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6 - 4

MIO2 Operating Manual, 394934, en, V3.0

6 - Operation

Operating the MIO2

6.3.6 Incubating

The incubator slots can be operated with different temperatures. 
Validate the temperature profiles before operation.

ATTENTION

Risk of crosstalk. Processes with different slot temperatures not validated 
sufficiently could lead to temperature crosstalk between slots.

Always let one slot unoccupied between two slots operated with high 
temperature gradients.

Heating up

The MIO2 is not suitable for warming up of frozen microplates.

ATTENTION

Risk of error occurrence. The MIO2 is unsuitable for warming up of frozen 
microplates.

Make sure samples and microplates have ambient temperature before 
operation.

ATTENTION

Risk of erroneous results. Highly variable fill levels of microplates may lead to 
temperature gradients between cavities.

Perform process validation to incubate microplates with variable fill levels.

Summary of Contents for MIO2

Page 1: ...MIO2 Operating Manual 394934 en V3 0 Operating Manual Monitored Incubator Option 2 MIO 6 Positions 4 Positions...

Page 2: ...ted from Version Revision Issue Document History 1 0 2007 12 05 New edition 1 1 2009 11 09 Minor corrections 2 0 2010 03 12 Added the 4 slotted monitored incubator 2 1 2014 08 07 Added the installatio...

Page 3: ...tions 1 4 2 Safety 2 1 Safety Message Conventions 2 1 2 1 1 Signal Words 2 1 2 1 2 Safety Symbols 2 1 2 2 General Safety Information 2 2 2 3 Operating Company 2 3 2 4 User Qualification 2 3 2 4 1 Oper...

Page 4: ...rating Elements 6 1 6 3 Operating the MIO2 6 2 6 3 1 Safety Instructions 6 2 6 3 2 Process Validation 6 2 6 3 3 Switching the Incubator On 6 3 6 3 4 Switching Incubator Off 6 3 6 3 5 After an Aborted...

Page 5: ...r more information on the software please consult the corresponding software manual Refer to section 1 7 Reference Documents 1 2 1 1 Scope of This Manual This manual is applicable for MIO2 6 positions...

Page 6: ...of safety and compliance to national and international standards as required for UL CSA certification by EC directives etc 1 6 Trademarks The product names whether registered or unregistered trademark...

Page 7: ...ent Software Manual Doc ID 392888 Fluent Instrument Software Manual Doc ID 396330 1 7 3 Other Reference Documents Certificate of Decontamination Form Doc ID 40205TMt01 1 8 Compliance with Laws and Sta...

Page 8: ...1 4 MIO2 Operating Manual 394934 en V3 0 1 About This Manual Abbreviations 1 10 Abbreviations FSE Field service engineer MIO Monitored Incubator Option...

Page 9: ...zards associated with the use of the MIO2 2 1 Safety Message Conventions 2 1 1 Signal Words WARNING indicates the possibility of personal injury or even loss of life if the instructions are not follow...

Page 10: ...difications to the system may only be performed by an FSE certified for the repair and upgrading of the MIO2 Tecan will reject any claim resulting from unauthorized modifications Fire hazard caused by...

Page 11: ...before removal 2 3 Operating Company The operating company must ensure that the MIO2 and in particular the safety features function properly and that all the personnel in contact with the instrument a...

Page 12: ...tion or system knowledge Command of local languages Command of English is preferable The operator has application software access rights allowing him to run methods and perform system care 2 4 2 Key O...

Page 13: ...lage etc Before returning the MIO2 or its parts or accessories to Tecan e g for repair Prior to storage Prior to disposal In general before moving the MIO2 or its parts from its location The owner of...

Page 14: ...2 6 MIO2 Operating Manual 394934 en V3 0 2 Safety Decontamination Declaration...

Page 15: ...s provided in a 4 and a 6 slot configuration with the following features Standard The standard configuration does not contain the shaking option Shaking Incubator Both incubators can be equipped with...

Page 16: ...y It is recommended that theMIO2 is only delivered and installed by Tecan authorized field service engineers 3 2 Product Identification and Appendix Labels 6 Slot MIO Fig 3 2 MIO2 6 positions product...

Page 17: ...ct identification and appendix labels Calibrated at XY C INCUBATOR MIO2 4 Slot XY C 300YYYYY 24VDC 150W T8A Fuse P U f REF Model 1001 SN 300YYYYY 1001 C B A D E A Product identification label B Calibr...

Page 18: ...ensions of the MIO2 6 positions Dimensions Value La Length of standard configuration 213 mm 8 38 in Lb Length with shaking assembly fan option configuration 265 mm 10 43 in W Overall width 130 5 mm 5...

Page 19: ...shaker option Tab 3 4 Dimensions of the MIO2 4 positions Dimensions Value La length of standard configuration 228 mm 8 98 in Lb length with shaking assembly fan option configuration 278 mm 10 95 in W...

Page 20: ...ax 2 C at 60 C max 3 6 F at 140 F Warm up time from 20 C to 37 C max 20 min Warm up time from 20 C to 45 C max 20 min Warm up time from 20 C to 60 C max 30 min Shaking rotation fre quency 1 8 5 Hz Lin...

Page 21: ...amplitude in Y dimension Tab 3 7 Operating ranges 4 positions Tab 3 8 Operating ranges Connector 9 pin sub D CAN Bus Power consumption 150W 90W a a Setup in current limitation mode with the Instrument...

