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21
Too much attachment of fine powder on the filter
may decrease air amount. Press the pulse jet
switch on the key panel to blow pressurized air
into the filter to remove fine powder off. Press the
pulse jet switch at a regular interval to minimize
attachment of fine powder onto the filter.
4. Operating procedures
Operating method
of GB210B
Types and features of binders
(
reference material
)
Types Features
Gelatin
This has only a weak binding force at a lower concentration and high
concentration solution shall be sprayed with humidification.
Dextrin
This has only a weak binding force but is superior in molding capability
into tablets.
Potato starch
This is superior in granule property and inexpensive. Utilized in medical
and food fields.
Sodium alginate
This has a high viscosity and is suitable as a binder mainly used in the
food field.
Gum Arabic
Shall be humidified for spraying. This requires a lot of binder.
CMC (Sodium Carboxymethyl
Cellulose
)
This presents a higher viscosity at a lower temperature. This tends to
leave considerable powder residues.
HPC(Hydroxypropylcellulose)
This is suitable for cohesive, hydrophilic materials.
MC
(
Methyl Cellulose
)
This has a strong binding force and is suitable to those used for
granules coarser.
PVA
(
Polyvinyl alcohol
)
This is superior in granulation efficiency but has some shortcomings in
degradation of granulated substances.
PVP
(
Polyvinylpyrrolidone
)
Those with a higher molecular weight have a strong binding force and
are appropriate for hydrophilic materials.
(3) Follow the same procedures as for the preheating to start
operation of the blower and the heater and start flowing
sample. Adjust air amount with the blower adjusting dial so
that the height of the flow layer coincides with the silicon
cap position on the flow layer chamber.
(4) When the outlet temperature has stabilized, set a spray
pressure and turn the pump FWD switch ON.
Example Spray pressure
0.04MPa
Liquid sending speed:
12mL/min
When flow of sample slows down, turn the pump FWD switch
OFF to reduce spray pressure to minimum.
(Completely shutting spray pressure may cause clogging of
the nozzle.
)
To prevent the nozzle from clogging, use the
pump REV switch to return binder to a point close the tube
connection port on the nozzle. The pump REV switch is active
while it is pressed.
Example Turn the pump switch OFF about 30 seconds after
starting spraying.
Reduce spray pressure to 0.01MPa.
~
Operational hint
~
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Summary of Contents for PULVIS MINI BED GB210B
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