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Idexx Catalyst One, Руководство оператора

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8

Getting Started

Introduction

Welcome to IDEXX’s next-generation chemistry analyzer—the Catalyst One* Chemistry Analyzer. 
The Catalyst One analyzer’s flexible test menu allows you to monitor the health status of specific 
organs, recheck values over time, customize profiles by adding single tests to CLIPs. You can even 
run up to 25 tests

 

on a single sample (for a complete list of the individual slides and CLIPs available, 

see page 12). 
The Catalyst One analyzer is for veterinary use only.

IDEXX VetLab

*

 Station Connectivity

The Catalyst One analyzer is part of the IDEXX VetLab* suite of analyzers, all of which connect 
to the IDEXX VetLab Station (IDEXX’s laboratory information management system). Connecting 
multiple analyzers to the IDEXX VetLab Station helps you attain a comprehensive picture of your 
patient’s health, with the ability to view test results from multiple analyzers on a single report, 
determine disease progression with parameter-trending capabilities, and more.
By connecting the Catalyst One analyzer to the IDEXX VetLab Station, you can: 

•  Automatically review patients’ prior results on every printout for easy comparison.
•  Improve client communications with illustrated diagnostic or treatment progress printouts.
•  Link to expert descriptions and common causes of abnormal values.
•  Print information to help explain the significance of results to your clients.
•  Allow new staff to train independently.
•  Learn proper protocols and tips for best techniques.

IDEXX Dry-Slide Technology

The Catalyst One analyzer uses dry-slide technology—the most accurate technology available for 
in-house testing. Dry-slide technology uses layers to remove impurities for the most accurate results 
from even compromised samples.

Patient sample is applied to 
the top of the spreading layer

Spreading layer 

Sample is distributed evenly

Reagent layer

 

Reagent reacts with sample

Support layer 

Optical interface

Indicator layer 

Reacted sample collects for spectral analysis

Filtering layer 

Filters out substances that interfere with results

Содержание Catalyst One

Страница 1: ...IDEXX Catalyst One Chemistry Analyzer Operator s Guide...

Страница 2: ...yrights or other intellectual or industrial property rights covering this document or subject matter in this document The furnishing of this document does not give a license to these property rights e...

Страница 3: ...ing 14 Diluting Samples 14 Viewing and Printing Test Results 16 Outside of Reportable Range Samples 17 Modifying the Settings on the Analyzer 18 Modifying the Sound Settings 18 Entering Standby Mode 1...

Страница 4: ...nalyzer 28 Cleaning the Outside of the Analyzer and the Sample Drawer 29 Emptying the Waste Drawer 29 Appendices 30 Chemistry Descriptions 30 Medical Protocol Descriptions 51 Profile Selection 56 Diff...

Страница 5: ...ter or other liquids Performance Precaution Do not use certain liquids aerosols such as canned air solvents ammonia and other substances on or near the analyzer which could influence results Care of t...

Страница 6: ...er la notice d utilisation Gebrauchsanweisung beachten Consultare le istruzioni per l uso Consultar las instrucciones de uso Catalog number Num ro catalogue Bestellnummer Numero di catalogo N mero de...

Страница 7: ...el auf elektrostatische Ladung Dispositivo sensibile alle scariche elettrostatiche Keep dry Conserver dans un endroit sec Mantener seco Vor N sse sch tzen Tenere al riparo dall umidit Fragile Fragile...

Страница 8: ...sease progression with parameter trending capabilities and more By connecting the Catalyst One analyzer to the IDEXX VetLab Station you can Automatically review patients prior results on every printou...

Страница 9: ...er measures the color development of the slide and then all used materials are removed from the analyzer Catalyst One Components Front of the Analyzer Side door Sample drawer Waste drawer Inside of th...

Страница 10: ...ts icon on the IDEXX VetLab Station Home screen LED Color Description Green steady READY analyzer is ready to process samples or perform maintenance tasks Green pulse STANDBY MODE Yellow steady IN PRO...

Страница 11: ...bvious sources of heat direct sunlight cold humidity or vibrations For optimum results room temperature should be at 15 C 30 C 59 F 86 F and relative humidity at 15 75 IMPORTANT Ensure proper ventilat...

Страница 12: ...Alanine Aminotransferase ALT Amylase AMYL Aspartate Aminotransferase AST Blood Urea Nitrogen BUN Calcium Ca Cholesterol CHOL Creatine Kinase CK Creatinine CREA Chloride Cl Fructosamine FRU Gamma glut...

Страница 13: ...ep Avian budgerigar cockatoos grey cheek Moluccan umbrella cockatiel canary conure macaw blue and gold hyacinth scarlet parrots Amazon blue Amazon yellow eclectus African grey Monkey Snake Mouse Torto...

