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negative neutralization capacitance fed back to the probe input) will 
result in a much faster risetime. 
The neutralization control is preadjusted at the factory and in many 
cases will never need additional attention. For very high 
microelectrode resistances (above 10 megohms) or experimental 
setups with a large amount of stray (or a co-axial cable) 
capacitance, slight adjustments from time to time will be desirable. 
Adjustments can be accomplished both when the 2400 is terminated 
in (1) a microelectrode or in (2) a test resistor. 

(1) It may be adjusted during an experiment by simply 
introducing a square wave between the 2400 grounding lead 
(shield of co-axial input cable or mounting rod or bracket) and 
the experiment ground reference wire. Rotate the trimpot until 
the leading edge of the square wave is vertical and displays no 
more RC time constant (exponential) effects. 

 

Actual signals may also be used if it is inconvenient to 
introduce a square wave in the above manner. But because of 
the lack of a clear rise time (or vertical leading edge) in most 
situations the best approach will be to rotate the neutralization 
trimpot until oscillations start, then back off one-half turn. This 
should be very satisfactory in the majority of cases. 

 

(2) The neutralization control may be adjusted to compensate 
for fixed added input capacitance (such as a short length of co-
axial cable from the micro-electrode internal to the 2400 probe 
input connector) in the following manner: Terminate the probe 
input to ground through a 10 megohm resistor (carbon 
composition type may be used). Now rotate the control until 
oscillations are visible at the PREAMPLIFIER output BNC 
connector. Back off one-half turn. This is also a good method 
of calibrating the neutralization control if it is normally not 
used but you desire optimum neutralization. 

 
(b) PROBE INPUT PARAMETERS (PREAMPLIFIER MODE ONLY) 
When operating in the PREAMPLIFIER mode, care should be 
exercised with regard to static voltage discharge to the probe input. 
Although the input is designed around a very rugged dual junction 
FET amplifier and is isolated from the input through a 10K resistor, 
extreme abuse (several hundred volts) may cause some damage. 
The input stage is DC coupled to the microelectrode in the 
PREAMPLIFIER mode (it is disconnected via a reed relay in all other 
modes) and is operated at a gain of 10. For this reason, input DC 
offsets should be less than one volt for linear recording. The use of a 

Содержание 2400A

Страница 1: ...reamplifier Operating Manual Warning This instrument is not designed or intended for use in human applications or human experimentation 111 6008 15813841944 QQ 422612157 0755 28917660 jkang66 163 com...

Страница 2: ...nt Pump 12 a Current Pump Compliance 12 b External Pump Level Reference 12 c Auxiliary Pump Output 13 d Z Test Impedance Test 13 4 Preamplifier 15 a Use of High and Low Cutoff Filters 16 b Monitor Amp...

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Страница 6: ...staining iontophoretic drug injection and as a stimulating current polarize or depolarize In addition the Model 2400Z uses the CURRENT PUMP for microelectrode resistance measurements The 2400 also pr...

Страница 7: ...lection 3 dB points are 0 3 1 0 3 0 10 30 100 and 300 Hz AUDIO MONITOR An internal audio power amplifier monitors the PREAMPLIFIER output Sound level is controlled by the MONITOR control Output is thr...

Страница 8: ...v AC 50 Hz 4 Watts DIMENSIONS MAINFRAME 43 2 cm W 17 X 34 3 cm D 13k X 13 3cm H 5 1 4 for Rack mounting handle and brackets make width 48 3 cm 19 PROBE 5 7 cm 2Y4 X 3 2 cm PA X 2 5 cm 1 less mounting...

Страница 9: ...250v AC range The power supply will operate from 50 or 60 Hz without modification The frequency indicated on the label identifies the frequency of the line notch filter 2 RACK MOUNTING The 2400 is sh...

Страница 10: ...r any future need that you may encounter All this without ever touching the probe or the microelectrode STAIN Your microelectrode recording site can be marked for easy visual identification by using e...

Страница 11: ...o zero nA Supplying an external bipolar analog signal into the EXT REF BNC jack with the PUMP LEVEL switch set to EXTERNAL allows the ideal current source to be programmed externally by the magnitude...

Страница 12: ...T Each 100mV of peak to peak amplitude indicates a microelectrode resistance of one megohm i e 100mV megohm Thus a 20 megohm microelectrode resistance will appear as a 2 volt peak to peak signal Since...

Страница 13: ...In instruments equipped for microelectrode resistance measurements 2400Z the CALIBRATE generator will be modified to a 2 Hz output The model 2400 is normally supplied with a 150 Hz CALIBRATE generato...

Страница 14: ...stance The voltage gain of the preamplifier section is very high switch selection of 50 100 200 500 1 000 2 000 5 000 or 10 000 No other additional amplification should ever be needed between the micr...

Страница 15: ...the preamplifier as a major noise contributor Noise generated by the microelectrode resistance Johnson Noise can also be controlled to some degree by manipulating the bandwidth or frequency response...

Страница 16: ...put never use a MONITOR level so high as to cause oscillation and distortion in its output If the MONITOR amplifier provision is not used the output binding post on the rear panel should not be termin...

Страница 17: ...wo different mating connectors are supplied with the 2400 initially A removable three inch long rod allows the probe to be mounted directly in your micromanipulator A flat removable probe mounting pla...

Страница 18: ...t until oscillations start then back off one half turn This should be very satisfactory in the majority of cases 2 The neutralization control may be adjusted to compensate for fixed added input capaci...

Страница 19: ...mainframe cabinet may be grounded to your experiment for the reference connection The probe is preferable for the lowest noise setup however experimentation with grounding may provide a better noise...

Страница 20: ...ble to connect the microelectrode internal to the 2400 probe input connector To aid in mechanical mounting of the probe either the mounting plate secured to probe by the 4 cover screws or the mounting...

Страница 21: ...120mA and the 15V supply should be capable of supplying 4OmA For battery operation we recommend either four Eveready type 717 batteries 7 5 volts each or four Eveready type 715 batteries The 717 s wi...

Страница 22: ...0 system is warranted to be free from defects caused by materials workmanship and construction for a period of one year from date of purchase During this period Dagan Corporation will service your ins...

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