Bright Instruments 2212 Starlet Скачать руководство пользователя страница 31

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Instruments

Office:

Bright Instruments LTD
Burnett House, Lakeview Court
Ermnie Business Park, Huntingdon
Cambridgeshire, PE29 6UA

Telephone: +44 (0) 808 168 9697
Email: [email protected]

Web: brightinstruments.com
Member:

Cryospray 1234ze

MATERIAL SAFETY DATA SHEET

10. Stability and Reactivity

Conditions to avoid:

Some risk may be expected of corrosive and toxic

decomposition products. Avoid heat, fl ames and sparks.

Materials to avoid:

Reactions with alkali metals.

Hazardous decomposition

products:

Pyrolysis products containing fl uoride. Fluorocarbons.

Hydrogen fl uoride.

Stability and reactivity:

Stable under normal conditions. Hazardous decomposition

products formed under fi re conditions. To avoid thermal

decomposition, do not over heat.

13. Disposal Considerations

Product:

Dispose according to legal requirements.

Contact manufacturer.

Packaging:

Legal requirements are to be considered in regard of reuse

or disposal of used packaging materials.

Further information:

Provisions relating to waste: EC Directive 2006/12/EC;

91/689/EEC Regulation No. 1013/2006.

12. Ecological Information

Persistence and degradability
Biodegradability:

Aerobic. Result: Not readily

biodegradable.

Ecotoxicity eﬀ ects:
Eﬀ ects:

Species:

Value:

Exposure

time:

Comments:

Toxicity to fi sh.

NOEC

Cyprinus Carpio

(Carp)

>117 mg/l

96 h

Toxicity to

aquatic plants.

NOEC

Algae

>170 mg/l

96 h

Growth

inhibition

Acute toxicity

to aquatic

invertebrates.

EC50

Daphnia magna

(Water Flea)

>160 mg/l

96 h

11. Toxicological Information

Acute oral toxicity:

Not applicable.

Acute dermal toxicity:

No data available.

Acute inhalation toxicity:

LC50/rat, value: >207000 ppm, >965 mg/l.

Exposure time: 4 h.

Skin irritation:

Species: rabbit, result: no skin irritation. Method: OECD

Test guideline 404.

Eye irritation:

No data available.

Sensitisation:

Species: human, classifi cation: non-sensitizing.

Further information:

Not mutagenic in Ames Test. May cause headache and

dizziness. No experimental indications on genotoxicity in

vivo found. Detailed toxicological data and examinations,

exceeding the data set in the MSDS are available for

professional users on request.

Содержание 2212 Starlet

Страница 1: ...Instruments Instruments 2212 Starlet Bench Top Portable Cryostat Manual...

Страница 2: ...tion 10 1 2 1 Fitting hand wheel 10 1 2 2 Installation of accessories 10 1 2 3 Insulating plug 11 1 2 4 Positioning 11 1 3 Electrical Connections 11 1 3 1 Settling 11 1 3 2 Electrical requirements 11...

Страница 3: ...hickness across section 23 6 6 Vertical score marks on section 23 6 7 Sections Curling 23 6 7 1 Sections curl over anti roll plate 23 6 7 2 Sections curl under anti roll plate 23 6 7 3 Sections curl u...

Страница 4: ...Bright Instruments 4 SAFETY WARNING Low temperatures are present in this equipment Extreme care should be taken DO NOT let bare skin come into contact with metal surfaces...

Страница 5: ...RNING Extremely sharp knives blades Use knife blade guards at all times Use correct tools for removal and insertion of knives blades DO NOT leave knives blades laying around Place knives blades not in...

Страница 6: ...hould be strictly observed This cryostat is fitted with an in line mains filter which may affect portable appliance test results b Fuses Fuse ratings are clearly indicated on all fuse panels adjacent...

Страница 7: ...wear gloves Avoid touching the knife it is cold as well as sharp ALWAYS use knife guards ACCESSORIES Fluids supplied as accessories with Bright Instruments such as Cryospray 134 Cryo M Bed and microt...

Страница 8: ...riate to his her work Microtomes Knives If decontamination is required carry out the standard procedures as practised in your laboratory It is the responsibility of the customer to use a decontaminati...

