Rev 002, 01/14
9
© SP Scientific 2014
Chapter
3
Basic Operation
Getting Started
Prior to operating your freeze dryer, ensure that your condenser is clean, dry and
empty.
Product Preparation: Flask/Manifold Drying
BenchTop Pro units include Quickseal valves for processing samples using flasks or
other glassware.
To prepare samples for freeze-drying in glassware:
Fill flasks with your product.
3
Do not fill more than half of the flask’s total
1.
capacity. When using Wide Mouth Flasks, ensure that the filter paper and
O-ring are positioned correctly within the flask cover. Snap the cover securely
onto the flask.
4
Pre-freeze product samples in a laboratory freezer, dry ice bath or shell bath
2.
freezer. Freezing to -40 °C is adequate for most products.
5
Product Preparation: Drum Manifold Shelf Drying
As an alternative to using flasks, you may use an optional drum manifold and racks to
dry vials of product.
To prepare samples for rack drying:
Fill vials or other suitable containers with product.
3
Do not fill containers to
1.
more than half of their total capacity.
Pre-freeze product samples. This can be accomplished directly in the
2.
condenser of BenchTop Pro 3L and 8L units, or in a laboratory freezer, dry ice
bath or shell bath freezer. Freezing to -40 °C is adequate for most products.
5
Note: Pre-freezing directly in the condenser cannot be done in a BenchTop Pro 9L
unit.
If your unit is equipped with the Stoppering-Tainer and you are processing
3.
product in vials, partially insert a split rubber stopper into each vial.
Load samples onto the shelf (or shelves). If you are using product probes,
4.
connect the probes to the thermocouple jacks provided.
3
Refer to Appendix B for a list of standard serum vial capacities.
4
Wide Mouth Flasks are the most popular glassware type, but other types of flasks, vials and ampoules are available. If you are
not certain how to use glassware accessories, contact SP Scientific.
5
Dry ice methods can freeze a product to approximately -78 °C, while liquid nitrogen (N
2(liq)
) methods can freeze a product to
approximately -190 °C.
Summary of Contents for VirTis BenchTop Pro Series
Page 1: ...FREEZE DRYER OPERATOR S MANUAL VIRTIS BENCHTOP PRO FREEZE DRYERS...
Page 2: ......
Page 6: ...iv Rev 002 01 14 SP Scientific 2014...
Page 22: ...Basic Operation VirTis BenchTop Pro 14 Rev 002 01 14 SP Scientific 2014...
Page 30: ...Accessories and Options VirTis BenchTop Pro 22 Rev 002 01 14 SP Scientific 2014...
Page 38: ...Appendix B Serum Vial Capacities VirTis BenchTop Pro 30 Rev 002 01 14 SP Scientific 2014...
Page 40: ...Appendix C Stainless Steel Cleaners VirTis BenchTop Pro 32 Rev 002 01 14 SP Scientific 2014...