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Appendix
A.3 Creatinine Methodology
The creatinine measurement is based on the following
methodology:
Enzymes
1. Crea O
2
–––––––––> H
2
O
2
Enzymes
2. H
2
O
2
+ Ferrocyanide –––––––––> Ferric H
2
O
-e
-
3. Ferricyanide –––––––––> Ferrocyanide
Electrode
The current generated at the electrode is proportional to the
creatinine concentration of the sample.