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2.3
Safety Messages
DANGER!
Risk of injury to personnel and/or damage to equipment!
Before using the iCELLis 500+ control system, ensure you read and understand the safety instructions
to prevent any damage to the equipment or any physical injury. Pall shall not be held responsible for
any damage that may result from misuse. Misuse includes any use other than that designed for the
iCELLis 500+ bioreactor and control system. Keep this guide handy for later reference. In the event
you have additional questions, please contact Pall.
DANGER!
Risk of injury to personnel and/or damage to equipment!
Use appropriate personal protective equipment (PPE) when moving and using the iCELLis 500+
control system.
DANGER!
Biological hazard!
The biological hazard is a function of the process performed and is under the responsibility of the user.
Appropriate safety risk analysis, depending on the biological material used, should be performed by
the user. Appropriate personal protective equipment must be used.
WARNING!
Risk of injury to personnel and/or damage to equipment!
The iCELLis 500+ control system must be operated by qualified people within a safe environment only.
This equipment is expected to be installed in a controlled environment. Do not use the equipment in
hazardous locations, such as Atmosphere Explosive (ATEX) Environmental operating conditions:
18 - 25 °C, 10 - 70 % relative humidity non-condensing. When not in use, the iCELLis 500+ control
system must be stored in temperatures ranging from 4 ºC - 40 ºC, 80% maximum relative humidity
non-condensing. Keep the iCELLis 500+ control system in a dry place.
ALERT!
Risk of damage to equipment!
This equipment has been designed for indoor use only.
DANGER!
Risk of injury to personnel and/or damage to equipment!
Before installing the iCELLis 500+ control system, ensure that the floor can support the weight of the
system, the ancillary equipment and their content (such as cell culture media).
ALERT!
Risk of damage to equipment!
Never use the equipment in a manner not specified by or clearly prohibited by the manufacturer.
Such inappropriate use may impair the equipment’s built-in protections and would void the warranty.
ALERT!
Risk of damage to equipment!
Do not use the iCELLis 500+ control system in an incubator.
ALERT!
Risk of damage to equipment!
Never position the equipment so that it is difficult to access the machine main power switches, gas inlet
ports and emergency stop buttons. A minimum clearance of 650 mm around the system (front, rear,
left and ride sides) is needed.
WARNING!
Risk of injury to personnel and/or damage to equipment!
Refer to the operating manual of the Temperature Control Unit (TCU) provided within the
documentation of the iCELLis 500+ control system.
Make sure you read and understand all instructions and safety precautions listed in the operating
manual of the TCU before installing or operating your unit.
WARNING!
Risk of injury to personnel and/or damage to equipment!
Place the TCU on an even surface with a base made of nonflammable material.
WARNING!
HOT/COLD surfaces! Risk of injury to personnel and/or damage to equipment!
Always empty the bath of the TCU before moving the unit. Do not drain the bath fluid while it is hot!
Check temperature of bath fluid prior to draining (e.g. by switching the unit on for a short moment).
WARNING!
Bended tubing! Risk of injury to personnel and/or damage to equipment!
Avoid sharp bends in the fluid tubing of the TCU and maintain a sufficient distance from surrounding
walls. Make sure that the tubing is securely attached.
CAUTION!
Risk of injury to personnel and/or damage to equipment!
When the TCU, media pre-heater or the filter heater are active the surfaces and tubes can be hot.
Therefore, exercise particular caution when handling.
ALERT!
Risk of damage to equipment!
Do not disconnect the communication cable between the iCELLis 500+ control system and the TCU
