Galvanic Applied Sciences AccuChrome MA2963, Operation Manual

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Revision 4 87 12/15/2018
7.5
Remedial Activities if the Observed Results do not Meet the Certified Values
If the results are not within specification, the following steps should be taken:
a) Verify that the carrier gas pressure is set correctly. The correct setting for the carrier gas
is and is also indicated on the carrier gas regulator’s pressure gauge. If the pressure is
not set correctly then it should be adjusted.
b) Verify that the oven temperature is at the correct set point. The correct set point of the
oven is of this manual.
c) Verify the timing of the integration of each peak on the chromatogram. Each peak should
be analyzed to ensure that the integration parameters are set correctly and that there has
not been any retention time drift that may affect the way the peak is integrated.
d) Compare the actual retention time of the peak to theoretical retention time. The actual
retention time can be determined by setting the mouse pointer at the top of the peak on
the chromatogram.
e) Check the integration marks for each peak on the chromatogram which indicate where
the integration for each peak starts and ends. The marks should include the entire peak.
If the marks show that only part of the peak is being integrated, then the integration
parameters in the Component Table should be observed and corrected.
f) Make certain that the
Skimming Parameters
for each peak are rational. Skimming
parameters are used to indicate the window in which the minimum before the peak and
after the peak are to be found and are listed in the Configure G.C. table (Figure 7-2). The
windows for a typical peak is shown in Figure 7-3.
Figure 7-2: Configure G.C. Table