FagronLab PRO, User Manual

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FagronLab™ PRO – User Manual | 26
FagronLab™ PRO
Crystalline active substances
We recommend pulverizing active crystalline ingredients in a mortar prior adding into the jar to avoid complex post processing
(e.g. ointment mill). Should a solvent for the active crystalline component be part of the formulation, the ingredient may then also
be dissolved in the jar, for example urea with water.
Then the remaining formulation component/s can be added. If the solvent is in sufficient amounts a component of the ointment
foundation the crystalline substance may dissolve during the mixing process.
Components to be melt
Components, that have been weigh out to fuse, may be placed inside a jar, douse with heated aqueous or oily phases of the
formulation components (< 85 °C / 185 °F) to melt the content in full.
In case this process does not sufficiently melt all the components, the formulation inside the jar might be heated in a warm water
bath (< 85°C / 185 °F) or carefully observed in a microwave oven. In order to avoid overpressure in the jar remove the red cap of the
jar lid.
Formulations, without water containing components, may be melted directly inside the jar by placing the jar in a warm water
bath.
Please be aware that stirrers must not go into the microwave oven! Furthermore, due to irregular mixing of oily and water phases,
reaching the melting point might happen with a delay, since only aqueous phases will be heated by microwaves.
Please consider also the operation manual of the used microwave oven! An excessive temperature rise for both, jar and its content,
must be avoided all the time!
The cooling time and the cooling interval can be decreased by using a refrigerator or a cooling cuff. The stirrer should remain in the
jar during the cooling phase.
Thermolabile substances
Active substances or components with thermolabile characteristics should be processed with caution. To protect the substances,
we recommend a maximum speed of 1200 rpm (level4). To control the frictional heat, a cooling cuff can be used or a cool down
interval in a refrigerator if required.
After the mixing process is complete
After finishing the mixing process the mixing unit will be released and can be removed from the lift arm. Unscrew the jar from the
lift arm, this will only require a quarter turn clockwise.
In the next step, the jar lid should be opened and the stirrer removed. Since this is also an opportunity, execute an organoleptic
quality check, the jar lid should also be opened after mixing when using the Disp. Blade.
Practice has proven that if the surface of the compound looks smooth and consistent, complying with the minimum defined
mixing time, homogeneity inside the jar also can be expected for the entire product.
Afterwards slide the stirrer out of the jar lid. The ointment on the stirrer can be cleaned off into the jar by using a spatula. When
using the Disp. Blade, the stirrer can be removed from the jar and disposed, or left inside the jar.
Leaving the blade inside the jar will have no effect on dispensing the ointment through the jar lid. Removal of the disposable
mixing blade is recommended, particularly when giving the ointment to elderly clients, since it might otherwise cause confusion if
the ointment is traditionally dispensed.