Flowonix PROMETRA REF 91825, Manual

Page: 14 / 60

Page 8 REFILL KIT, For use with Prometra
®
Programmable Infusion Systems
English
Instructions
Filling the Drug Refill/Reservoir
9. When refill of the drug reservoir is completed, maintain downward pressure on the syringe plunger,
clamp the extension tubing, and remove the needle from the refill septum. Discard the tubing,
syringe and the needle.
Caution: Do not rock the needle sideways as this may damage the pump or cause drug to leak into
the pump pocket.
10. Using the Prometra Programmer, program the empty and refill information into the pump. If the drug
flow rate has been changed, program the new drug flow rate.
Caution: Always program a dose of 0.1 mg/day or greater to maintain catheter patency.
11. If you have changed drug concentration, you must calculate and program a bridge bolus to deliver
the residual drug in the pump and implanted catheter at the new rate. Refer to the supplementary
Calculations Guide to make this calculation and to the Catheter Access Kit instructions for use to
perform the bridge bolus(es).
12. Once the bridge bolus(es) is completed, the new drug regimen starts, using the new drug
concentration in the reservoir.
Suspending Drug Therapy - Pump Rinse
Always empty then flush the pump twice with two 20mL volumes of sterile preservative-free 0.9% saline
when suspending drug therapy. It is important to empty and flush the pump twice to dilute residual drug
left in the pump to non-therapeutic levels.
1. USE STERILE TECHNIQUE. Always inspect and aseptically prepare the site according to standard
practice.
2. Before refilling or suspending drug therapy of the Programmable Pump, the drug refill/reservoir must
be emptied. Refer to Emptying instructions.
3. If required, drug remaining in Intrathecal Catheter and Catheter Fluid Pathway can be removed via
aspiration. Refer to the Catheter Access Kit instructions for use to perform the aspiration.
Warning: If the Catheter Access chamber is not aspirated the drug in the pump fluid pathway and
catheter will be administered to the patient at the flow rate programmed after the pump rinse.
Warning: After aspiration, the pump fluid pathway contains approximately 0.137 mL of drug at the
concentration previously in the reservoir. This volume of drug will be administered to the patient at the
drug flow rate programmed into the pump after pump rinse. Refer to the Calculations Guide for more
information.
4. Fill a 20 mL syringe with sterile preservative-free 0.9% saline solution.
5. Attach 0.22 micron filter to the saline-filled syringe and prime the filter with saline to remove air.
Confirm that the syringe still contains 20 mL, the reservoir volume of the pump, or fill with sterile
preservative-free 0.9% saline solution to 20 mL.
6. Attach the filter-syringe assembly to the extension tubing already attached to the needle in the pump.
Verify that there is no air in the system. Set aside this Pump Rinse setup.
7. Open the extension tubing clamp. Keep downward pressure on the needle and begin slowly infusing
the saline solution into the drug reservoir. At every 5 mL increment, release pressure on the syringe
plunger to allow 1 mL of saline back into the syringe. This will verify that the needle is in the correct
position and drug reservoir is being filled.
Caution: If the sterile saline solution does not return back into the syringe when pressure to the syringe
plunger is released, do not continue to infuse until proper placement of the needle has been verified.
8. When all of the saline solution is in the pump reservoir, allow the contents of the pump to empty back
into the 20 mL syringe. When the pump is empty, clamp the extension tubing.
9. Disconnect the syringe and discard the saline.