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Table 3. Periodic 2320EXT calibration and maintenance Schedule for cGxP environment* 

Task 

Weekly 

Monthly 

Annually 

 Inspect the System Log for critical errors 

 

 

 

Inspect the remaining hard disk storage and perform data backup.

 

 

 

Inspect Windows Embedded Standard Event Logs for critical 
errors 

 

 

Check and correct MS Windows Date/Time settings  

 

 

Run MS Windows Update routine, if system is not connected to 
the network or not configured to receive automatic updates.  

 

 

 

Calibration (OQ) of Pressure transducer and temperature control 

system relative to the appropriate NIST-traceable external 
devices.

 

 

 

* Recommended minimal intervals only. Adjust according to your local institution policies. 

 

 

Содержание Barocycler 2320EXT

Страница 1: ...320EXT Pressure Cycling Technology PCT Sample Preparation System Operator s Manual Operator s Manual Version 2 4 June 2017 Pressure BioSciences Inc 14 Norfolk Ave South Easton MA 02375 508 230 1828 ww...

Страница 2: ...ion owned by Pressure BioSciences Inc that covers the Pressure Cycling Technology Sample Preparation System any composition reagent or kit or any process Specifically but without limitation no right i...

Страница 3: ...zardous currents and voltages may be present inside the unit The pressure vessel hardware may be hot when operating at high temperatures Appropriate personal protection insulating gloves or glove line...

Страница 4: ...13 3 2 Advanced Features of the 2320EXT Software 18 3 3 User Management GLP GMP and Electronic Records Compliance 21 4 Maintenance 23 4 1 General Maintenance 23 4 2 Confirm Quality of Compressed Air...

Страница 5: ...ct the power interface cables and operate the instrument This symbol on the instrument states that high voltage or high current may be present when panels covers are removed Any adjustment maintenance...

Страница 6: ...ctions and diagnostic error messages see the troubleshooting guide Section 5 The chamber closure features an internal check valve that is used to allow air or residual pressure to be purged from the c...

Страница 7: ...onnected to a water bath is achieved via the water bath controller and cannot be set via the 2320EXT software When connected to a circulating water bath the 2320EXT WJ chamber can be heated up to 95 C...

Страница 8: ...edded NOTE Automatic Logon for Default User is disabled on 2320EXT Software v1 3 5 1 and higher Administrator must set up user community Default user cannot use the system Non default users must have...

Страница 9: ...n temperature can be set in the range between room temperature and 95 C Note that the 2320 EXT is not equipped with a built in chiller Setting temperature to below ambient will not result in chamber c...

Страница 10: ...r in order to distribute force evenly on the connector screw Avoid using fewer than 4 tubes per cartridge as this may result in bending of the connector screw Blanks can be re used multiple times Asse...

Страница 11: ...t until its full stop NOTE The instrument will not run while the cover is open If the Cover not in place pop up window is on the screen check the position of the cover and then close this warning wind...

Страница 12: ...gain The run will continue where it left off Note that if the run was paused during the high pressure step the chamber will remain pressurized and therefore locked The Pause feature should not be used...

Страница 13: ...cuation of the facility To stop operation of the system and shut it down Press the STOP button on the software main screen Wait until the system is depressurized and STOP button is greyed out Press Wi...

Страница 14: ...le feature which can be toggled ON or OFF Note Autoscale feature must be turned off for manual scaling of that axis to work Start and Pause Button Pressing the Start button starts the pressure run Dur...

Страница 15: ...en pressurizations the chamber pressure will drop to 0 kpsi i e ambient pressure Temperature set the desired temperature for the pressure run Allow unit at least 30 minutes to reach the desired temper...

Страница 16: ...o a hh mm ss format i e 312 00 05 12 0 Duplicate time values are not allowed in the Ramp mode program The time values entered are additive The software will warn you if you have entered an invalid ram...

Страница 17: ...only on units equipped with electrical heating option Offset Set the pressure level around which the waveform will oscillate Amplitude Set the total amplitude of the pressure waveform For example if...

Страница 18: ...d on the Services tab this feature facilitated communication between the software and the instrument control circuits The use of this feature is reserved for the PBI service personnel Additional Admin...

Страница 19: ...fault password is password See additional information on user management features in Section 3 3 below o Modify Users allows creating or modifying new users and passwords with two levels of privileges...

Страница 20: ...T is equipped with a built in thermocouple and is configured to provide temperature logging within 0 5 C Fine tuning of the temperature reading may require changing the calibration of the thermocouple...

Страница 21: ...vice screen System log runs automatically in a privileged mode none of the users can stop logging or alter the type of information that is being logged o Raw Data Logging and Storage Options If the op...

Страница 22: ...ctivity to an External LIMS System System factory configuration includes an option called LIMS When enabled this option forces user to enter a 12 character alphanumeric run ID before a new run can be...

Страница 23: ...Greater usage may require more frequent maintenance Table 2 Maintenance Schedule for optionally provided air compressor Task Weekly Monthly Annually Check oil levels in all heads and refill if necess...

Страница 24: ...indows Embedded Standard Event Logs for critical errors X Check and correct MS Windows Date Time settings X Run MS Windows Update routine if system is not connected to the network or not configured to...

Страница 25: ...e Section 4 4 Replacing the rubber O ring Step 1 Pull the used rubber O ring orange arrow color of the O ring may vary up and over the metal retaining ring green arrow Step 2 Inspect the area under th...

Страница 26: ...e tubing while the chamber is trying to reach pressure replace closure O ring see instructions above If water continues to flow from this tubing there is an issue with the Closure Check Valve Clean ch...

Страница 27: ...ebiosciences com Click on Contact Us at the top of the page Please provide your name contact information and question s To Order more MicroTubes MicroCaps MicroPestles or other Barocycler accessories...

Страница 28: ...the door by sliding it all the way toward the front of the instrument Note the door error message is not displayed if the door was open at the time software was started Opening the door after softwar...

Страница 29: ...control system If the control software malfunctions or freezes for any reason the confirmation signal will be lost and the heater will be disabled Contact PBI Customer support The unit fails to start...

Страница 30: ...d water discharge through the attached valve would indicate that instrument service is required Contact PBI support if this happens The red tubing is connected to the intensifier seal Leakage of fluid...

Страница 31: ...required at the rear and sides of the Barocycler Electrical Requirements North America Japan configuration 100 120 VAC 50 60 Hz Electric power consumption 100 watts Europe configuration 200 230 VAC 5...

Страница 32: ...The benefit to the customer is a faster time to repair interval and possibly a lower cost repair as well The customer must provide access for the repair of the instrument during normal working hours...

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