MNL-00024 [1]
Proprietary and Confidential
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15.3
Daavlin Dose Patch (sold separately)
The Daavlin Dose Patch is a disposable adhesive MED/MPD test panel. There are six exposure windows
measuring 2cm x 2cm. The panel is applied directly to the patient’s skin like a bandage. The Dose Patch
is hypoallergenic and can be used for all skin types.
15.4
General Instructions for MED Testing
Dose Patch can be used on any part of body. Non-exposed areas of
arms, buttocks and back are common test sites. Protect the patient’s
eyes and cover areas not being tested with UV blocking clothing or
sunscreen. The person doing the testing should also take protective
measures against incidental exposure.
Remove the two adhesive end pieces on the back of the patch. Apply
the patch in the desired location. Make sure it is stretched tightly across
the skin. Use two or more patches if more than six exposure levels are
required.
Determine the doses you will test for (recommended doses below).
Open exposure window #1. Begin the test by exposing entire patch
area to ultraviolet light source. As each dose level is reached, open
exposure windows in consecutive order. The last window opened equals the lowest dose; the first window
opened equals the highest dose.
The patient will need to return in 48 hours to have the test results read for UVA-1. The resulting MED will
now be the initial MED for setting up the patient for the first treatment.
15.5
RECOMMENDED PROTOCOL FOR UVA-1
Irradiation 5 x week for 3 weeks (altogether 15 exposures) Determination of the UVA 1 MED prior to
treatment Start with 1 MED if MED < 70 J/cm2. Increase of the dose by 20 % every time if there is not an
erythematous reaction and by good tolerability until a maximal dose of 70 J/cm2.
NOTE: REFERENCE THE APPLICABLE TIME CHARTS SUPPLIED WITH YOUR ML24000 FOR DOSING TIMES
Daavlin Dose Patch
