background image

Multi-Echo EPI 

Page 4 of 9 

Numaris/4 VA21B 

1.2  Image contrast of Multi-Echo EPI 

 
The signal intensity of the single echo images of the Multi-Echo EPI sequence is 
simply given by: 
 

*)

2

/

exp(

0

T

TE

S

S

=

 

 
where 

S0

 is the signal intensity at echo time 0, which corresponds to the proton 

density for long repetition times 

TR

, and 

TE

 is the echo time. Therefore, the echo 

times of the different echo-images should be on the order or less than the tissue T2*. 
Parametric images of the proton density and T2* can be obtained by fitting a model 
function to the signal intensities at the different echo times (3). Please see the 
processing options described below. 
 

 

 

 

Figure 2

 – Head images acquired on Magnetom TRIO with the Multi-Echo EPI 

sequence with 4 different echo times in a single shot. 
 

 

1.3 Processing options 

 
Several processing options are given in the method. The different echo images are 
always saved separately as the original images and optionally parametric maps can 
be calculated in the reconstruction. In addition, online 3D-motion correction (even 
prospective – PACE) and t-test can be performed. Please see sequence and 
protocols for details. 
 
 

1.4 References 

 

1.  P. Mansfield, A.A. Maudsley. Planar Spin Imaging. J. Magn. Reson. 27, 101 

(1977) 

2.  O. Speck, J. Hennig. Functional Imaging by I

0

- and T

2

*-Parameter Mapping 

using Multi-Image-EPI. Magn. Reson. Med. 40(2), 243-248 (1998) 

Summary of Contents for MULTI-ECHO EPI 4A21

Page 1: ...etom under VA21B Installation and User s Guide NUMARIS 4A21 April 4th 2003 Section of Medical Physics University Hospital Freiburg Germany Contact Oliver Speck PhD Hugstetterstr 55 D 79106 Freiburg email oliver speck uniklinik freiburg de phone 49 761 2703832 ...

Page 2: ...ciple of Multi Echo EPI 3 1 2 Image contrast of Multi Echo EPI 4 1 3 Processing options 4 1 4 References 4 2 Software Installation Procedure 5 2 1 Installation 5 3 Sequences and Protocols 7 3 1 General Remarks 7 3 2 New Parameters 7 3 3 Remarks on reconstruction performance 9 3 4 Protocols 9 ...

Page 3: ...se gradient is rewound to the original starting position after each echo image to ensure identical k space trajectories for all echo images 2 GP RF GS GR echo image loop n Figure 1 Basic timing of the Multi Echo EPI sequence The shaded gradient in phase encoding direction ensures identical k space trajectories for all echo images The resulting echo images have different increasing echo times and t...

Page 4: ...ifferent echo times 3 Please see the processing options described below Figure 2 Head images acquired on Magnetom TRIO with the Multi Echo EPI sequence with 4 different echo times in a single shot 1 3 Processing options Several processing options are given in the method The different echo images are always saved separately as the original images and optionally parametric maps can be calculated in ...

Page 5: ...mepi2d_VA21 m750 n4 ppc750 prod bin Attention This is only correct for systems with Reco PC and m750 MPCU Otherwise copy the relevant MPCU file to the corresponding directory Software does not run on Alpha reconstruction machines CoilSelectManipulator h ist ein noch fehlendes File in C idea n4 comp Measurement CCSpuSer CoilInterface Copy the EVA program dll files to the customer EVA directory copy...

Page 6: ...Multi Echo EPI Page 6 of 9 Numaris 4 VA21B ...

Page 7: ...tor will sometimes not allow the measurement to be performed with the parameters selected In general a lower bandwidth will decrease the stimulation and a different selection of the readout gradient may also help read direction along L R axis shows generally the lowest stimulation 3 2 New Parameters Number of echoes The number of echo images per excitation can be set on the sequence card part1 as ...

Page 8: ... set to 334ms to avoid very large signal intensity differences in case of fitting errors and allow a T2 resolution of 0 1ms without overflows Therefore T2 maps of phantoms with very long T2 and good homogeneity may be calculated falsely The T2 fit is only performed when Mosaic images are created for more than 1 slice Motion Correction Similar to the motion correction in the a_ep2d_mosaic sequence ...

Page 9: ...re long reconstruction times after the scan are possible The scan is not aborted However no new scan can be started during reconstruction Do not move the patient table to the home position during reconstruction otherwise the reconstruction will stop and data is lost The number of images that can be processed online depends on the reconstruction hardware Up to 20 slices with 4 echoes and a TR of 3s...

Reviews: