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2.
The effects of cryotherapy
2.1
Local anaesthesia (analgesia)
The maximal effect is reached immediately (within 10 to 15 seconds) during the
treatment and it will remain effective, depending on circumstances, from 30
minutes to 3 hours after the treatment has been stopped (the average duration
is one hour).
When the skin temperature goes below 15° C, the coldness has the effect of
slowing down the conduction of nervous impulses. However, one should be
aware of the fact that, in vitro, a temperature below 10° C could cause damage to
the nervous system. In vivo, this limit can be fixed between 5 and 7° C. However,
a thermal shock will consist of lowering the skin temperature from 34° C to less
than 15° C, but never reach a temperature lower than 5° C.
Cold will also decrease the irritability of the nociceptors (through depolarisation
of cell membranes).
2.2 Anti-inflammation
The importance of inflammation, of the permeability of the capillaries and of the
cellular response is directly linked to the temperature of the tissue.
A fast application of cold causes a decrease in the production of neurotransmitters,
which are responsible for the inflammation. This makes it possible to decrease
the quantity of the substances that cause pain with 70 to 80 %, which results in a
less intense inflammatory reaction.
By causing a vasoconstriction (arteriolar and capillary), cold will oppose the
vasodilatation of the inflammatory reaction. This vasoconstriction is responsible
for a decrease of the drainage of the blood flow, for a diminution of the hydrostatic
pressure and thus for a reduction of the drainage of liquid. As a result the
plasmaextravasation, responsible for the volume of the oedema, will be limited.
We should draw attention to the fact that cold does not inhibit the drainage of
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