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Protocol pre-set thresholds
Below is an interpretation table for general guidance on interpreting the H
2
values for supporting a
diagnosis of conditions. Other factors through qualified judgement need to be taken in account by looking
at the patient history, on-going symptoms and symptoms during test. H
2
readings can be
interpreted as positive or negative using the following pre-set thresholds (this is the increase in
reading compared to the base sample):
Test
Positive interpretation
Lactose
2,3
H
2
>20ppm CH
4
>12ppm compared to base sample
Lactulose
4
H
2
& CH
4
>20ppm compared to base sample within 90 minutes of lactulose ingestion
Lactulose
2
SIBO*
a) Early increase of at least 20ppm for the sum of the two gases
b) Increase >20ppm corresponding to the appearance of lactulose in the colon
Lactulose
2
IITT**
Fast >20ppm peak is detected at 60 minutes
Normal >20ppm peak is detected at 80 minutes
Slow >20ppm peak is detected 100 minutes or later
Fructose
2
H
2
>20ppm CH
4
>12ppm compared to base sample
Sorbitol
3
H
2
>20ppm compared to base sample
Xylitol
3
H
2
>20ppm compared to base sample
Glucose
3
H
2
>10ppm CH
4
>10ppm compared with base sample
*SIBO = Small Intestinal Bacterial Overgrowth
**IITT = Impaired Intestinal Transit Time
Summary of Contents for Gastro+ Gastrolyzer
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