Страница 9: ...to a period of six months from the date when the goods shall have been re delivered to the Buyer c This warranty does not apply to any defects caused by wear and tear incorrect installation abnormal...

Страница 10: ...pany Limited immediately 1 2 ASSEMBLY INSTALLATION 1 2 1 FITTING HAND WHEEL MODELS WITH HAND WHEEL ONLY Push the hand wheel over the shaft on the right side of the cabinet Ensure pin on shaft engages...

Страница 11: ...n We recommend the instrument is left standing for at least eight hours and preferably overnight before switching on 1 3 2 ELECTRICAL REQUIREMENTS The supply cord of the instrument should be connected...

Страница 12: ...ation mode is selected in error take the following steps a If Up or Down have not been pressed ie no new parameters have been entered simply leave for 20 seconds Display will revert to normal b If new...

Страница 13: ...e of the holes in the blade appears top sliding by hand Locate the small circular tip of the blade handling device in the hole and slide the blade into position To obtain maximum use of the blade slid...

Страница 14: ...sure that the temperature of the object holder is above zero otherwise the embedding compound will not freeze on it properly Tissue samples are then frozen onto the object holder 34 by placing the ob...

Страница 15: ...JUSTMENT The top edge of the ARP should be just above the blade edge If it is too low the section will curl up and fail to pass between the blade edge and ARP To adjust the height of the ARP turn scre...

Страница 16: ...etting b Swing the anti roll plate into position c Actuate the operating lever hand wheel a slow stroke generally gives good results Experiment to find the most suitable speed Figure 12 d After cuttin...

Страница 17: ...t at night and the defrost duration is sufficient to clear the cooling fins without the rest of the chamber rising above 0 C Figure 13 Set the analogue clock to the actual time by turning the clear pl...

Страница 18: ...the microtome and allow it to warm to room temperature and dry off completely then lubricate the visible screw threads with the low temperature grease supplied e Clean the chamber and dry it off f Se...

Страница 19: ...off its cover b Locate pawl 17 shown on Figs 3 4 c Remove pawl spring locating screw spring and backing plate 97 19 73 d Replace new spring backing plate and locating screw e Check to see if pawl ind...

Страница 20: ...assembly and accessible parts of the microtome are constructed of corrosion resistant materials and the following decontamination procedures can be used Hypochlorite bleach solutions are corrosive to...

Страница 21: ...Ensure all debris is collected and all surfaces have ample contact with the solution e Wipe over again with clean water NB DO NOT use excessive quantities of Virkon solution or water during this proc...

Страница 22: ...p of frost or debris on the blade 6 1 3 ANTI ROLL PLATE a Is it set too high low b Is it parallel to the blade c Is it frosted too warm d Is it damaged section 2 3 6 2 INTERMITTENT FAILURE TO CUT a Bl...

Страница 23: ...i roll plate too warm greasy 6 7 4 SECTIONS CURL AFTER LIFTING ROLL PLATE a Movement too quick delay in collecting sections 6 8 SECTIONS FAIL TO FLATTEN AND PASS DOWN BLADE a Anti roll plate too warm...

Страница 24: ...vent and detergent resistant Cutting Stroke 30mm Maximum Specimen Size 22mm diameter Total Feed Range 10mm Knife Holder Magnacut blade holder with long life disposable blades and integral anti roll sy...

Страница 25: ...tary operation 53559 Spare fuse set for 2212 021 and 2212 001 53560 Spare fuse set for 2212 022 and 2212 002 53569 Spare fuse set for 2212 023 and 2212 003 PRODUCT Code Description 2212 021 Starlet 22...

Страница 26: ...Bright Instruments 26 Material Safety Data Sheets...

Страница 27: ...able miscible in all proportions Transport Information No restrictions Hazards Identification Skin Can cause skin irritation Respiratory May cause difficulty in breathing if exposed to very high conce...

Страница 28: ...as mist vapours spray P308 P313 If exposed or concerned Get medical advice attention P410 P403 Protect from sunlight Store in a well ventilated place Potential Health Effects Skin Rapid evaporation of...

Страница 29: ...avier than air and can cause suffocation by reducing oxygen available for breathing Avoid skin contact with leaking liquid danger of frostbite Use personal protective equipment Keep people away from a...