Страница 14: ...loaded within 5 minutes of opening their foil packaging The Lyte 4 CLIP should be loaded within 2 minutes of opening its foil packaging If you are running a Lyte 4 CLIP be sure to load it in the sampl...

Страница 15: ...concentration the sample should be diluted manually An automated dilution run will be canceled if There is insufficient diluent sample volume There are too many slides in the run Minimum Sample Volum...

Страница 16: ...6 1 100 L 6 600 L 7 1 100 L 7 700 L 8 1 100 L 8 800 L 9 1 100 L 9 900 L 10 1 100 L 10 1 000 L 11 Viewing and Printing Test Results Analyzer results are automatically returned to the IDEXX VetLab Stati...

Страница 17: ...mmol L 50 160 mmol L 50 160 mmol L CREA 0 1 13 6 mg dL 9 1202 mol L 1 0 136 0 mg L FRU 100 1 000 mol L 100 1 000 mol L 100 1 000 mol L GGT 0 952 U L 0 952 U L 0 952 U L GLU 10 686 mg dL 0 56 38 11 mmo...

Страница 18: ...etLab Station Home screen 2 Tap the Catalyst One side tab 3 If you do not want the analyzer to ever enter Standby mode tap Never in the Standby area OR 4 If you want the analyzer to enter Standby mode...

Страница 19: ...15 CLIP N A NSAID 6 CLIP N A UPC Panel N A Lyte 4 CLIP N A Albumin ALB Alkaline Phosphatase ALKP Alanine Aminotransferase ALT Amylase AMYL Aspartate Aminotransferase AST Blood Urea Nitrogen BUN UREA C...

Страница 20: ...parator except when running feline AST LDH or CK Double dosing may elevate the results for these assays in feline samples 3 Gently swirl do not invert or shake the whole blood separator at least 5 tim...

Страница 21: ...eing used in the run for more information see Proper Sample Cup Volume on page 22 To Prepare a Urine Sample 1 Obtain the sample through cystocentesis recommended catheter or free catch method 2 Transf...

Страница 22: ...rim the serum plasma with a wooden stick respin the sample and proceed Various conditions such as hemolysis may affect results You might also want to modify your test panel based on the following visu...

Страница 23: ...Notes For additional information on the effects of delays in removing serum or plasma from the cells see the Chemistry Descriptions section on pages 30 51 See the calcium Ca total bilirubin TBIL lact...

Страница 24: ...rol vials within 24 hours Expired or unwanted material should be discarded with other clinical waste Note Do not store in the freezer door only in the main freezer compartment Stability and Handling F...

Страница 25: ...uality Control CLIPs and Slides IDEXX recommends that you perform monthly quality control testing after you have cleaned the internal components of your analyzer The convenient Catalyst QC CLIP contai...

Страница 26: ...uent to the control vial using a clean dry Class A volumetric pipette or an equivalent automatic pipette Discard the remaining diluent IMPORTANT Measurement must be precise or results will be incorrec...

Страница 27: ...e cup Note You will need one PHBR slide wash and one PHBR slide for the quality control procedure 4 Run quality control on the analyzer Running Quality Control To Run General Quality Control on the Ca...

Страница 28: ...eaning the Internal Components of the Analyzer To ensure optimal performance of your analyzer it is important that you clean the internal components incubator ring optics window and carousel monthly a...

Страница 29: ...ing near the analyzer organic solvents ammonia based cleaning products ink markers sprays containing volatile liquids insecticides disinfectant polish or room freshener Care should be taken not to spi...

Страница 30: ...therapy However many individual chemistry tests give information about different organ systems and should be used in combination with other tests panels or profiles to help characterize disease Alanin...

Страница 31: ...Sample Type and Precautions Remove plasma or serum promptly from the cells or clot Hemolysis may occur if the sample is not handled properly Although dry slide technology minimizes the interfering eff...

Страница 32: ...be used because ALKP contamination from red blood cells will increase results while hemoglobin decreases results Above normal total bilirubin levels may reduce ALKP results Complementary Tests Alkalin...

Страница 33: ...zed samples Blood samples should be taken within one day of the onset of symptoms that suggest acute pancreatitis Complementary Tests Amylase and lipase are usually determined in conjunction with one...

Страница 34: ...ther tests of liver cardiac or skeletal muscle function or damage Reaction Sequence Blood Urea Nitrogen BUN The catabolism of proteins results in the production of ammonia which is extremely toxic Amm...

Страница 35: ...ith resultant hyperphosphatemia dietary spurious Sample Type and Precautions Remove plasma or serum promptly from the cells or clot If plasma is being collected use only lithium heparinized samples Ce...

Страница 36: ...ium potassium chloride and bicarbonate are measured together accurate assessment of metabolic acid base physiology is possible Reaction Sequence Cholesterol CHOL Serum cholesterol occurs predominantly...

