Table of Contents
Chapter 1: Hemostasis and Why We Care About It in Cardiopulmonary Bypass Surgery
1-1
Overview 1-1
Hemostasis Management Testing Needs
1-1
Hemostasis Management and the Sonoclot Analyzer
1-1
Chapter 2: Hemostasis Fundamentals
2-1
Hemostasis Basics
2-1
Fibrin Gel Formation
2-3
Clot Retraction, i.e. Platelet Function
2-3
Fibrinolysis 2-3
Chapter 3: Evaluating Global Hemostasis with the Sonoclot Analyzer
3-1
The Sonoclot Analyzer Principle of Operation
3-1
Sonoclot Signature
3-1
Sonoclot Analyzer Quantitative Outputs
3-2
Sonoclot Signature Phases
3-2
Chapter 4: Heparin Management in Cardiopulmonary Bypass Surgery
4-1
Heparin 4-1
Heparin Effects on Coagulation
4-1
Heparin Management Objectives
4-2
Activation Reagents for Heparin Monitoring
4-2
Pre Bypass: Baseline
4-4
On Bypass: High Dose Heparin Therapy
4-4
Post Bypass: Heparin Reversal and Hemostasis Restoration
4-4
Platelet Function
4-5
Chapter 5: References and Further Reading
5-1
Chapter 6: Technical Support
6-1
Contact Information
6-1
Exporting Signature Groups from Signature Viewer
6-1