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In order to maintain the quality of titration results, the burette must be in
good condition and properly calibrated. Generally, the interval at which a
burette needs to be calibrated depends on several factors:
Regulations and standards published by organizations such as the FDA and
ASTM International provide minimum requirements to ensure the quality of
laboratory testing results. Regulations specify that all laboratory
instruments used in sampling & productions including pipette/burette
must be routinely calibrated at suitable intervals.
In the same series, the Clinical and laboratory standards institute (CSLI) has
provided the guidelines for pipette/ burette that specifies these
instruments must be calibrated every 3 to 6 months. And a minimum of two
volumes must be tested with 10 replicas at both nominal and lowest
settings.
Establishing an appropriate calibration frequency minimizes the chances of
incorrect liquid delivery in the laboratory and ensures traceability,
accountability and confidence in the results.
When is burette calibration
required?
Frequency of burette use
Type of liquid dispensed by the burette
Long period of non-usage
Handling and care of burette
Titration applications that require superior accuracy also demand more
frequent calibration