Страница 30: ...ordance with EN standards respirator EN 136 140 149 safety glasses EN 166 protective suit EN 340 463 468 943 1 943 2 gloves EN 374 safety shoes EN ISO 20345 The type of protective equipment must be se...

Страница 31: ...ng materials Further information Provisions relating to waste EC Directive 2006 12 EC 91 689 EEC Regulation No 1013 2006 12 Ecological Information Persistence and degradability Biodegradability Aerobi...

Страница 32: ...ne Ems number F C S V Marine pollutant No 15 Regulatory information Safety health and environmental regulations legislation specific for the substance or mixture Other inventory information Country Le...

Страница 33: ...n as the decimal sign and its position complies with rules for the structure and drafting of international standards and is a comma on the line As an example 2 000 is two to three decimal places and n...

Страница 34: ...l and chemical properties Form Liquid Density 15 C Kg 1 0 878 Odour Mineral oil odour Colour Pale amber Flashpoint 153 C IP 34PM closed cup Stability and reactivity Stable Yes Conditions to avoid Extr...

Страница 35: ...gest DO NOT induce vomiting Wash out mouth with water SEEK MEDICAL ATTENTION URGENTLY Eyes Flush copiously for at least 15 minutes If irritation persists SEEK MEDICAL ADVICE Fire fighting measures Ext...

Страница 36: ...Bright Instruments 36 References Drawings...

Страница 37: ...Bright Instruments 37 Figure A Quick Freezer Bar QF Bar Lock Pin QF Bar QF Area Microtome Area Object Holder Line drawing or render...

Страница 38: ...Instruments 38 MAGNACUT ASSEMBLY SUB ASSEMBLY 150 122 1 Anti roll Plate Height Adjuster 2 Magnets 3 Anti roll Plate 4 Blade Guard shown open 1 2 3 4 Figure 1 Blade Holder Magnacut blade not shown for...

Страница 39: ...NOT SCALE IF IN DOUBT ASK DECIMAL WHOLE Nos ANGULAR 0 10 0 50 0 5 132 144 24 Knife Angle Adjuster 25 Lock Screw 39 Blade Holder Clamp Knob 24 Knife Angle Adjuster 25 Lock Screw 39 Blade Holder Clamp K...

Страница 40: ...Instruments 40 STARLET MICROTME CALE BT ASK 132 144 14 Ratchet Wheel 17 Pawl 28 Micron Indexing Dial 39 Blade Holder Clamp Knob Figure 4 Coarse Advance Control Figure 5 Section Thickness Control 28 14...

Страница 41: ...4 Ratchet Wheel 17 Pawl 20 Clamp Screw 200 Rotary Main Shaft 203 Coupling Joint 208 Main Shaft Coupler Figure 10 Trimming Figure 11 Trimming STARLET MICROTME HAFT ASSEMBLY 149 74 47 132 60 50 144 DO N...

Страница 42: ...l Assembly Figure 16 Pawl Adjustment 16 Spacer 17 Pawl 19 Pawl Spring 13 Pawl Arm 14 Ratchet Wheel 73 Pawl Spring Backing Plate 97 Screw 107 Roll Pin 17 Pawl 18 Pivot Lock Screw 17 97 19 107 73 16 Cle...

Страница 43: ...place the following part numbers in Fig 3 6 29 30 31 32 33 39 41 47 74 91 92 and 95 200 Rotary Main Shaft Refer to Fig 11 201 Drive Shaft 202 Drive Box 203 Coupling Joint Refer to Fig 11 204 Drive Box...

Страница 44: ...ELSE 0 5mm BK Black BL Blue GY Grey P Pink V Violet Y Yellow BR Brown GN Green OR Orange RD Red W White STARLET 230V DWG 136026 01 ISS Description CN 2 Wiring Connections 3 DEF HTR Fuse 1AT 4 Filter...

Страница 45: ...akeview Court Ermnie Business Park Huntingdon Cambridgeshire PE29 6UA 44 0 808 168 9697 brightinstruments com Member of Instruments Instruments Instruments Instruments Instruments Instruments Agent Di...

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