Страница 37: ...and centrifuged immediately after drawing blood Blood samples should be taken within 6 hours of a suspect lesion It is important to determine that the patient has not been exercised vigorously during...

Страница 38: ...s essential for proper interpretation of increases in creatinine Creatinine determinations should usually be performed in conjunction with measurements of BUN inorganic phosphate total protein and alb...

Страница 39: ...rked hemolysis will lower the reported value on the Catalyst analyzers Reaction Sequence Gamma glutamyltransferase GGT The enzyme gamma glutamyltransferase is membrane bound It is present in large qua...

Страница 40: ...te Samples must be centrifuged completely Remove serum promptly from the clot to avoid metabolism of glucose by the cells A maximum of 30 minutes between drawing and separation from the clot is recomm...

Страница 41: ...found in the cell cytoplasm and is released into the blood during reversible and irreversible necrosis cell injury The test is not a specific or sensitive indicator of damage to any organ or tissue No...

Страница 42: ...red cells within 5 minutes of collection Complementary Tests CBC biochemical panel complete urinalysis and blood gas Reaction Sequence Lipase LIPA Lipase is secreted by the pancreas and to a lesser e...

Страница 43: ...nce of measuring serum magnesium concentration in dogs and cats has not been fully investigated However there have been reports of hypomagnesemia in dogs following the removal of the parathyroid gland...

Страница 44: ...y state is achieved timing of sample collection is not important in more than 90 of patients However there can be variability of the phenobarbital half life in a small percentage of patients Therefore...

Страница 45: ...icism Reaction Sequence Sodium Na Sodium is the major cation of extracellular fluid where it maintains osmotic pressure acid base balance and transmits nerve impulses The body maintains total sodium c...

Страница 46: ...d cats the concentration of total bilirubin in the serum is very low Visual inspection of the sample will frequently indicate whether bilirubin determination is necessary serum and plasma only Most Co...

Страница 47: ...If plasma is collected use only lithium heparinized samples Moderate to marked hemolysis can result in false high total protein concentration Results obtained from the analysis of plasma may be slight...

Страница 48: ...in confirming hypothyroidism Cats with consistent clinical signs and total T4 TT4 values in the borderline high range gray zone may have early hyperthyroidism or a concurrent nonthyroidal illness NTI...

Страница 49: ...id prerenal postrenal and renal azotemia associated with decreased glomerular filtration rate Sample Type and Precautions Remove plasma or serum promptly from the cells or clot If plasma is collected...

Страница 50: ...rs to avoid evaporation and contamination Samples may be stored at room temperature for up to 3 days refrigeration preferred Frozen samples can be stored indefinitely Reaction Sequence Urine Protein U...

Страница 51: ...ach tube or gelatin capsules A second sample is drawn 30 minutes after ammonium chloride administration Note Vomiting during the procedure will invalidate results Sample Requirements 1 mL heparinized...

Страница 52: ...igation and management for the underlying cause Renal proteinuria evaluate in the face of azotemia Nonazotemic persistent renal proteinuria dogs and cats UPC 0 5 within reference range UPC 0 5 1 0 que...

Страница 53: ...53 Appendices...

Страница 54: ...ysis Low T4 1 0 g dL 13 0 nmol L Low T4 with NTI 1 0 g dL 13 0 nmol L Normal T4 2 0 4 0 g dL 26 0 51 0 nmol L Hypothyroidism unlikely fT4 TSH TgAA Low fT4 high TSH positive TgAA Hypothyroidism likely...

Страница 55: ...ous Feline hyperthyroidism suspected Normal T4 0 8 4 7 g dL 10 0 30 0 nmol L Low T4 0 8 g dL 10 0 nmol L High T4 4 7 g dL 60 0 nmol L Hyperthyroidism likely Hyperthyroidism unlikely Euthyroid sick or...

Страница 56: ...amples Acute pancreatitis is suspected Renal disease is suspected Chem 17 CLIP Chem 15 CLIP Chem 10 CLIP Gastrointestinal profile Cardiac profile Endocrine profile Hepatic profile Lipid profile Pancre...

Страница 57: ...commercial laboratory as appropriate Each result should have the same relationship to its method s reference range For instance a sample giving a Catalyst One result that is slightly below the Catalys...

Страница 58: ...Free Technical Support 00800 1234 3399 Telephone 34 932 672 660 Fax 00800 1234 3333 idexx es United Kingdom IDEXX Laboratories Ltd Riverside House Riverside Walk Windsor Berkshire SL4 1NA United King...

Страница 59: ...ntie 16 A 3 00100 Helsinki Finland Telephone 0800 98458 idexx fi Norway IDEXX Laboratories Norge AS c o Corpnordic Norway AS v Sunde Bryggetorvet 1 0250 Oslo Norway Telephone 80031026 idexx no Sweden...

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