Page 22: ...e MIO2 is used with Refer to section 1 7 Reference Documents 1 2 MIO2 must be protected against dust and debris with a cover Only store MIO2 in its original packaging 3 8 Emissions Refer to the operat...

Page 23: ...n Purpose of This Chapter This chapter explains the basic principle of the MIO2 shows how it is structured and gives a functional description of the assemblies 4 1 Principles of Operation The MIO2 con...

Page 24: ...microplates from dislocating Heating devices provide uniform temperatures Adjustable stands Three adjustable stands provide correct positioning and aligning on the instrument work table Shaker The sh...

Page 25: ...Option Before you completely unpack the MIO2 check the following Is the packaging damaged in any way Is there any damage visible on the device Is the material complete according to the Order Configura...

Page 26: ...formation on the material used for this packag ing is provided beneath the symbol This side up Ensure that the package is transported and stored with the top side indicated by the arrows uppermost Do...

Page 27: ...he incubator ATTENTION Risk of damage to equipment Incubators that are installed in disorder will lead to damage to equipment Make sure that the incubators are in correct order if multiple incubators...

Page 28: ...e One or two MIO2 can be connected in series CAN and have a device address switch each 1 Connect the interface cable D sub connector A to the incubator and tighten the connector s fixing screws If ins...

Page 29: ...rocedure in the current limitation mode Refer to the Instrument Software Manual for further information 3 Perform the setup procedure with the Instrument software ATTENTION Risk of malfunctions An inc...

Page 30: ...he incubator 1 Put the incubator A on the support plate Fig 5 4 5 6 Note Make sure that the feet rest precisely in the designated positioning cavities of the support plate 2 Use the special tool D to...

Page 31: ...om the perpendicular line must not exceed 0 3 mm ATTENTION Risk of foreign object damage Foreign objects brought in between the support plate and instrument worktable may lead to damage to equipment M...

Page 32: ...5 8 MIO2 Operating Manual 394934 en V3 0 5 Installation Incubator Installation...

Page 33: ...es on the PC Depending on your application refer to the relevant separate documentation 6 2 Display and Operating Elements There are no display elements attached directly to the MIO2 The corresponding...

Page 34: ...riate safety precautions according to local state and federal regulations Handling and disposing of waste must be in accordance with all local state and federal environmental health and safety laws an...

Page 35: ...een loaded into the incubator WARNING Injuries or contamination with hazardous materials possible if the maintenance is not carried out properly Make sure that the instrument worktable and the MIO2 ar...

Page 36: ...slots Always let one slot unoccupied between two slots operated with high temperature gradients Heating up The MIO2 is not suitable for warming up of frozen microplates ATTENTION Risk of error occurre...

Page 37: ...ned by the key operator based on the type of contaminant and degree of contamination Guidance on the selection of decontamination agents and application modes is provided in this chapter 7 2 Cleaning...

Page 38: ...aintenance tasks Once installed the MIO2 is part of the instrument Decontaminate and clean the MIO2 when decontaminating and cleaning the instrument For detailed information on maintenance of the inst...

Page 39: ...o equipment Make sure no foreign objects get caught in the incubator slots WARNING Fire hazard caused by the improper cleaning Some cleaning agents are flammable liquids Let MIO2 cool down completely...

Page 40: ...7 4 MIO2 Operating Manual 394934 en V3 0 7 Maintenance Special Maintenance Tasks...

Page 41: ...e MIO2 It lists possible occurrences their probable cause and suggests how to remedy the problem Which Errors can the Operator Correct The troubleshooting table below lists possible malfunctions and e...

Page 42: ...nd PC Notify your local service organization Shutter does not close properly Mechanical failure of the shutter locks Perform shutter test refer to Instru ment Software Manual Notify your local service...

Page 43: ...Disposal ATTENTION Recycling in accordance with applicable legal regulations Observe the laws applicable in your country for recycling For further information refer to the Operating Manual of the ins...

Page 44: ...9 2 MIO2 Operating Manual 394934 en V3 0 9 Disposal...

Page 45: ...Contact your local distributor or one of the addresses below Also see our homepage on the web www tecan com Country Region Address Telephone Telefax E mail Asia Tecan Asia Pte Ltd 18 Boon Lay Way 10...

Page 46: ...can Benelux B V B A Industrieweg 30 NL 4283 GZ Giessen Netherlands Phone Fax E mail 31 20 708 4773 31 183 44 80 67 helpdesk benelux tecan com Scandinavia Tecan Nordic AB Sveav gen 159 1tr SE 113 46 St...

Page 47: ...t Contacts MIO2 Operating Manual 394934 en V3 0 10 3 USA Tecan Systems Tecan Systems Inc 2450 Zanker Road San Jose CA 95131 USA Phone Fax E mail 1 408 953 3100 Toll Free 1 800 231 0711 1 408 953 3101...

Page 48: ...10 4 MIO2 Operating Manual 394934 en V3 0 10 Customer Support Contacts...

Page 49: ...ents 3 7 EVOware 3 7 Freedom EVOlution 3 7 Instrument Software 3 7 E Electrical specifications 3 7 Environmental conditions 3 8 P Packaging 5 1 Product Identification 3 3 Barcode 3 3 Calibration Label...

Page 50: ...11 2 MIO2 Operating Manual 394934 en V3 0 11 Index...

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