 21: ...key controls the on off power to the LED light LED above the key indicates full blue for LED light on 6 1 2 4 Ultraviolet UV Light Key Not Available 6 1 2 5 Outlet Keys The outlet key controls the ON...

Страница 22: ...dicate cabinet airflow status During the warm up period the aseptic cleaning process may begin If the sliding window is raised an audible and visual alarm will occur but may be silenced by pressing th...

Страница 23: ...ires the function will turn off Select auto timer duration function o Outlets Press and hold key then press hidden outlet outlet keys sequentially LED indicator above outlet will blink fast Adjust des...

Страница 24: ...n blower hidden keys sequentially Red LED indicator above blower will blink fast Select password Press or key to scroll through the code choices below No Password B B H password B H B password default...

Страница 25: ...ng should be evaluated by appropriate safety personnel 6 2 2 Minimize Penetration of Air Curtain The minimum number of items necessary should be placed into the cabinet to prevent overloading but the...

Страница 26: ...precaution is merely an extension of good aseptic technique as practiced on open bench tops The standard laboratory practices designed to minimize creation and or release of aerosols to the environme...

Страница 27: ...of viable materials should be performed as deeply into the cabinet away from open face as possible 6 3 4 Air Purge Additional purging of the workspace without user activity should be allowed for 2 3...

Страница 28: ...back control for personalized adjustment to assure proper user posture Be sure feet are resting on the floor chair foot support or foot rest Also be sure back is fully supported with proper chair adju...

Страница 29: ...r the purpose of this procedure detailed procedures for cleaning a Class II AHBSC can be found in the 2006 ASHP Technical Assistance Bulletin ASHP Guidelines on Handling Hazardous Drugs2 6 6 2 Procedu...

Страница 30: ...ally decontaminated is known to be biologically clean or known to be chemically inert Surface disinfection is performed as specified in the Cleaning Procedures section Hazardous Gases Personal Protect...

Страница 31: ...n then be activated 8 Seal front and top openings using plastic and tape BE SURE CABINET IS TOTALLY SEALED TO PREVENT ANY LABORATORY EXPOSURE TO DECONTAMINATION GAS 9 Perform decontamination procedure...

Страница 32: ...ow fully exposed for replacement of the filters and motor blower The lowest window position will require the armrest to be removed If the cabinet has the power window option access the Power Window Te...

Страница 33: ...tal Metal NU 640 400 NuAire Part Number A 980979 01 980 00032 01 Filter Size 21 533mm x 44 1118mm x 3 76mm 24 610mm x 30 762mm x 6 152mm Filter Manufacturer Camfil Farr Camfil Farr NU 640 500 NuAire P...

Страница 34: ...e top of the hood Tighten the spring loaded bolts 4 places depressing the gasket material by 1 8 inch 3mm Step 5 Motor Blower Assembly Removal a It is recommended that the motor blower to be removed a...

Страница 35: ...Calibration 7 5 1 General The operation of the NU 640 cabinet requires that the setup and calibration procedures be performed in order to certify or commission the cabinet for usage The setup and cali...

Страница 36: ...light keys will blink fast Review motor control function type and change it desired as described below o Press or keys to scroll through the LED segment choices associated with motor control function...

Страница 37: ...e adjusts or balances the exhaust airflow as well as makes up for filter resistance tolerances Since it has been NuAire s experience that the filters may not load evenly choke adjustments may be neces...

Страница 38: ...eed adjust The red LED will blink as soon as any adjustments are made and will continue to blink as the motor rpm settles Once the red LED stops blinking the motor will run steady state at the new per...

Страница 39: ...stment requires a standard blade screwdriver To adjust loosen the liquid tight fitting around the choke adjustment shaft While monitoring the exhaust flow to check position turning the choke adjustmen...

Страница 40: ...ust be non blinking to save or exit Note At any time during the process Press hidden key to accept low alarm setpoint value Press and hold outlet key for three seconds to remove any previous offsets P...

Страница 41: ...not go through normal start up procedure 7 5 3 5 Nite Care Calibration See Section 8 2 2 to Activate the Nite Care Function The Nite Care mode is defaulted to operate the blower at approximately 600...

Страница 42: ...ocity ft min m s d Acceptance Criteria 1 Average downflow velocity 55 to 65 fpm 28 to 33 m s 2 Individual readings must be within 20 or 16fpm 0 08m s whichever is greater factory test or 25 or 16fpm 0...

Страница 43: ...2 209 315 422 529 636 743 850 957 1064 1171 1278 1384 600 4 8 16 12 32 16 48 20 64 24 80 28 96 33 12 37 28 41 44 45 60 49 76 53 92 58 08 62 28 66 50 102 207 313 419 524 630 736 841 950 1053 1158 1264...

Страница 44: ...typically more difficult to check since protective grills charcoal filters or exhaust transitions could cover the filter Access panels are usually provided and should be removed If an air gap exhaust...

Страница 45: ...4 No smoke shall escape from the cabinet 7 8 Site Installation Assessment Tests These tests are performed to verify the sash position airflow or pressure setpoint where an audible and or visual alarm...

Страница 46: ...t test using non hazardous materials A minimum of three 3 1 minute particle counts shall be sampled and recorded while the user simulates aseptic compounding manipulations At Rest Particle Count Test...

Страница 47: ...20MM NU 640 400 12 AMPS 3 AMPS 2 AMPS 1 AMP 2 2 AMPS NU 640 500 15 AMPS 3 AMPS 2 AMPS 1 AMP 2 2 AMPS NU 640 600 15 AMPS 3 AMPS 2 AMPS 1 AMP 2 2 AMPS 7 10 3 Main Control Board Replacement Note All set...

Страница 48: ...the initial power up the RED alarm LED will blink to indicate power up status 5 Press key to clear the power on reset message 6 Enter into service parameters and input configuration for calibration an...

Страница 49: ...fuse located on main control board Check voltage coming out of main control board Blower or light fuse continues to blow after replacement N A Check for short on output of fuse Isolate output of fuse...

Страница 50: ...must be actively running for the accessary outlet to turn on Sync Outlet Power with Active Blower Normally the outlet power is turned on via the outlet key If the outlet power sync is active the outle...

Страница 51: ...tively running Upon closure the blower will continue to run at a calibrated lower speed level to keep the workzone interior sterile The PresurFlow will indicate s blinking green LEDs along with green...

Страница 52: ...are activated whenever the blower key is pressed and the blower key LED indicator is on or blinking Contact ratings are 250 VAC maximum at 2 Amps 9 2 Alarm Relay The alarm relay contacts are normally...

Страница 53: ...h as hospital and research laboratories and most industrial laboratories the expected transient overvoltage is 2500 V for a 230 V supply and 1500 V for a 120 V supply 10 5 Pollution Degree 2 0 Polluti...

Страница 54: ...ont Grill Stainless Steel Worksurface Stainless Steel Window Faring Stainless Steel Window Glides HDPE Window Safety Glass Window Frame Stainless Steel Front Service Panel Painted Steel Front Decorati...

Страница 55: ...OM0291 Page 55 of 56 Rev 3 November2020...

Страница 56: ...OM0291 Page 56 of 56 Rev 3 November2020...

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